Assessment of Drug Use Pattern Using WHO Prescribing Indicators

Shrestha, Binaya; Dixit, Siddharth

doi:10.3126/jnhrc.v16i3.21424

Cited by 15 publications

(11 citation statements)

References 14 publications

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“…The majority (94.59) of the drugs were prescribed by generic name, and the rest were prescribed by their brand names which was not in line with WHO guidelines recommendation of 100% generic prescription. The proportion of generic prescription was lower compared with findings by [31] results of a study in Saudi Arabia (38.06%) [5].…”

Section: Discussioncontrasting

confidence: 69%

Appropriateness and Pattern of Antibiotic Prescription in Pediatric Patients at Adigart General Hospital, Tigray, Ethiopia

Yehualaw

Taferre

Bantie

et al. 2021

BioMed Research International

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Background. Inappropriate and unnecessary use of antibiotics can increase morbidity, mortality, medical expenses or patient cost, and microbial antibiotic resistance. However, in developing countries like Ethiopia, information regarding appropriateness of antibiotic prescribing pattern to guide improvement strategies is scant. Objective. The aim of this study was to assess appropriateness and pattern of antibiotic prescription in pediatric patients at pediatric ward of Adigrat General Hospital. Methods. Hospital-based retrospective cross-sectional study was conducted to assess the antibiotic prescribing pattern in pediatric inpatient and outpatient ward of Adigrat General Hospital from December 1, 2018 to April 30, 2019. Data was collected by using structured data collection checklist, and the systematic random sampling technique was employed to enroll the required sample size during the study period. Appropriateness of drug use in pediatrics was evaluated using Ethiopian Standard Treatment guideline and WHO pediatric guideline. Result. A total of 692 pediatric patients’ medical charts were reviewed. The median age of patients on antibiotics was 3.26 years (IQR: 2-4). Majority (49.13%) of the patients were hospitalized for 5-9 days. SCAP (195), tonsillitis (114), and cellulitis (99) were most frequently encountered pediatric diseases. Penicillins (37.86%) followed by cephalosporins (31.79%) antibiotics were the most prescribed antibiotics in pediatric wards. This study also showed that ceftriaxone and ceftriaxone+amoxicillin were the most frequently used single and combination antibiotics, respectively. The prescribing practices were not stick to WHO core indicators and standards. Inappropriate prescription of antibiotics was observed in 28.3% of patients. Advanced age of children, children aged between 6 to 10 years ( AOR = 3.225 ; CI = 1.080 − 9.630 ; P = .036 ) and 11-18 years ( AOR = 18.691 ; CI = 5.156 − 67.756 ; P = .000 ), was the independent determinant of inappropriate drug use. Conclusion. Inappropriate antibiotic prescribing was encountered in 28.3% of children. The rate of generic prescription was not in line with WHO recommendation. Advanced age of children was the independent factor for inappropriate use of antibiotics.

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Section: Discussioncontrasting

confidence: 69%

Appropriateness and Pattern of Antibiotic Prescription in Pediatric Patients at Adigart General Hospital, Tigray, Ethiopia

Yehualaw

Taferre

Bantie

et al. 2021

BioMed Research International

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“…Minimizing the use of injections not only reduces the cost of therapy but also lower the risk of complications related to parenteral use (19). In contrast to the results of other studies from Nepal (71%), Yemen (46%) and West Ethiopia (28.3%), we found low percentages of injection use in the present study (5.1%), (16,27,28).…”

Section: In This Retrospective Analysis Of Patient Data From the Obesity Outpatient Clinic Of Istanbul Medeniyet University Goztepe Traincontrasting

confidence: 91%

“…Similarly, studies from Northwestern Ethiopia and India reported values within the acceptable range of 1.72 and 1.8, respectively (14,15). Several studies from different countries reported average number of drugs per encounter values higher than our results and WHO standards ranging from 2.2 to 5.85 (4,5,(16)(17)(18)(19)(20).…”

Section: In This Retrospective Analysis Of Patient Data From the Obesity Outpatient Clinic Of Istanbul Medeniyet University Goztepe Trainsupporting

confidence: 71%

“…Overuse of antibiotics, which is an indicator of irrational drug use, is of importance in terms of increasing the risk for emergence of the antibiotic resistance (5,16,17). In our study, the percentage of encounters with an antibiotic prescribed was 2.8% which was normal as compared to the standard value (≤30%).…”

Section: In This Retrospective Analysis Of Patient Data From the Obesity Outpatient Clinic Of Istanbul Medeniyet University Goztepe Trainmentioning

confidence: 50%

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Üçüncü basamak bir hastanenin obezite polikliniğinde Dünya Sağlık Örgütü temel reçete göstergeleri kullanılarak akılcı ilaç kullanımının değerlendirilmesi

