Assessment of Fetal Growth by Customized Growth Charts

Gaillard, Romy; Jaddoe, Vincent W. V.

doi:10.1159/000361055

Cited by 13 publications

(10 citation statements)

References 48 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These ultrasound examinations were used to establish gestational age and to assess fetal growth patterns [35, 36]. These methods have previously been described in detail [37–39].…”

Section: Measurementsmentioning

confidence: 99%

The Generation R Study: design and cohort update 2017

et al. 2016

View full text Add to dashboard Cite

The Generation R Study is a population-based prospective cohort study from fetal life until adulthood. The study is designed to identify early environmental and genetic causes and causal pathways leading to normal and abnormal growth, development and health from fetal life, childhood and young adulthood. This multidisciplinary study focuses on several health outcomes including behaviour and cognition, body composition, eye development, growth, hearing, heart and vascular development, infectious disease and immunity, oral health and facial growth, respiratory health, allergy and skin disorders of children and their parents. Main exposures of interest include environmental, endocrine, genomic (genetic, epigenetic, microbiome), lifestyle related, nutritional and socio-demographic determinants. In total, 9778 mothers with a delivery date from April 2002 until January 2006 were enrolled in the study. Response at baseline was 61%, and general follow-up rates until the age of 10 years were around 80%. Data collection in children and their parents includes questionnaires, interviews, detailed physical and ultrasound examinations, behavioural observations, lung function, Magnetic Resonance Imaging and biological sampling. Genome and epigenome wide association screens are available. Eventually, results from the Generation R Study contribute to the development of strategies for optimizing health and healthcare for pregnant women and children.

show abstract

“…These ultrasound examinations were used to establish gestational age and to assess fetal growth patterns [35, 36]. These methods have previously been described in detail [37–39].…”

Section: Measurementsmentioning

confidence: 99%

The Generation R Study: design and cohort update 2017

et al. 2016

View full text Add to dashboard Cite

show abstract

“…It is well-established that newborns born SGA or LGA may be both constitutionally or pathologically small or large for their gestational age [39]. It has been suggested that newborns who are pathologically small or large for their gestational age due to abnormal fetal growth have increased risks of morbidity and mortality, as compared to those newborns who are constitutionally small or large for their gestational age [39].…”

Section: Interpretation Of Main Findingsmentioning

confidence: 99%

Second and third trimester fetal ultrasound population screening for risks of preterm birth and small-size and large-size for gestational age at birth: a population-based prospective cohort study

Erkamp

Voerman

Steegers

et al. 2020

BMC Med

Self Cite

View full text Add to dashboard Cite

Background: Preterm birth, small size for gestational age (SGA) and large size for gestational age (LGA) at birth are major risk factors for neonatal and long-term morbidity and mortality. It is unclear which periods of pregnancy are optimal for ultrasound screening to identify fetuses at risk of preterm birth, SGA or LGA at birth. We aimed to examine whether single or combined second and third trimester ultrasound in addition to maternal characteristics at the start of pregnancy are optimal to detect fetuses at risk for preterm birth, SGA and LGA. Methods: In a prospective population-based cohort among 7677 pregnant women, we measured second and third trimester estimated fetal weight (EFW), and uterine artery pulsatility and umbilical artery resistance indices as placenta flow measures. Screen positive was considered as EFW or placenta flow measure < 10th or > 90th percentile. Information about maternal age, body mass index, ethnicity, parity, smoking, fetal sex and birth outcomes was available from questionnaires and medical records. Screening performance was assessed via receiver operating characteristic (ROC) curves and area under the curve (AUC) along with sensitivity at different false-positive rates.

show abstract

“…As appropriate as it may appear, this particular definition is impractical due to the challenge of assessing the genetic potential of a certain individual. Newer diagnostic tools allowing the longitudinal evaluation of fetal growth in a noninvasive fashion and the current development of fetal growth trajectories have been proposed as an alternative to assess growth potential and IUGR (127,403). In this regard, premature infants represent an interesting group since they are usually born small but may be appropriate for their gestational age.…”

Section: B Defining Birth Weightmentioning

confidence: 99%

In Utero Origins of Hypertension: Mechanisms and Targets for Therapy

Morton

Cooke

Davidge³

2016

Physiological Reviews

View full text Add to dashboard Cite

The developmental origins of health and disease theory is based on evidence that a suboptimal environment during fetal and neonatal development can significantly impact the evolution of adult-onset disease. Abundant evidence exists that a compromised prenatal (and early postnatal) environment leads to an increased risk of hypertension later in life. Hypertension is a silent, chronic, and progressive disease defined by elevated blood pressure (>140/90 mmHg) and is strongly correlated with cardiovascular morbidity/mortality. The pathophysiological mechanisms, however, are complex and poorly understood, and hypertension continues to be one of the most resilient health problems in modern society. Research into the programming of hypertension has proposed pharmacological treatment strategies to reverse and/or prevent disease. In addition, modifications to the lifestyle of pregnant women might impart far-reaching benefits to the health of their children. As more information is discovered, more successful management of hypertension can be expected to follow; however, while pregnancy complications such as fetal growth restriction, preeclampsia, preterm birth, etc., continue to occur, their offspring will be at increased risk for hypertension. This article reviews the current knowledge surrounding the developmental origins of hypertension, with a focus on mechanistic pathways and targets for therapeutic and pharmacologic interventions.

show abstract

Assessment of Fetal Growth by Customized Growth Charts

Cited by 13 publications

References 48 publications

The Generation R Study: design and cohort update 2017

The Generation R Study: design and cohort update 2017

Second and third trimester fetal ultrasound population screening for risks of preterm birth and small-size and large-size for gestational age at birth: a population-based prospective cohort study

In Utero Origins of Hypertension: Mechanisms and Targets for Therapy

Contact Info

Product

Resources

About