The present study highlights the evolution, the progress and the prospects of future practices of water reuse in the world. The objective was to produce a comprehensive timeline on the global evolution and progress of water reuse. This was achieved through the analysis of the state of the art on the subject. The present study is a qualitative research, where three aspects have been considered to highlight the global evolution of water reuse: i) Regulations, Standards, Criteria or Guidelines (RSCG); ii) Indirect Potable Reuse Projects (IPR); and iii) Direct Potable Reuse Projects (DPR). The study focused on both legal and practical aspects of water reuse and considered 3 timelines in the context of RSCG, IPR and DPR: 29 RSCG instruments, institutionalized from 1918 to 2020, where only 4 instruments were solely dedicated to drinking water reuse; 10 IPR projects; 5 DPR projects. To achieve good, effective results, the regulatory framework must support the objectives of a structured water reuse policy in addition to guaranteeing legitimacy and maintaining public confidence. Integrated water and wastewater management, based on technological and scientific advances, has become a relevant aspect for implementation of more adequate measures by decision makers to address future global water challenges.