This invitro study aims to assess the potency of new temporatory restorative material Orafil LC with other temporary restoratives: Zinc oxide eugenol and Cavit G in preventing microleakage during the inter-appointment period of endodontic treatment.Endodontic access cavity was prepared on 60 premolar teeth and restored with 3 different temporary restorative materials in the respective groups. (n=20)The teeth were stored in methylene blue stain and were sectioned to be observed under a compound microscope at 1,2,3 and 7 days to access coronal microleakage and further investigations were under a scanning electron microscope. All the tested materials showed microleakage with maximum leakage in Zinc oxide eugenol followed by Cavit G and Orafil LC. Orafil LC showed the least microleakage.Orafil LC showed least microleakage when compared with other temporary restorative materials used in this study