Assessment of composition and biological activity of Arctium lappa leaves extracts obtained with pressurized liquid and supercritical CO2 extraction

Souza, Ariádine Reder Custódio de; Stefanov, S.; Bombardelli, Michele Cristiane Mesomo; Corazza, Marcos L.; Stateva, Roumiana P.

doi:10.1016/j.supflu.2019.104573

Cited by 29 publications

(14 citation statements)

References 52 publications

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“…Additionally, the TPC was higher (36.02 mg GAE/g) for moringa leaf extracts obtained by Soxhlet using water (Sreelatha & Padma, 2009) et al, 2013). Corazza, & Stateva, 2019) and oregano leaf extracts (2.9 to 6.9 μmol Trolox/g) (García-Pérez et al, 2019). A previous study with moringa leaf extracts showed extractions with medium to high polarity solvents had more antioxidant potential by the FRAP method (Oldoni et al, 2019).…”

Section: Antioxidant Activity Of Extractsmentioning

confidence: 97%

Extraction of compounds from Moringa oleifera leaves using supercritical CO₂ plus ethanol as a cosolvent

Silva

Trancoso

Tormen

et al. 2022

J Food Process Engineering

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Extracts of compounds fromMoringa oleifera leaves were obtained by supercritical extraction with CO 2 using ethanol as a cosolvent (scCO 2 + EtOH). The experimental conditions were investigated by varying temperature (35-80 C), pressure (15-25 MPa), and mass ratio between ethanol and raw material. The phenolic acids (gallic, vanillic, and p-coumaric acids) and flavonoids (catechin) were identified in all extracts, except for the extract obtained without the cosolvent. The main compounds by GC-MS were 1-triacontanol, nonacosane, heptacosane, phytol, γ-tocopherol, and α-tocopherol. Extracts obtained at 35 C showed the highest values of total phenolic compounds, DPPH, and FRAP, however, the lowest extraction yield. The central point extraction conditions (60 C and 20 MPa) had the best-combined results for yield (4.4%), total phenolic compounds (24 ± 1 mg GAE/g), DPPH (77 ± 2 μmol Trolox/g), FRAP (265 ± 9 μmol Trolox/g) and the presence of bioactive compounds. Practical ApplicationsSupercritical fluid extraction with CO 2 is a clean technology that employs low temperatures, producing high-quality extracts. Moringa oleifera leaf extracts showed different compositions according to the experimental conditions evaluated. The use of ethanol as a cosolvent and high temperatures positively influenced the extraction yield. All extracts showed antioxidant potential. Catechin, gallic, vanillic, and pcoumaric acids were the main phenolic compounds. The extract obtained at the central point condition had better antioxidant potential, yield, and bioactive compounds.

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Section: Antioxidant Activity Of Extractsmentioning

confidence: 97%

Extraction of compounds from Moringa oleifera leaves using supercritical CO₂ plus ethanol as a cosolvent

Silva

Trancoso

Tormen

et al. 2022

J Food Process Engineering

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“…Pressurized liquid extractions of BSG were performed in a semi-continuous system, which was presented in previous works [14,33]. Briefly, the experimental setup is composed of a jacketed extraction vessel of 20.44 cm 3 internal volume (17.2 cm height and 1.24 cm in diameter) with an electrical-heating and thermocouples and temperature controller.…”

Section: Pressurized Liquid Extraction (Ple)mentioning

confidence: 99%

Pressurized liquid extraction of brewer’s spent grain: Kinetics and crude extracts characterization

