Assessment of exposure of gas station attendants in Sri Lanka to benzene, toluene and xylenes

Scheepers, Paul T.J.; Werdt, Laurie de; Dael, Maurice van; Anzion, Rob; Vanoirbeek, Jeroen; Duca, Radu Corneliu; Creta, Matteo; Godderis, Lode; Warnakulasuriya, D. T. D.; Devanarayana, Niranga Manjuri

doi:10.1016/j.envres.2019.108670

Cited by 26 publications

(13 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The safe duration of toluene in the Osowilangun shoe home industry does not reach 8 hours even though not all places have a toluene concentration of more than 20 ppm. This is in accordance with Scheepers research entitled Assessment of Exposure of Gas Station Attendants in Sri Lanka to Benzene, Toluene and Xylene (BTX) with a reduction in work duration to 40 hours/week can reduce BTX concentrations in workers' blood to safe limits 9 . Repeated toluene exposure can cause cognitive impairment in mice 10 .…”

Section: Resultssupporting

confidence: 86%

Correlation of Toluene Safe Duration (Hours/Day) and Glutathione Concentration, Malondialdehyde and Neurotoxic Symptoms in Osowilangun Shoe Home Industry Workers

Ningrum

Tualeka

Jalaludin

et al. 2020

IJFMT

View full text Add to dashboard Cite

Introduction: Exposure of toluene can cause a decrease in glutathione concentration, increase in malondialdehyde and neurotoxic symptoms. The safe duration of toluene in hours/day for each person can vary. The purpose of this study is to determine the relationship between the safe duration of toluene (hours/ day) with the concentration of glutathione, malondialdehyde and neurotoxic symptoms in Osowilangun shoe home industry workers.Methods: This research was observational with quantitative approach and cross-sectional design. The sampling technique used was accidental sampling with 25 respondents. The variables studied were safe toluene duration (hours/day), glutathione concentration, malondialdehyde concentration, and neurotoxic symptoms. Data were analyzed using Pearson and Phi correlation. Result:The average of safe duration was 1,489 hours/day, glutathione concentration was 58,349 µg/L, and malondialdehyde was 7,847 MU. As many as 11 out of 14 workers experienced neurotoxic symptoms. The relationship between safe duration (hours/day) with glutathione concentration (r=0.139) and malondialdehyde (r=-0.146) was very weak. While, the relationship between safe duration (hours/day) and neurotoxic symptoms was weak (φ=-0.223). Conclusion:The relationship between safe duration in hours/day with glutathione concentration and malondialdehyde was very weak, while relationship with neurotoxic symptoms was weak.

show abstract

Section: Resultssupporting

confidence: 86%

Correlation of Toluene Safe Duration (Hours/Day) and Glutathione Concentration, Malondialdehyde and Neurotoxic Symptoms in Osowilangun Shoe Home Industry Workers

Ningrum

Tualeka

Jalaludin

et al. 2020

IJFMT

View full text Add to dashboard Cite

show abstract

“…Hence, more research is needed to monitor the adverse effects and cancer occurrence of occupational exposure to benzene and other possible genotoxic/carcinogenic chemicals such as PM and PAHs at gas stations. The levels of VOCs, such as BTEX in fuel vapor, have been measured both in the working environment and in the biological fluids of the gasoline station attendants in various countries, and some of these measured values have exceeded the limit values recommended by American Conference of Governmental Industrial Hygienists (ACGIH) and National Institute for Occupational Safety & Health (NIOSH) (Bahrami et al, 2007;Raghavan and Basavaiah 2005;Scheepers et al, 2019;Soltanpour et al, 2021). Several studies have detected higher levels of metabolites of these hydrocarbons, such as trans trans-muconic acid (t,t-MA), in blood or urine samples of these workers than in controls (Bahrami et al, 2007;Costa et al, 2016;Geraldino et al, 2021;Hassan et al, 2013).…”

Section: Discussionmentioning

confidence: 99%

Assessment of genotoxicity biomarkers in gasoline station attendants due to occupational exposure

