Assessment of Cognitive Impairment in Patients with Cerebral Infarction by MMSE and MoCA Scales

Ou, Chunying; Li, Chuanling; An, Xiaolei; Li, Xiaobin; Guo, Jing

doi:10.29271/jcpsp.2020.03.342

Cited by 7 publications

(4 citation statements)

References 5 publications

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“…The higher the score, the higher the patients' daily living ability. The Mini-cog and MoCA scales [ 10 ] were used to measure the cognitive function of the two groups prior to and following treatment. The total score of Mini-cog ranged from 0 to 30.…”

Section: Methodsmentioning

confidence: 99%

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Efficacy of Fuyuan Xingshen Decoction Combined with Butylphthalide Sodium Chloride Injection in the Treatment of Acute Cerebral Infarction and Its Effect on Hemodynamics

Zhang

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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Objective. This study aims to determine the curative effect of Fuyuan Xingshen Decoction combined with butylphthalide sodium chloride injection in acute cerebral infarction (ACI) treatment and its effect on hemodynamics. Methods. In our hospital, a total of 84 ACI patients from May 2020 to February 2022 were randomly divided into two groups: observation and control (n = 42 each). Fuyuan Xingshen Decoction in combination with butylphthalide sodium chloride injection was provided to the observation group, while the control group received butylphthalide sodium chloride injection alone. Both groups’ clinical efficacy was observed. Before and after treatment, the neurological function of the two groups was evaluated using the National Institutes of Health Stroke Scale (NIHSS), while the daily living ability of both groups was determined using the Barthel index rating scale. Both groups were investigated for their cognitive function, before and after treatment, by using the Mini-Cog scale and Montreal Cognitive Assessment (MoCA) scale. The pulsatility index (PI), peak velocity (Vp), and mean velocity (Vm) of intracranial arteries were measured by transcranial Doppler ultrasonography before and after treatment. The levels of ubiquitin carboxy-terminal hydrolase-1 (UCH-L1), Fibulin-5, and visinin-like protein-1 (VILIP-1) in serum and the expression levels of miR-34c, miR-25, and miR-182 in peripheral blood of the two groups were compared. Both groups were observed for the incidence of adverse reactions. Results. Compared with the control (71.43%), the observation group exhibited a significantly higher effective rate of around 90.48%. In the observation group, the improvement in NIHSS, Barthel index, Mini-cog, and MoCA scores; hemodynamic indexes including Vp, PI, and Vm; serum UCH-L1, Fibulin-5, and VILIP-1 levels; and the miR-34c, miR-25, and miR-182 expression levels in peripheral blood was better than the control group, with significant difference (all P < 0.05 ). The incidence of adverse reactions between the groups demonstrated no significant differences ( P > 0.05 ). Conclusions. Fuyuan Xingshen Decoction combined with butylphthalide sodium chloride injection can effectively improve patients’ daily living ability, neurological function, cognitive function, and cerebral hemodynamics in the treatment of ACI, with good effect and safety.

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Section: Methodsmentioning

confidence: 99%

“…e Barthel index rating scale [9] was used to assess the two groups' daily living ability, with a range of total scores from 0 to 100. e higher the score, the higher the patients' daily living ability. e Mini-cog and MoCA scales [10] were used to measure the cognitive function of the two groups prior to and following treatment.…”

Section: Observational Indicesmentioning

confidence: 99%

Efficacy of Fuyuan Xingshen Decoction Combined with Butylphthalide Sodium Chloride Injection in the Treatment of Acute Cerebral Infarction and Its Effect on Hemodynamics

Zhang

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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“…Impairment of cognitive function not only affects the rehabilitation process of cerebral infraction patients but also affects the social adaptability of patients after rehabilitation. In addition, patients with cerebral infraction can also suffer from abnormal changes in neurological functions such as apraxia, agnosia, sensory disturbance, and visual space disorder, which leads to a significant decline in the patient’s social and working ability [24]. At the same time, accumulating evidence has demonstrated that cognitive impairment will increase the mortality of patients with cerebrovascular diseases [25].…”

