Assessment of eye length changes in accommodation using dynamic extended-depth OCT

Chang, Yeon S.; Liu, Keke; Freitas, Carolina De; Pham, Alex; Cabot, Florence; Williams, Siobhan; Adre, Ethan; Gregori, Giovanni; Ruggeri, Marco; Yoo, Sonia H.; Ho, Arthur; Parel, Jean Marie; Manns, Fabrice

doi:10.1364/boe.8.002709

Cited by 8 publications

(11 citation statements)

References 26 publications

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“…The latter is in controversy with the report by Faria-Correia et al [ 49 ]. In any case, the grading of presbyopia and cataracts through AS-OCT seems to be a promising technology, not only because of the OLD measure, but also due to the possibility to measure the dynamic changes of the crystalline lens during accommodation [ 55 ].…”

Section: Objective Technologies For Lens Evaluationmentioning

confidence: 99%

From Presbyopia to Cataracts: A Critical Review on Dysfunctional Lens Syndrome

Fernández¹,

Rodríguez‐Vallejo²,

Martínez³

et al. 2018

Journal of Ophthalmology

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Dysfunctional lens syndrome (DLS) is a term coined to describe the natural aging changes in the crystalline lens. Different alterations in the refractive properties and transparency of the lens are produced during the development of presbyopia and cataract, such as changes in internal high order aberrations or an increase in ocular forward scattering, with a potentially significant impact on clinical measures, including visual acuity and contrast sensitivity. Objective technologies have emerged to solve the limits of current methods for the grading of the lens aging, which have been linked to the DLS term. However, there is still not a gold standard or evidence-based clinical guidelines around these new technologies despite multiple research studies have correlated their results with conventional methods such as visual acuity or the lens opacification system (LOCS), with more scientific background around the ocular scattering index (OSI) and Scheimpflug densitometry. In either case, DLS is not a new evidence-based concept that leads to new knowledge about crystalline lens aging but it is a nomenclature change of two existing terms, presbyopia and cataracts. Therefore, this term should be used with caution in the scientific peer-reviewed literature.

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Section: Objective Technologies For Lens Evaluationmentioning

confidence: 99%

From Presbyopia to Cataracts: A Critical Review on Dysfunctional Lens Syndrome

Fernández¹,

Rodríguez‐Vallejo²,

Martínez³

et al. 2018

Journal of Ophthalmology

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“…In Ref. [26], the light-distortion correction on the whole eye was achieved by dividing the [20]; D, J, Corrected images by the method in Ref. [25]; E, K, Corrected images by the method in Ref.…”

Section: Comparative Imagingmentioning

confidence: 99%

“…[20]. Chang et al realized the whole-eye imaging through SD-OCT, and spliced the OCT images to study the parameter changes of each part in the eye after myopia [26]. However, the thickness and curvature of each part of the eye were calculated on the images corrected just by dividing the average refractive index of the whole eye, leading to dramatic measurement errors.…”

Section: Introductionmentioning

confidence: 99%

Correction of refractive distortion in whole‐eye optical coherence tomography imaging of the mouse eye

Tan

Qiu

Ding

et al. 2022

Journal of Biophotonics

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Optical coherence tomography (OCT) is an imaging modality that acquires high‐resolution cross‐sectional images of living tissues and it has become the standard in ophthalmological diagnoses. However, most quantitative morphological measurements are based on the raw OCT images which are distorted by several mechanisms such as the refraction of probe light in the sample and the scan geometries and thus the analysis of the raw OCT images inevitably induced calculation errors. In this paper, based on Fermat's principle and the concept of inverse light tracing, image distortions due to refraction occurred at tissue boundaries in the whole‐eye OCT imaging of mouse by telecentric scanning were corrected. Specially, the mathematical correction models were deducted for each interface, and the high‐precision whole‐eye image was recovered segment by segment. We conducted phantom and in vivo experiments on mouse and human eyes to verify the distortion correction algorithm, and several parameters of the radius of curvature, thickness of tissues and error, were calculated to quantitatively evaluate the images. Experimental results demonstrated that the method can provide accurate and reliable measurements of whole‐eye parameters and thus be a valuable tool for the research and clinical diagnosis.

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“…However, due to the refractive power of the anterior segment a light beam can not be focused on both the anterior segment and the retina simultaneously, high lateral resolution whole eye segments images can not be obtained. Nowadays, extended-depth SD-OCT for whole eye segment imaging is widely used in eye parameter detecting and examination of ocular accommodation [43][44][45].…”

Section: Limitations Of Traditional Ophthalmologic Oct Imagingmentioning

confidence: 99%

Whole Eye Optical Coherence Tomography Imaging

2018

ABBSR

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OCT Techniques for Whole Eye Segment ImagingFor whole eye segment imaging, several full-range and combinationimage techniques were developed for imaging depth extension in SD-OCT and high quality swept light source were investigated in SS-OCT [11][12][13][14][15][16][17][18][19][20][21][22][23][24]. SD-OCT for Whole Eye ImagingIn SD-OCT system, the imaging depth is restricted by the Hermitian symmetry of Fourier transformation of the real-valued spectral interferogram and the intrinsic limitation of spectral resolution of the Abstract Many eye diseases will affect the shape and dimensions of the whole eye. For examination of ocular accommodation and pathological changes caused by these diseases, high resolution imaging of the whole eye segments OCT system is needed. However, limited by the imaging depth, traditional Fourier Domain Optical Coherence Tomography (FD-OCT) can't be used for real time whole eye segment imaging. In recent years, techniques for depth extended FD-OCT system especially for whole eye segment imaging has been developed. Application on eye parameters measurement and eye accommodation studies were successfully performed. In this paper, both of whole eye FD-OCT techniques and their application were reviewed. Potential clinical application of these techniques may be in the detection of the pathological changes of the whole eye, and whole eye segment FD-OCT system also provides a powerful imaging method for ophthalmic research, such as accommodation, ocular growth, and biometry of the eye.

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Assessment of eye length changes in accommodation using dynamic extended-depth OCT

Cited by 8 publications

References 26 publications

From Presbyopia to Cataracts: A Critical Review on Dysfunctional Lens Syndrome

From Presbyopia to Cataracts: A Critical Review on Dysfunctional Lens Syndrome

Correction of refractive distortion in whole‐eye optical coherence tomography imaging of the mouse eye

Whole Eye Optical Coherence Tomography Imaging

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