Elkama,

Şentürk,

Karahalil

2024

Toxicol Ind Health

View full text Add to dashboard Cite

Gasoline station attendants are exposed to numerous chemicals that might have genotoxic and carcinogenic potential, such as benzene in fuel vapor and particulate matter and polycyclic aromatic hydrocarbons in vehicle exhaust emission. According to IARC, benzene and diesel particulates are Group 1 human carcinogens, and gasoline has been classified as Group 2A “possibly carcinogenic to humans.” At gas stations, self-service is not implemented in Turkey; fuel-filling service is provided entirely by employees, and therefore they are exposed to those chemicals in the workplace during all working hours. Genetic monitoring of workers with occupational exposure to possible genotoxic agents allows early detection of cancer. We aimed to investigate the genotoxic damage due to exposures in gasoline station attendants in Turkey. Genotoxicity was evaluated by the Comet, chromosomal aberration, and cytokinesis-block micronucleus assays in peripheral blood lymphocytes. Gasoline station attendants ( n = 53) had higher tail length, tail intensity, and tail moment values than controls ( n = 61). In gasoline station attendants ( n = 46), the frequencies of chromatid gaps, chromosome gaps, and total aberrations were higher compared with controls ( n = 59). Increased frequencies of micronuclei and nucleoplasmic bridges were determined in gasoline station attendants ( n = 47) compared with controls ( n = 40). Factors such as age, duration of working, and smoking did not have any significant impact on genotoxic endpoints. Only exposure increased genotoxic damage in gasoline station attendants independently from demographic and clinical characteristics. Occupational exposure-related genotoxicity risk may increase in gasoline station attendants who are chronically exposed to gasoline and various chemicals in vehicle exhaust emissions.

show abstract

“…Scheepers, et al (16) evidenciaron que la exposición de 2,24 ppm pero la exposición entre 8 y 16 horas son perjudiciales; Liu et al (7) al contrario de los anterior autores afirman que la concentración toxica se encuentra a cantidades inferiores de 0,25 ppm, no obstante, las alteraciones sanguinas se producen en la exposición mayor a 12 meses, y finalmente Chaiklieng et al (2) describe un rango de concentración toxica, el cual comprende entre 0.03 a 65.71 ppm, ya sea a más de 8 horas diarias o por más de 6 meses.…”

Section: Discussionunclassified

“…De igual manera Scheepers et al (16) concluyeron que la reducción de horas de trabajo aproximadamente a 40 horas semanales, disminuye la intoxicación crónica por benceno por ende los efectos colaterales serán menores y se protegerá el bienestar de los despachadores de combustible.…”

Section: Discussionunclassified

Chronic hematologic manifestations of benzene exposure in fuel dispatchers

Ochoa

Bojorque

Torres

et al. 2022

Salud, Ciencia y Tecnología

View full text Add to dashboard Cite

Introducción: El benceno es un hidrocarburo aromático considerado como cancerígeno por su alta toxicidad, aunque en los últimos años su exposición ha disminuido, sin embargo, no ha sido suficiente para prevenir complicaciones. La exposición crónica en concentraciones superiores o igual a 1 ppm por un periodo superior a 8 horas diarias durante 10 años constante o cuando su exposición supera los 10 ppm durante 1 año existe riesgo de desarrollar trastornos hematológicos. Objetivo: Describir las manifestaciones hematológicas crónicas por exposición a Benceno en despachadores de combustible.Método: Se realizó una revisión narrativa, recopilando información desde enero 2000, hasta noviembre de 2022 en base de datos científicas como Pubmed, Enviromental Pollution, Dialnet, SAGE, Taylor and Francis, Springerlink, Science Direct, Scielo; empleando palabras claves. Resultados: Las manifestaciones hematológicas que se desarrollan tras la exposición crónica de benceno en cualquier concentración se encuentran la leucemia linfoide, linfoma no Hodgkin, leucemia mieloide aguda, síndrome mielodisplasico, leucemia mieloide crónica, mieloma múltiple, leucemia mieloide crónica y anemia aplásica. Conclusiones: Existen diversas manifestaciones tras la exposición crónica de benceno destacando leucemia linfática crónica, linfoma no Hodgkin, leucemia mieloide aguda o crónica, síndrome mielodisplasico y mieloma múltiple; es por ello que se recomienda hacer controles médicos anuales y la aplicación de estrategias que reduzcan el tiempo de exposición laboral, de forma que permitan diagnosticar y prevenir enfermedades hematológicas ya que actualmente no existen normativas de prevención que garanticen el bienestar de los despachadores.

show abstract

Assessment of exposure of gas station attendants in Sri Lanka to benzene, toluene and xylenes

Cited by 26 publications

References 33 publications

Correlation of Toluene Safe Duration (Hours/Day) and Glutathione Concentration, Malondialdehyde and Neurotoxic Symptoms in Osowilangun Shoe Home Industry Workers

Correlation of Toluene Safe Duration (Hours/Day) and Glutathione Concentration, Malondialdehyde and Neurotoxic Symptoms in Osowilangun Shoe Home Industry Workers

Assessment of genotoxicity biomarkers in gasoline station attendants due to occupational exposure

Chronic hematologic manifestations of benzene exposure in fuel dispatchers

Contact Info

Product

Resources

About