2021
DOI: 10.1186/s41983-021-00291-7
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Assessment of cerebral hemodynamics in multiple sclerosis patients

Abstract: Background Multiple sclerosis (MS) is the most common demyelinating disease of the central nervous system. Autonomic dysfunction is present in a wide range of patients (15–80%) that might present with abnormalities in the regulation of the cardiovascular system, sleep disturbance, urinary symptoms, sexual problems, and temperature regulation problem. Although the predominant view is that of an autoimmune inflammatory condition, changes in brain vasculature can occur and contribute to pathophysi… Show more

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Cited by 2 publications
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“…The inflammatory signaling is thought to be mediated by the CD4 + lymphocytes entering the CNS. 104 The main target of this inflammation is myelinated and non-myelinated protein antigens that cause neuronal destruction. 105 It presents symptoms like gait abnormalities, limb weakness, neuropathies, cognitive deficits, etc.…”
Section: Multiple Sclerosismentioning
confidence: 99%
“…The inflammatory signaling is thought to be mediated by the CD4 + lymphocytes entering the CNS. 104 The main target of this inflammation is myelinated and non-myelinated protein antigens that cause neuronal destruction. 105 It presents symptoms like gait abnormalities, limb weakness, neuropathies, cognitive deficits, etc.…”
Section: Multiple Sclerosismentioning
confidence: 99%