Herbst

Hamerski

Errico

et al. 2021

Journal of Industrial and Engineering Chemistry

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In this study, extraction yield of valuable compounds from brewer's spent grain (BSG) using pressurized liquid extraction (PLE) was investigated varying temperature, solvent type, and flow rate at a constant pressure. The results were compared with Soxhlet extractions using the total phenolic compounds (TPC), total flavonoid compounds (TFC), antioxidant activity (AA), reducing sugars (RS), and total reducing sugars (TRS) as indices. The highest PLE extraction yield was 20.1 wt%, at 120°C, 2 mL/min using ethanol to water volume ratio of 0.5, at 10 MPa. The TPC, TFC, and AA content were favored by water and water/ethanol extractions and temperature increase. The highest AA was obtained with water at 120 °C and 4 mL/min achieving 9944, 4769 and 4096 µmol TE/100 g of BSG extract, respectively. PLE was capable of present high extraction yields maintaining the RS and TRS in the BSG matrix. In addition, BSG was defatted with compressed propane before the extraction with PLE, showing that 2 compressed propane is highly efficient in recovering the lipid fraction from BSG. The results demonstrated a great potential of water and different EtOH/Water solvent ratio at pressurized conditions for obtaining bio-compounds of BSG in a crude extract with expressive biological activity.

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“…[9,23,35,37] The polysaccharides used as an inulin source are present mainly in the A. lappa roots. [32] Among the main active secondary metabolites that have been isolated from burdock are: (i) phenolic compounds such as: phenolic acids (caffeic, chlorogenic, cynarin acids); lignans (arctiin, arctigenin and lapalols), flavonoids (quercetin, quercitrin, rutin and luteolin), and tannins; [8,16,30,38,46] (ii) terpenoids compounds such as terpenes (lupeol, amyrin, phytol, βeudesmol) and phytosterols (sitosterol and stigmasterol); [27,30,47] and (iii) nitrogen or sulfur-containing compounds (polyacetylenes: arctinone, arctinol, arctinal, and others) (Figure 3). [39,48] In simple or polymer forms, phenolic compounds are chemically defined as chemical structures with high antioxidant power due to hydroxyls and aromatic rings.…”

Section: Phytochemical Composition Of a Lappamentioning

confidence: 99%

Phytochemicals and Biological Activities of Burdock (Arctium lappa L.) Extracts: A Review

Souza¹,

Oliveira

Fontana

et al. 2022

Chemistry & Biodiversity

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Arctium lappa L., also known as burdock, is an edible wild plant which has the ability to grow in distinct environments and is considered a weed in several parts of the world. This species has great value in the biological and medical fields with its major secondary components being phenolic compounds and terpenes, substances rich in desired biological activities as antioxidant, antimicrobial, antitumor and anti‐inflammatory. In addition, burdock leaves extracts have shown a modulatory effect on the complement system, which plays an important role in the development of inflammatory diseases, with an inhibitory effect on all complement pathways. Thus, natural products with those relevant activities are promising agents for healthcare applications. Therefore, the species A. lappa may represent an interesting asset for researching and developing new therapies for inflammatory afflictions.

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Assessment of composition and biological activity of Arctium lappa leaves extracts obtained with pressurized liquid and supercritical CO2 extraction

Cited by 29 publications

References 52 publications

Extraction of compounds from Moringa oleifera leaves using supercritical CO₂ plus ethanol as a cosolvent

Extraction of compounds from Moringa oleifera leaves using supercritical CO₂ plus ethanol as a cosolvent

Pressurized liquid extraction of brewer’s spent grain: Kinetics and crude extracts characterization

Phytochemicals and Biological Activities of Burdock (Arctium lappa L.) Extracts: A Review

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Assessment of composition and biological activity of Arctium lappa leaves extracts obtained with pressurized liquid and supercritical CO2 extraction

Cited by 29 publications

References 52 publications

Extraction of compounds from Moringa oleifera leaves using supercritical CO2 plus ethanol as a cosolvent

Extraction of compounds from Moringa oleifera leaves using supercritical CO2 plus ethanol as a cosolvent

Pressurized liquid extraction of brewer’s spent grain: Kinetics and crude extracts characterization

Phytochemicals and Biological Activities of Burdock (Arctium lappa L.) Extracts: A Review

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Extraction of compounds from Moringa oleifera leaves using supercritical CO₂ plus ethanol as a cosolvent

Extraction of compounds from Moringa oleifera leaves using supercritical CO₂ plus ethanol as a cosolvent