Assessment of endocrine disruptor effects of levonorgestrel and its photoproducts: Environmental implications of released fractions after their photocatalytic removal

Valderrama, Jhon Fredy Narváez; Grant, Hannah; Gil, Vanessa Correa; Porras, Jazmín; Sanchez, Julio C.; Duque, Luz Fanny Ocampo; Sossa, Ramiro Ríos; Castillo, Juan Carlos Quintana

doi:10.1016/j.jhazmat.2019.02.095

Cited by 22 publications

(9 citation statements)

References 32 publications

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“…The icing changes from the morning of January 6. With the increase of rainfall in the next five days, the icing thickness of the line will also increase, but the icing changes are different according to the changes of wind speed and temperature [21]. Based on the measured data in Table 3, compare the predicted ice thickness of the line between the original system and the system in this paper, as shown in Table 3.…”

Section: Experimental Analysismentioning

confidence: 99%

Research on Dynamic Assessment System of Composite Fault Risk of Transmission Line Based on Blockchain Energy

Liu

Jia

Ding

et al. 2022

Wireless Communications and Mobile Computing

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In order to study the dynamic assessment system of composite fault risk of transmission line based on blockchain energy and in order to study the transmission line compound fault risk dynamic assessment system based on blockchain, firstly, according to the coupling relationship between power grid and natural disasters, the information resources such as data collected by power grid intelligent devices and natural meteorology are excavated, and the overall architecture of power grid disaster early warning and decision-making system supported by blockchain is built. Then, from the perspective of risk, combined with analytic hierarchy process, an index system for reasonable evaluation of distribution network fault benchmark risk is established. Quantitative assessment and risk classification shall be carried out for the failure probability, failure impact consequence, and comprehensive failure risk, so as to facilitate the adoption of risk response measures. Finally, taking several 220 kV lines in the northwest and central part of a city as examples, the icing prediction analysis verifies the feasibility and effectiveness of the proposed power grid disaster early warning decision system based on blockchain to predict the icing thickness. The experimental results show that taking the icing disaster as an example, the MPC method is used to modify the icing thickness prediction model, improve the accuracy of the icing prediction model, and verify the feasibility and effectiveness of the prediction and early warning system based on blockchain.

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Section: Experimental Analysismentioning

confidence: 99%

Research on Dynamic Assessment System of Composite Fault Risk of Transmission Line Based on Blockchain Energy

Liu

Jia

Ding

et al. 2022

Wireless Communications and Mobile Computing

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“…Such compounds include levonorgestrel (contraceptive) was found in WWTP effluent and in aquatic environments. It was found that low concentrations of levonorgestrel and its fractions caused a reduction in pregnancy maintenance in some aquatic species and humans (32). Also, it was found that alkylphenol (nonylphenol and oxylphenol) and perfluoroalkyl substance exposure in women is associated with endometrial (the most common gynecological cancer in the United States) and breast cancer development (33,34).…”

Section: Environmental and Health Effects Of Edcsmentioning

confidence: 99%

“…It was found that low concentrations of levonorgestrel and its fractions caused a reduction in pregnancy maintenance in some aquatic species and humans. 32 Also, it was found that alkylphenol (nonylphenol and oxylphenol) and peruoroalkyl substance exposure in women is associated with endometrial (the most common gynecological cancer in the United States) and breast cancer development. 33,34 Exposure can also aggravate some diseases such as COVID-19, where some biological pathways may be dysregulated by EDCs and function as contributors to COVID-19 severity, additionally increasing the side effects of the infection.…”

Section: Environmental and Health Effects Of Edcsmentioning

confidence: 99%

Environmental persistence, detection, and mitigation of endocrine disrupting contaminants in wastewater treatment plants – a review with a focus on tertiary treatment technologies

Rodríguez-Hernández

Araújo

López-Pacheco

et al. 2022

Environ. Sci.: Adv.

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“…Therefore, LNG shows environmental persistence because natural conditions do not completely remove this substance. For instance, LNG is not removed by solar radiation at wavelengths close to 320 nm, and even energy radiation (UVC-265) reduces only 80% of this substance [9]. Therefore, more complex photodegradation should be applied for its removal in treatment plants.…”

Section: Introductionmentioning

confidence: 99%

Assessment of Levonorgestrel Leaching in a Landfill and Its Effects on Placental Cell Lines and Sperm Cells

Ríos-Sossa

García-Londoño

Gil-Ramírez

et al. 2022

Water

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The Buenavista landfill is located east of the city of Medellín, but it has a slope steeper than 30% and is less than 600 m away from the Piedras River, possibly influencing the quality of the drinking water in the city. Many complex residues are disposed of in this landfill, including pharmaceuticals and personal care products (PPCPs) such as levonorgestrel (LNG), which may reach water bodies via runoff and leaching. We assessed the levels of LNG in the effluent of an upflow anaerobic sludge blanket (UASB) reactor from the Buenavista landfill by uHPLC–DAD, as well as the endocrine disruptor effect of LNG on placental cell lines (BeWo) and human sperm cells. Additionally, the potential leaching of LNG was assayed under laboratory conditions using soil layers that were sampled from the Buenavista landfill. LNG was detected at levels of 315 μg·L−1 in the effluents of the UASB reactor. Thus, the UASB reactor is not an efficient treatment method for the removal of recalcitrant pollutants. Additionally, we found that a layer of soil used as a cover material may adsorb more than 90% of LNG pollutants, but small amounts may still be leached, which means that a cover material is not a strong enough barrier to fully prevent the leaching of LNG. Finally, our results show that the leachate fraction decreased the levels of β-human chorionic gonadotropin, but not sperm motility or viability. Thus, leached LNG could trigger reproduction disorders, but further studies should be carried out to investigate its potential effects in more detail.

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Assessment of endocrine disruptor effects of levonorgestrel and its photoproducts: Environmental implications of released fractions after their photocatalytic removal

Cited by 22 publications

References 32 publications

Research on Dynamic Assessment System of Composite Fault Risk of Transmission Line Based on Blockchain Energy

Research on Dynamic Assessment System of Composite Fault Risk of Transmission Line Based on Blockchain Energy

Environmental persistence, detection, and mitigation of endocrine disrupting contaminants in wastewater treatment plants – a review with a focus on tertiary treatment technologies

Assessment of Levonorgestrel Leaching in a Landfill and Its Effects on Placental Cell Lines and Sperm Cells

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