Assessment of drugs in schizophrenia.

Assessment of Anti-Psychotic Drugs

“…Controlling out all possible variables in a complex but realistic environmental setting may not always be desirable. As Leff (1976) has forcefully pointed out, controlling for all social influences in the study design might deprive the investigator of very useful information about interactions between noncontrolled environmental factors and test drug. Careful recording of environmental variables may thus be preferable to trying to allocate them equally between drug and placebo groups (Leff, 1976).…”