Assessment of components of Gingko biloba leaves collected from different regions of China that contribute to its antioxidant effects for improved quality monitoring

Li, Li; Zhang, Mingxu; Wang, Xiaoyue; Yang, Yun-Li; Gong, Xue; Wang, Congcong; Xu, Jinfan; Li, Min-Hui

doi:10.1590/fst.33620

Cited by 5 publications

(2 citation statements)

References 13 publications

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“…Kaur et al (2012) extracted G. biloba leaf with 60% ethanol with five different extraction methods as maceration, Soxhlet, ultrasound assisted, the use of an orbital shaker, and microwave and tested antioxidant activities of all extracts utilizing of DPPH • scavenging (48.2-93.4 mg trolox/g), ABTS •+ scavenging (54.7-99.8 mg trolox/g), and FRAP (18.1-41.7 mg trolox/g) assays. Li et al (2021) determined that the IC50 values of the ethanol extracts of G. biloba leaves from fourteen different regions varied between 0.131-0.461 mg/mL in ABTS •+ scavenging assay.…”

Section: Discussionmentioning

confidence: 99%

A study on phytochemical composition, antioxidant, and anti-cancer activities of Gingko biloba L.

YILMAZ,

DEVECİ,

TEL-ÇAYAN

2023

Comm. J. Biol.

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The study aims to investigate the phytochemical composition, antioxidant potential, and anti-cancer activities of Ginkgo biloba L. leaf methanol extract. In this study, the phytochemical compounds, total phenolic and flavonoid contents of G. biloba leaf methanol extract were investigated. Additionally, antioxidant and anti-cancer activities [against HT-29 (human colon cancer line), HeLa (human cervical cancer line), and HEK-293 (human embryonic kidney cell line)] were assayed. The main phytochemical compounds were identified as gallic (0.94±0.01 mg/g), p-hydroxy benzoic (0.71±0.01 mg/g), and protocatechuic (0.60±0.02 mg/g) acids in G. biloba leaf methanol extract by HPLC. The total phenolic and total flavonoid contents were measured as 71.20±0.42 µg GAE/mg extract and 13.24±0.35 µg QE/mg extract, respectively. The high antioxidant activity was found in ABTS•+ assay (89.04±0.71%) while moderate antioxidant activity was observed in DPPH• (43.31±0.75%), metal chelating (49.04±0.49%), CUPRAC (absorbance: 0.85±0.01), and phosphomolybdenum (absorbance: 1.16±0.02) assays at 400 µg/mL. The IC50 values of G. biloba leaf methanol extract on HT-29, HeLa, and HEK-293 cell lines were recorded as 406.70±1.55, 84.86±0.98, and >800 µg/mL, respectively. The present study features a new addition to the antioxidant and anti-cancer properties of the therapeutically valuable G. biloba with its phytochemical content.

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Section: Discussionmentioning

confidence: 99%

A study on phytochemical composition, antioxidant, and anti-cancer activities of Gingko biloba L.

YILMAZ,

DEVECİ,

TEL-ÇAYAN

2023

Comm. J. Biol.

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“…When examining ethanol extracts from G. biloba leaves, large differences in scavenger properties are found depending on the origin of plants from 14 regions of China. Some authors were looking for a correlation between the resulting IC50 values when examining the antioxidant properties of G. biloba extracts and their constituent substances using the ABTS (2,2 azino-bis (3ethylbenzothiazoline-6-sulfonic acid)) method [37]. They found a high negative correlation between IC50 and the concentration of two flavonoids in the extracts -isoginkgetin and ginkgetin (r = -0.761, P < .01 and -0.703, P <.01, respectively).…”

Section: Antioxidant Properties Of Ginkgo Biloba Extractsmentioning

confidence: 99%