Section: Discussionmentioning

confidence: 99%

A Psychological Intervention Program for Patients with Cerebral Infarction

Xu¹,

Tao²,

Dong³

et al. 2023

Dement Geriatr Cogn Disord

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Introduction: Cerebral infarction is one of the most common cerebrovascular diseases. The sequelae caused by cerebral infarction, including limb paralysis, crooked mouth corners, language barriers, etc., seriously affect the patient’s physical and mental health and enthusiasm for rehabilitation training. Therefore, psychological intervention has important positive significance for the rehabilitation and nursing of patients with cerebral infarction. Methods: This is a single-blind controlled study. 168 patients with cerebral infarction who met the inclusion criteria and visited our hospital from January 2018 to January 2020 were randomly divided into a control group (n = 84) and an intervention group (n = 84). The patients in the intervention group received an additional 3-month psychological treatment on the basis of the patients in the control group. The National Institutes of Health Stroke Scale (NIHSS), Activities of Daily Living (ADL) scale, Mini-Mental State Examination (MMSE), and Hamilton Depression Rating Scale (HAMD) were measured before and after the psychological intervention. Results: The 3-month psychological intervention we designed significantly reduced the NIHSS and HAMD scores of patients with cerebral infarction compared with traditional rehabilitation care for cerebral infarction, implying that our psychological intervention courses can improve patients’ cognitive function and suppress patients’ depression. Consistently, our psychological intervention also significantly improved ADL and MMSE scores 3 months after the onset of cerebral infarction patients, implying that this psychological intervention helped patients recover their daily functions relative to conventional care. Conclusion: Psychological intervention can be used as an adjunct therapy in the treatment and nursing of patients with cerebral infarction.

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“…As shown in our study, tDCS and CA were effective only in improving MoCA scores but had no significant effect in improving MMSE, which may be related to the different characteristics between MoCA and MMSE scales. Studies have shown that compared with MMSE, MoCA is more sensitive to recognizing mild cognitive impairment, while MMSE is more suitable for the diagnosis of moderate to severe cognitive impairment ( 36 , 37 ). In other words, MoCA is more likely to identify mild changes in cognitive function.…”

Section: Discussionmentioning

confidence: 99%

Comparative efficacy of 5 non-pharmacological therapies for adults with post-stroke cognitive impairment: A Bayesian network analysis based on 55 randomized controlled trials

Yang

Qiu

et al. 2022

Front. Neurol.

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BackgroundAs a common sequela after stroke, cognitive impairment negatively impacts patients' activities of daily living and overall rehabilitation. Non-pharmacological therapies have recently drawn widespread attention for their potential in improving cognitive function. However, the optimal choice of non-pharmacological therapies for post-stroke cognitive impairment (PSCI) is still unclear. Hence, in this study, we compared and ranked 5 non-pharmacological therapies for PSCI with a Bayesian Network Meta-analysis (NMA), to offer a foundation for clinical treatment decision-making.MethodsPubMed, EMBASE, Web of Science, Cochrane Central Register of Controlled Trials, Chinese Biomedical Medicine, China National Knowledge Infrastructure, Wangfang Database, and China Science and Technology Journal Database were searched from database inception to December 31, 2021, to collect Randomized Controlled Trials for PSCI. All of the studies were assessed (according to Cochrane Handbook for Systematic Reviews) and then data were extracted by two researchers separately. Pairwise meta-analysis for direct comparisons was performed using Revman. NMA of Bayesian hierarchical model was performed by WinBUGS and ADDIS. STATA was used to construct network evidence plots and funnel plots.ResultsA total of 55 trials (53 Two-arm trials and 2 Three-arm trials) with 3,092 individuals were included in this study. In the pair-wise meta-analysis, Transcranial Magnetic Stimulation (TMS), Virtual Reality Exposure Therapy (VR), Computer-assisted cognitive rehabilitation (CA), Transcranial Direct Current Stimulation (tDCS), and Acupuncture were superior to normal cognition training in terms of MoCA, MMSE, and BI outcomes. Bayesian NMA showed that the MoCA outcome ranked Acupuncture (84.7%) as the best therapy and TMS (79.7%) as the second. The MMSE outcome ranked TMS (76.1%) as the best therapy and Acupuncture as the second (72.1%). For BI outcome, TMS (89.1%) ranked the best.ConclusionsTMS and Acupuncture had a better effect on improving cognitive function in post-stroke patients according to our Bayesian NMA. However, this conclusion still needs to be confirmed with large sample size and high-quality randomized controlled trials.Registrationhttps://inplasy.com (No. INPLASY202260036).

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Assessment of Cognitive Impairment in Patients with Cerebral Infarction by MMSE and MoCA Scales

Cited by 7 publications

References 5 publications

Efficacy of Fuyuan Xingshen Decoction Combined with Butylphthalide Sodium Chloride Injection in the Treatment of Acute Cerebral Infarction and Its Effect on Hemodynamics

Efficacy of Fuyuan Xingshen Decoction Combined with Butylphthalide Sodium Chloride Injection in the Treatment of Acute Cerebral Infarction and Its Effect on Hemodynamics

A Psychological Intervention Program for Patients with Cerebral Infarction

Comparative efficacy of 5 non-pharmacological therapies for adults with post-stroke cognitive impairment: A Bayesian network analysis based on 55 randomized controlled trials

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