Assessment of health-related quality of life among adult patients with type 2 diabetes mellitus

Stanetić, Kosana; Račić, Maja; Kević, Vesna

doi:10.7251/bii1701032s

Cited by 3 publications

(3 citation statements)

References 20 publications

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“…Previous literature has confirmed the fact that a lower HbA1c level is associated with better QoL and, as this level increases, QoL deteriorates. 32 Previous literature reported that disease control among diabetic patients was one of the most important determinants of QoL. 33–35 Furthermore, checking glucose levels on a regular basis may be beneficial for glycemic control and may be a preventive factor for QoL.…”

Section: Discussionmentioning

confidence: 99%

The Health-Related Quality of Life of Patients with Type 2 Diabetes in Saudi Arabia

AbuAlhommos¹,

Alturaifi²,

Hamdhah³

et al. 2022

PPA

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Objective Diabetes mellitus (DM) is one of the most common chronic diseases in the world. Diabetes mellitus has a major effect on patients’ quality of life, especially when the patient has other comorbidities. Therefore, this study aims to assess the quality of life of type 2 diabetic patients in the Al-Ahsa region of Saudi Arabia. Methods This was a cross-sectional study, which was conducted from September 2020 to May 2021 on patients with type 2 diabetes mellitus in the Al-Ahsa region of Saudi Arabia. Inclusion criteria were patients diagnosed with T2DM and aged 18 years and older. The EQ-5D-5L tool was used in this study to measure the quality of life. Results A total of 321 patients with T2DM participated in the study. Only 8.4% of the study participants reported that their disease did not let them do their daily activities at all. The most commonly reported problems related to diabetes mellitus and its effect on patients’ quality of life were pain/discomfort (around 68.0% of the patients reported some sort of problems in this dimension), followed by mobility, and depression and anxiety. There was a significant difference between males and females in terms of their quality of life, specifically self-care, pain and discomfort, and depression and anxiety (p<0.05). Patients from different marital statuses, education levels, employment status, and duration of the disease showed a significant difference in quality of life, except for depression and anxiety (p>0.05). Conclusion Pain/discomfort, mobility, and depression/anxiety are the main problems that are affecting diabetic patients’ quality of life. Future studies are recommended to explore the effectiveness of patient tailored interventions to decrease the negative impact of these dimensions on patients’ quality of life.

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Section: Discussionmentioning

confidence: 99%

The Health-Related Quality of Life of Patients with Type 2 Diabetes in Saudi Arabia

AbuAlhommos¹,

Alturaifi²,

Hamdhah³

et al. 2022

PPA

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“…Diabetic neuropathy can also present with symptoms such as paresthesias, numbness, and tingling in the hands and feet, which can lead to a mix-up between vitamin B12 deficiency and diabetic peripheral neuropathy diagnosis [2]. Thus, early discovery of vitamin B12 deficiency could slow the progression of neurological damage, and if misdiagnosed as diabetic neuropathy, this vitamin B12 shortage could lead to permanent neurological impairment [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Assessment of Vitamin B12 Deficiency Caused by Metformin in Type II Diabetic Patients

Raghavan

2021

JPRI

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Metformin use over time reduces vitamin B12 levels, according to several studies, and its clinical manifestation can be mistaken as diabetic peripheral neuropathy. In order to investigate vitamin-B12 deficiency in type II diabetic patients with long-term metformin treatment, a link between vitamin B12 and peripheral neuropathy, and to evaluate the quality of life in (T2DM) patients, the current study was done. At Sree Balaji Medical College and Hospital's outpatient and inpatient departments, a prospective observational case-control research was done. The study included 35 healthy volunteers (controls) and 35 Type 2 diabetes patients who had been on metformin for more than six months (cases). Patients' venous blood samples were collected in K2 EDTA vacutainers and centrifuged at 1500 rpm for 10 minutes, settled plasma was transferred into cryo-vials, and parameters such as Vitamin-B12, HbA1c, and CBP were estimated and this is used to conduct the statistical analysis. The prevalence of blood vitamin B12 deficiency and borderline deficiency in T2DM patients is 20.5 percent, while the mean HbA1C values in our study T2DM subjects are 9.07 percent, indicating either poor diabetes control or poor metformin drug compliance. Vitamin B12 insufficiency was found in 83 percent of T2DM patients who had been using metformin for 1 to 10 years. The reliability test was used to assess their quality of life, and the results revealed that the study participants' quality of life was poor.

