Assessment of Common Cyanotoxins in Cyanobacteria of Biological Loess Crusts

Dulić, Tamara; Svirčev, Zorica; Malešević, Tamara Palanački; Faassen, Elisabeth J.; Savela, Henna; Hao, Qingzhen; Meriluoto, Jussi

doi:10.3390/toxins14030215

Cited by 9 publications

(3 citation statements)

References 95 publications

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“…AEG and DAB isomers were detected in 30% and 43% of the samples, respectively, while BAMA was found in less than 8% of the samples and BMAA was not observed in any sample [37]. No BMAA was found in any of the analyzed biological loess crusts (BLCs, terrestrial samples) taken from various locations in Serbia, China and Iran [52]. These results indicate that while BMAA occurs in many ecosystems, it is not present in every ecosystem.…”

Section: Occurrence Of Bmaa In Cyanobacteria and Microalgaementioning

confidence: 79%

Environmental Neurotoxin β-N-Methylamino-L-alanine (BMAA) as a Widely Occurring Putative Pathogenic Factor in Neurodegenerative Diseases

et al. 2022

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In the present review we have discussed the occurrence of β-N-methylamino-L-alanine (BMAA) and its natural isomers, and the organisms and sample types in which the toxin(s) have been detected. Further, the review discusses general pathogenic mechanisms of neurodegenerative diseases, and how modes of action of BMAA fit in those mechanisms. The biogeography of BMAA occurrence presented here contributes to the planning of epidemiological research based on the geographical distribution of BMAA and human exposure. Analysis of BMAA mechanisms in relation to pathogenic processes of neurodegeneration is used to critically assess the potential significance of the amino acid as well as to identify gaps in our understanding. Taken together, these two approaches provide the basis for the discussion on the potential role of BMAA as a secondary factor in neurodegenerative diseases, the rationale for further research and possible directions the research can take, which are outlined in the conclusions.

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Section: Occurrence Of Bmaa In Cyanobacteria and Microalgaementioning

confidence: 79%

Environmental Neurotoxin β-N-Methylamino-L-alanine (BMAA) as a Widely Occurring Putative Pathogenic Factor in Neurodegenerative Diseases

et al. 2022

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“…The monitoring of water quality will consequently gain more relevance, even in small catchments. While one study that investigated soil crusts, did not detect cyanotoxin-producing genes [61] , their presence on the rock surface cannot be excluded in general. Unfortunately, most of the studies on secondary metabolites producing cyanobacteria have been conducted in aquatic environments and no strains have been isolated from non-aquatic or semi-aquatic environments with this focus.…”

Section: Discussionmentioning

confidence: 99%

Lithic bacterial communities: ecological aspects focusing onTintenstrich communities

Pittino,

Fink,

Oliveira

et al. 2024

Preprint

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Tintenstrich communities (TC) are mainly composed by Cyanobacteria developing on rock substrates and forming physical structures strictly connected to the rock itself. Endolithic and epilithic bacterial communities are important because they contribute to nutrients release within run-off waters flowing on the rock surface. Despite them being ubiquitous, little information about their ecology and main characteristics is available. In this paper, we characterized the bacterial communities of rock surfaces of TC in Switzerland through Illumina sequencing and investigated their bacterial community composition on two substrate types (silicious and limestone rocks) through multivariate models. Our results show that Cyanobacteria and Proteobacteria are the predominant phyla in this environment. Bacterial alpha diversity was higher on limestone than on siliceous rock, and beta diversity of siliceous rock varied with changes in rock surface structure. Here we provide novel insights into the bacterial community composition of TC, their differences from other lithic communities, and the effects of the rock substrate and structure.

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“…The detection of the mcy E gene in all the samples from Joanes I Reservoir indicates that the cyanobacterial species present in this water body have the ability to synthesize microcystin. However, to confirm its expression, it is necessary to carry out biochemical analyses (LC/MS and Elisa, among others) to verify whether the toxic strains are in active production [ 18 , 46 ]. In the present work, microcystin analysis was not performed by LC/MS because the methodology was not implemented in the available equipment.…”

Section: Discussionmentioning

confidence: 99%

Identification of Cyanobacteria and Its Potential Toxins in the Joanes I Reservoir, Bahia, Brazil

Menescal

Almeida

Sales

et al. 2023

Toxins

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The Joanes I Reservoir is responsible for 40% of the drinking water supply of the Metropolitan Region of Salvador, Bahia, Brazil. For water sources such as this, there is concern regarding the proliferation of potentially toxin-producing cyanobacteria, which can cause environmental and public health impacts. To evaluate the presence of cyanobacteria and their cyanotoxins in the water of this reservoir, the cyanobacteria were identified by microscopy; the presence of the genes of the cyanotoxin-producing cyanobacteria was detected by molecular methods (polymerase chain reaction (PCR)/sequencing); and the presence of toxins was determined by liquid chromatography with tandem mass spectrometry (LC-MS/MS). The water samples were collected at four sampling points in the Joanes I Reservoir in a monitoring campaign conducted during the occurrence of phytoplankton blooms, and the water quality parameters were also analysed. Ten cyanobacteria species/genera were identified at the monitoring sites, including five potentially cyanotoxin-producing species, such as Cylindrospermopsis raciborskii, Cylindrospermopsis cf. acuminato-crispa, Aphanocapsa sp., Phormidium sp., and Pseudanabaena sp. A positive result for the presence of the cylindrospermopsin toxin was confirmed at two sampling points by LC-MS/MS, which indicated that the populations are actively producing toxins. The analysis of the PCR products using the HEPF/HEPR primer pair for the detection of the microcystin biosynthesis gene mcyE was positive for the analysed samples. The results of this study point to the worrisome condition of this reservoir, from which water is collected for public supply, and indicate the importance of the joint use of different methods for the analysis of cyanobacteria and their toxins in reservoir monitoring.

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Assessment of Common Cyanotoxins in Cyanobacteria of Biological Loess Crusts

Cited by 9 publications

References 95 publications

Environmental Neurotoxin β-N-Methylamino-L-alanine (BMAA) as a Widely Occurring Putative Pathogenic Factor in Neurodegenerative Diseases

Environmental Neurotoxin β-N-Methylamino-L-alanine (BMAA) as a Widely Occurring Putative Pathogenic Factor in Neurodegenerative Diseases

Lithic bacterial communities: ecological aspects focusing onTintenstrich communities

Identification of Cyanobacteria and Its Potential Toxins in the Joanes I Reservoir, Bahia, Brazil

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