Assessment of colorectal length using the electromagnetic capsule tracking system: a comparative validation study in healthy subjects

Abstract

The 3D-Transit system allows accurate and reliable determination of colorectal length compared with MRI-derived colorectal length and between days. Antegrade or retrograde capsule movement relative to this centreline, as well as the length and speed of movements, may be determined by future studies to allow better classification and treatment in patients with dysmotility.

Normative values for region‐specific colonic and gastrointestinal transit times in 111 healthy volunteers using the 3D‐Transit electromagnet tracking system: Influence of age, gender, and body mass index

“…13 The two methods were found to be comparable, though the 3D-Transit system's WGTT estimates were seen to be longer, a finding attributed to the size of the capsule in relation to ROMs. 19 To date, the ambulatory 3D-Transit system has not been directly compared against similar, capsule-based systems such as the WMC. 19 To date, the ambulatory 3D-Transit system has not been directly compared against similar, capsule-based systems such as the WMC.…”

“…MathWorks Inc, Massachusetts, USA) for the extraction of regionspecific colonic transit times using the method described by Mark et al 19 Briefly, this involved first cleaning the recordings (performed by two investigators-GKN and EBM) to identify movements of the capsule that reflect real GI activity and filter out artifacts such as those caused by detector movement that distort a capsule's 3D-trajectory ( Figure 1A). The following six distinct anatomical landmarks of the colon were then identified from the "cleaned" recordings by Where retrograde motion of a capsule occurred between segments of the colon, that is movement of the capsule back into the preceding segment, the landmark was identified as the point in time when the capsule last moved into the distal segment without further retrograde motion.…”

“…6,11 Such information can be obtained using the Motilis 3D-Transit system (Motilis Medica, SA, Lausanne, Switzerland), an emerging research tool that tracks the location and orientation of up to three ingestible electromagnetic capsules. [13][14][15][16] However, the novelty of the system lies in providing a detailed analysis of colonic motility in terms of regionspecific colonic transit times, 17,18 anatomical lengths of colonic segments, 19 and colonic motility patterns. [13][14][15][16] However, the novelty of the system lies in providing a detailed analysis of colonic motility in terms of regionspecific colonic transit times, 17,18 anatomical lengths of colonic segments, 19 and colonic motility patterns.…”

Ambulatory assessment of colonic motility using the electromagnetic capsule tracking system

“…Periods with data loss and missing data were categorized as “missing data periods.” Movements slower than 4 cm/h or shorter than 4 cm were excluded from subsequent analysis and categorized as “non‐movement periods” and reported as the fraction of transit time without detected movement, where “missing data periods” are not included. The anatomical shape and the length of the colorectum were estimated with a previously described method allowing for a 3D representation of the capsule’s trajectory through the colon (Figure B). Velocity of capsule progression relative to the trajectory was calculated as displacement per minute between data points inside the classified movements.…”

“…Velocity of capsule progression relative to the trajectory was calculated as displacement per minute between data points inside the classified movements. The trajectory was divided into four segments: (a) cecum and ascending colon, (b) transverse colon, (c) descending colon, and (d) sigmoid colon and rectum . The recordings were observed in a space‐time representation of capsule activity through the colon (Figure C).…”