Assessment of Executive and Cognitive Functions in Children with Restless Sleep Disorder: A Pilot Study

DelRosso, Lourdes M.; Vega-Flores, Germán; Ferri, Raffaele; Mogavero, Maria Paola; Diamond, Adele

doi:10.3390/brainsci12101289

Cited by 7 publications

(4 citation statements)

References 54 publications

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“…It has already been reported that, in healthy adult controls, these movements correlate positively with sleep stage N1 percentage, arousal index, sleep stage shifts, and negatively with sleep stage N3 [ 18 ]. It has also been reported that LMM, which characterizes a recently introduced pediatric sleep-related movement disorder called restless sleep disorder [ 35–37 ], might be frequent in children with RLS [ 38 ] and is associated with important clinical consequences, such as excessive daytime sleepiness and decreased quality of life [ 17 ], or cognitive functions, such as selective attention [ 39 ].…”

Section: Discussionmentioning

confidence: 99%

Large muscle group movements during sleep in restless leg syndrome: neurophysiological and clinical implications

Mogavero,

Congiu,

Lanza

et al. 2024

Sleep

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Study objectives Recently, criteria have been drawn up for Large Muscle group Movements during sleep (LMM), defined as movements lasting for 3-45 seconds in adults, which are often accompanied by changes in sleep stage, arousals, and increases in heart rate. The aim of this study was to characterize LMM in RLS, in order to better evaluate their impact on the neurophysiology of the disorder and, therefore, the possible clinical implications. Methods Consecutive, drug-free patients diagnosed with RLS and controls, aged 18 years or more, were retrospectively enrolled. Leg movement activity – short-interval (SILMS), periodic (PLMS) and isolated (ISOLMS) leg movements during sleep – and LMM were detected and scored. Results One-hundred patients and 67 controls were recruited. All movement measures were significantly higher in RLS. A significant positive correlation was found between LMM and ISOLMS index but not PLMS index in both groups. LMM index showed a significant negative correlation with total sleep time, sleep efficiency, and percentage of sleep stages N3 and R, as well as a significant positive correlation with number of awakenings, and percentage of sleep stages N1 and N2 only in patients with RLS. No significant correlation was found for either LMM or PLMS index and RLS severity. Conclusions Different types of movements, including SILMS, ISOLMS, and LMM, play somewhat distinct roles in sleep neurophysiology in RLS. Notably, LMM, a newly recognized category of movements, demonstrate associations with sleep architecture instability and fragmentation, arousals, and awakenings, suggesting potential clinical implications.

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Section: Discussionmentioning

confidence: 99%

Large muscle group movements during sleep in restless leg syndrome: neurophysiological and clinical implications

Mogavero,

Congiu,

Lanza

et al. 2024

Sleep

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“…This study is an important contribution to the literature to demonstrate a high prevalence of restless sleep disorder in children with sleep‐related epilepsy, associated with an increased number of LMM and frequent LMM‐associated nocturnal awakenings. It was recently shown that RSD affects neurocognitive and executive functions in children, resulting in poor school performance or behavioural problems (DelRosso, Vega‐Flores et al, 2022b). As restless sleep is highly prevalent in these children, they are often referred to a sleep centre to assess sleep disruption and to rule out nocturnal seizures.…”

Section: Discussionmentioning

confidence: 99%

Restless sleep disorder in children with epileptic and non‐epileptic nocturnal attacks