Özdamar

Mutlu

2021

Ege Tıp Dergisi

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The aim of this study was to evaluate the rational use of drugs prescribed in the obesity outpatient clinic of a tertiary care hospital by using WHO prescribing indicators. Materials and Methods:The patients that admitted to obesity outpatient clinic between April 1, 2016-August 1, 2017 were reviewed retrospectively. Parameters such as patients' demographic characteristics (age, sex), body mass index, comorbid diseases, number of prescribed drugs, drug names, dosage forms and routes of drug administration were evaluated. Prescriptions were analyzed according to the WHO core prescribing indicators such as average number of drugs per encounter, percentage of drugs prescribed by generic name, percentage of encounters with an antibiotic prescribed, percentage of encounters with an injection prescribed and percentage of drugs prescribed from essential drugs. Results: The mean age of the patients was 47.5±12.4 years and most of them were female (88.1%). Essential hypertension was the most common co-morbid disease (33%). Vitamin D3 (cholecalciferol), (23.7%) was the most frequently prescribed drug. The average number of drugs per encounter was 1.7. The percentage of drugs prescribed by generic name was 0%. Antibiotics were prescribed in 14 (2.8%) patients and injections were prescribed in 26 (5.2%) patients. The percentage of drugs from essential drug list was 61.4%. Conclusion:We demonstrated that the prescribing indicators such as the average number of drugs per encounter and the percentage of encounters with an antibiotic and injection prescribed were appropriate as compared to WHO standard values, parameters such as the percentage of drugs prescribed by generic name and the percentage of drugs prescribed from essential drug list was quite far from the WHO ideal values. The findings of this study will provide contributions to implement appropriate interventions by health authorities to promote rational drug use.

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“…A study conducted in Nepal Katamandu medical college teaching hospital showed poly pharmacy (Average no. of prescription per encounter was 5.8 )and commonly used brand names for prescribing of the drugs 6 This study assessed the drug prescribing pattern in outpatient pharmacy of Jigjiga University, Sheikh Sultan Hassan Yabere Referral Hospital by using WHO prescribing indicator use.…”

Section: Introductionmentioning

confidence: 99%

Drug use pattern using WHO prescribing indicators at Sheikh Sultan Hassan Yabere Referral Hospital, Eastern Ethiopia: A cross sectional study

Warsame

2020

J. Drug Delivery Ther.

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Introduction: In order to enhance rational drug use, it is very important to assess the prescribing pattern of the facilities using standard prescribing checklists. Hence, the aim of this study was to assess drug use pattern using WHO prescribing indicators at Sheikh Hassan Sultan Yabere Referral Hospital, Eastern Ethiopia. Objective: the objective of this study is to assess drug use pattern using WHO prescribing indicators at Sheikh Hassan Sultan Yabere Referral Hospital, Eastern Ethiopia 2019 Method: Retrospective study design was employed to assess the current drug prescribing pattern of Sheikh Hassan Sultan Yabere Referral Hospital.Six Month prescription papers from December 1, 2018 to May 31, 2019 were surveyed. A total of 600 prescriptions that were selected using systematic random sampling were reviewed. Data was collected from prescriptions at outpatient pharmacy. The data was entered to excel and analyzed and presented with tables and charts. Results: The average number of drugs prescribed per encounter or mean was 1.98 with a range between one and six drugs. The percentage of encounters in which an antibiotic or injection prescribed were 60 % (n=600) and 2.5 % (n=600) respectively. The percentage of drugs prescribed by generic name and from an essential drug list were 89.5 % (n=600) and 98.99% (n=600). The commonly prescribed forms of antibiotics were Amoxicillin (19.15%), Amoxicillin/Clavulunate (17.41) and Azithromycin (16.83%).The most commonly prescribed injection was Ceftriaxone (52.14%). Conclusion: This study revealed major deviation from standard WHO recommended rational prescribing practice with regard to antibiotic use. The study also showed deviation from WHO standard with regard to use of generic name and prescribing from national formulary/Essential drug list. Keywords: Rational drug use, prescribing pattern, WHO prescribing indicators Jigjiga, Somali Region.

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Assessment of Drug Use Pattern Using WHO Prescribing Indicators

Cited by 15 publications

References 14 publications

Appropriateness and Pattern of Antibiotic Prescription in Pediatric Patients at Adigart General Hospital, Tigray, Ethiopia

Appropriateness and Pattern of Antibiotic Prescription in Pediatric Patients at Adigart General Hospital, Tigray, Ethiopia

Üçüncü basamak bir hastanenin obezite polikliniğinde Dünya Sağlık Örgütü temel reçete göstergeleri kullanılarak akılcı ilaç kullanımının değerlendirilmesi

Drug use pattern using WHO prescribing indicators at Sheikh Sultan Hassan Yabere Referral Hospital, Eastern Ethiopia: A cross sectional study

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