Assessment of exposure to perfluoroalkyl substances (PFASs) in dogs by fur analysis

Makowska, Krystyna; Martín, Julia; Rychlik, Andrzej; Aparicio, Irene; Santos, Juan Luís; Alonso, Esteban; Gonkowski, Sławomir

doi:10.1016/j.envpol.2021.117435

Cited by 9 publications

(6 citation statements)

References 68 publications

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“…Moreover, hair samples are easy to store and inexpensive to transport, even over long distances. Simultaneously, previous studies have shown that hair analysis is fully usable for monitoring exposure to various environmental endocrine disruptors for both humans [35,[37][38][39] and dogs [26,27]. Moreover, it is known that the results obtained from hair analysis are similar-with regard to sensitivity and reliability-to the results obtained by studying blood or urine [40].…”

Section: Introductionmentioning

confidence: 92%

“…It should be pointed out that, contrary to human medicine, the role of BPA as a toxic and disease agent in veterinary medicine has been marginalised until recently. Despite this, it is known that domestic animals, especially dogs and cats, which live together with humans in the same conditions, are exposed to similar environmental pollutants as humans [15,26,27]. Knowledge of both pet animal exposure to BPA and the participation of this substance in pathological processes in such animals is relatively scarce.…”

Section: Introductionmentioning

confidence: 99%

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Hair Sample Analysis as a Method of Monitoring Exposure to Bisphenol A in Dogs

Makowska

Martín

Rychlik

et al. 2022

IJERPH

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Bisphenol A (BPA) is an organic substance widely used in the plastics industry. It penetrates food and environment and, as an endocrine disruptor, has detrimental effects on human organisms. Pet animals, which live in the immediate vicinity of humans, are also exposed to BPA; however, knowledge regarding the exposure of dogs to this substance is extremely scarce. This is the first study in which hair analysis has been used to biomonitor BPA in 30 dogs using liquid chromatography and tandem mass spectrometry techniques. The presence of BPA in concentration levels above the method detection limit (1.25 ng/g) was noted in 93.33% of samples. BPA concentration levels were found to range from 7.05 ng/g to 436 ng/g (mean 81.30 ng/g). Statistically significant differences in BPA concentration levels were found between animals with physiological weight and animals with abnormal weight (skinny and obese). In turn, differences between males and females, as well as between young, middle-aged and old dogs, were not statistically significant. The obtained results have clearly shown that hair analysis is a useful method to evaluate the exposure of dogs to BPA. This study also confirmed that dogs are exposed to BPA to a large extent, and this substance may play a role as a pathological factor in this animal species. However, many aspects connected to the influence of BPA on canine health status are unclear and need further study.

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Section: Introductionmentioning

confidence: 92%

Section: Introductionmentioning

confidence: 99%

Hair Sample Analysis as a Method of Monitoring Exposure to Bisphenol A in Dogs

Makowska

Martín

Rychlik

et al. 2022

IJERPH

Self Cite

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“…A variety of EDCs (e.g., PCBs, organochlorine pesticides, dioxin-related compounds, phthalates, BPA, PBDEs, and PFASs) have been reported in cat and dog tissues, including genitals, adipose tissue, blood, urine, and fur [16,108,109,114,152,153]. However, in comparison with the large number of studies regarding EDCs and the health status of humans and wildlife, published studies on EDCs' adverse effects in cats and dogs are scarce.…”

Section: Health Effects Of Exposure To Edcs In Domestic Petsmentioning

confidence: 99%

Endocrine-Disrupting Chemicals and Their Effects in Pet Dogs and Cats: An Overview

Pocar

Grieco

Aidos

et al. 2023

Animals

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Over the past few decades, several pollutants classified as environmental endocrine-disrupting chemicals (EDCs) have become a matter of significant public health concern. Companion animals play a major role in human society, and pet ownership is substantially increasing worldwide. These intimate human–pet relationships imply sharing much of the same environment, thus including exposure to similar levels of EDCs in daily routine. Here, we review the current knowledge on the sources and routes of exposure to EDCs in domestic indoor and outdoor environments and discuss whether endocrine disruption is a health concern in pets. We summarize the phenomenon of endocrine disruption, providing examples of EDCs with a known impact on dog and cat health. Then, we propose an overview of the literature on the adverse effects of EDCs in domestic pets, with a special focus on the health of reproductive and thyroid systems. Finally, we explore the potential role of companion animals as unintentional sentinels of environmental exposure to EDCs and the implications for public health risk assessment in a “shared risk” scenario. Overall, this review supports the need for an integrated approach considering humans, animals, and the environment as a whole for a comprehensive assessment of the impact of EDCs on human and animal health.

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“…A recent study found more than 70 organic contaminants in pet hair samples, 7 as well as perfluorinated chemicals. 8 Yang et al found that enrichment factors of PAHs and OPEs in pet hair were higher than those in indoor dust, 9 suggesting that exposure routes from pet hair should not be ignored when assessing the health risk from indoor pollutants. This concern is intensified with the increasing population of pet owners in recent years 10 and pets have been proposed to be sentinels of indoor contamination.…”

Section: Introductionmentioning

confidence: 99%