Şenel

Tunalı

Karadeniz

et al. 2023

Journal of Sleep Research

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SummaryRestless sleep disorder (RSD) is an important sleep disorder characterised by the presence of frequent large muscle movements (LMM) during sleep, which may be comorbid to other conditions/diseases. In this study, we investigated the frequency and the characteristics of RSD among children who were evaluated by polysomnography (PSG) due to epileptic and non‐epileptic nocturnal attacks. We analysed consecutively children younger than 18 years who were referred for PSG recording due to abnormal motor activities during sleep. The diagnosis of nocturnal events as sleep‐related epilepsy was made based on the current consensus. Patients who were referred with suspicion of sleep‐related epilepsy, but who were diagnosed to have non‐epileptic nocturnal events and children with a definitive diagnosis of NREM sleep parasomnias were also enrolled. Sixty‐two children were analysed in this study (17 children with sleep‐related epilepsy, 20 children with NREM parasomnia, and 25 children with nocturnal events not otherwise classified [neNOS]). The mean number of LMM, LMM index, LMM‐associated with arousal and its index were all significantly higher in children with sleep‐related epilepsy. Restless sleep disorder was present in 47.1% of patients with epilepsy, 25% of patients with parasomnia, and in 20% of patients with neNOS. The mean A3 duration and the A3 index were higher in children with sleep‐related epilepsy and RSD compared with those with parasomnia and restless sleep disorder. Patients with RSD had lower ferritin levels than those without RSD in all subgroups. Our study demonstrates a high prevalence of restless sleep disorder in children with sleep‐related epilepsy, associated with an increased cyclic alternating pattern.

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“…Más de la mitad de los autores (61,3%) sugieren que la incidencia de los trastornos del sueño difiere en función de los ámbitos de estudio en el contexto escolar: matemáticas y ciencias (15.4%) por ejemplo Brockmann et al (2015), Gatica et al (2017), etc., lenguaje (11.5%) por ejemplo Bennett et al (2018), Brockmann et al (2015, etc., y educación física (3.8%) por ejemplo Bennett et al (2018), Cladellas i Pros et al (2011, etc. Por otra parte los trastornos no respiratorios del sueño, disminuyen la atención (17.6%) por ejemplo Gómez y Genzel (2020), del Rosso et al (2022, etc., la memoria de trabajo así como la declarativa (11.8%), por ejemplo, Smith et al (2020), Williamson et al (2020), etc. En definitiva, sueño y rendimiento académico están relacionados; un sueño correcto tanto en calidad como en cantidad, así como unos hábitos del sueño adecuados que propicien su correcta higiene, conllevan mejora una mejora del rendimiento académico, reflejada tanto en los procesos cognitivos subyacentes como en las calificaciones. Al contrario, un sueño alterado influye en la disminución del rendimiento académico, así como en los procesos de aprendizaje.…”

Section: Afinidades Y Discrepancias Entre Los Documentos Analizadosunclassified

Sueño y Rendimiento Académico en la Educación Primaria. Una Revisión Sistématica

Gracia Bernad,

Sastre-Riba,

Viana-Sáenz

2024

Rev. Psicol. Educ

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Sueño Rendimiento académicoAlteraciones del sueño Educación Primaria RESUMENAntecedentes: El sueño es vital para el ser humano, cumple diversas funciones para la reparación neuronal, metabólica y reorganización de circuitos. Es importante conocer cómo afecta a los escolares dado que su cantidad y calidad influyen en la motivación, atención, memoria y logros académicos. La investigación es aún escasa y con resultados discrepantes sobre las áreas cerebrales involucradas, consecuencias, o cómo intervenir ante hábitos de sueño inadecuados, aceptándose que un sueño inadecuado comporta peor rendimiento académico. El Objetivo General es conocer la influencia del sueño en el rendimiento académico en Educación Primaria; los objetivos específicos son: conocer el trastorno de sueño más común en escolares, el más influyente en el rendimiento, y los instrumentos para su estudio. Método: se realiza una revisión sistemática de publicaciones científicas aplicando criterios de búsqueda, vaciado y análisis del contenido. Resultados: el sueño se relaciona con procesos cognitivos de atención focalizada y consolidación de memoria, así como con el rendimiento académico, especialmente en matemáticas, ciencias, lenguaje y deporte. Conclusión-discusión: muestra la base neurológica del sueño, los trastornos asociados y su relación con el rendimiento, discutiendo la necesidad de promover hábitos de sueño sanos atendiendo.

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Assessment of Executive and Cognitive Functions in Children with Restless Sleep Disorder: A Pilot Study

Cited by 7 publications

References 54 publications

Large muscle group movements during sleep in restless leg syndrome: neurophysiological and clinical implications

Large muscle group movements during sleep in restless leg syndrome: neurophysiological and clinical implications

Restless sleep disorder in children with epileptic and non‐epileptic nocturnal attacks

Sueño y Rendimiento Académico en la Educación Primaria. Una Revisión Sistématica

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