Assessment of Choroidal Topographic Changes by Swept-Source Optical Coherence Tomography After Intravitreal Ranibizumab for Exudative Age-Related Macular Degeneration

Choroidal thickness in non-neovascular versus neovascular age-related macular degeneration: a fellow eye comparative study

“…Ting et al ,40 in a prospective fellow-eye study with a follow-up of 12 months, demonstrated choroidal thinning after monthly intravitreal injections of anti-VEGF in NV AMD. However, CT has been shown to decrease significantly during the first 3 months of anti-VEGF therapy, and then stabilise 41. In our study, CT was measured at a mean of 4.9±3.9 months after the last anti-VEGF injections and this may have limited the confounding effect of anti-VEGF therapy.…”

“…The majority of our patients with NV AMD received intravitreal anti-VEGF treatment, which may cause significant choroidal thinning 40 41. Ting et al ,40 in a prospective fellow-eye study with a follow-up of 12 months, demonstrated choroidal thinning after monthly intravitreal injections of anti-VEGF in NV AMD.…”

Stereotactic radiotherapy in neovascular age-related macular degeneration

“…Interestingly, Shin et al [39] postulated the thinner the choroid the higher the prevalence of intra/subretinal fluid. Opposite to this, Razavi et al [40] associated a thicker choroid to hyperpermeability and enhanced exudation.…”

“…Even though there is still some debate, most studies regarding changes of choroidal thickness following anti-VEGF treatment have demonstrated a decrease in choroidal thickness in nAMD eyes. [41,42] Razavi et al [40] interpreted this effect as a favorable influence of anti-VEGF treatment not only on retinal, but also on the underlying choroidal exudation by reduction of choroidal vascular hyperpermeability.…”

Choroidal Thickness Changes After Intravitreal Ranibizumab for Exudative Age-Related Macular Degeneration

“…Yamazaki et al [9]. and Razavi et al [10]. reported reductions in choroidal thickness after intravitreal injections of ranibizumab.…”