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“…Insulin therapy in diabetes can substantially affect the quality of life positively by reducing symptoms of high blood sugar, or negatively by increasing symptoms of low blood glucose. 8 The aim of the study was to investigate the risk of long-term use of Metformin induces Vitamin-B12 deficiency amongst Type II diabetic patients and evaluate their quality of life. The Objectives stand to determine the levels of Vitamin B12 in diabetic patients concerning control population, to Study the association between vitamin B12 and peripheral neuropathy and lastly assess their quality of life by using WHO-BREF scale.…”

Section: Introductionmentioning

confidence: 99%

Assessment of Metformin Induced Vitamin-B12 Deficiency amongst Type-II Diabetic Patients Vis-À-Vis Evaluating the Quality of Life

Reddy¹,

K²,

Madaboina³

et al. 2019

IJCMR

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Introduction:Metformin is the cornerstone medication in the management of Type 2 diabetes mellitus with estimates that it is prescribed to 120 million patients with diabetes around the world. Several studies reported that the long-term use of metformin lowers vitamin -B12 levels and its clinical manifestation can be misdiagnosed as diabetic peripheral neuropathy. Thereby, the present study was undertaken to assess the vitamin-b12 deficiency in type II Diabetic patients with long-term use of metformin, an association between vitamin B12 and peripheral neuropathy and evaluating the quality of life in (T2DM) patients. Material and Methods: A prospective observational casecontrol study was conducted at the outpatient and inpatient departments of RVM Hospital. Total 34 (controls) healthy volunteers and 34 (cases) Type 2 diabetes patients using metformin for more than six months were recruited for the study. Data was collected using designed profile form, structured questionnaires and venous blood samples were collected in K2 EDTA vacutainers from the patients and centrifuged at 1500 rpm for 10 minutes, settled plasma was transferred into cryovials, estimating the parameters such as Vitamin-B12, HbA1c and CBP. The statistical analysis was done using SPSS (v25) software. Results: The prevalence of serum vitamin B12 deficiency and borderline deficiency in T2DM patients is 20.5%, the mean HbA1C levels in our study T2DM subjects is < 9.07% which is showing either poor control of diabetes and lack of compliance with metformin medication. 83% of T2DM patients with 1-10 years of metformin use resulted in Vitamin-B12 deficiency. Conclusion: Vitamin-B12 deficiency and Borderline deficiency prevalence in Type II Diabetes patients was found to be slightly high in our study population when compared to control subjects. The reliability test was done to evaluate their quality of life which concludes that the quality of life was poor amongst the study participants. Considering the regular screening of vitamin-B12 as a cost factor, the peripheral smear can be done in T2DM patients on long-term metformin to detect macrocytic anaemia followed by biochemical analysis periodically.

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Assessment of health-related quality of life among adult patients with type 2 diabetes mellitus

Abstract: SummaryIntroduction.The aim of the study was to find out the determinants of the quality of life in primary health care patients with type 2 diabetes.

Cited by 3 publications

References 20 publications

The Health-Related Quality of Life of Patients with Type 2 Diabetes in Saudi Arabia

The Health-Related Quality of Life of Patients with Type 2 Diabetes in Saudi Arabia

Assessment of Vitamin B12 Deficiency Caused by Metformin in Type II Diabetic Patients

Assessment of Metformin Induced Vitamin-B12 Deficiency amongst Type-II Diabetic Patients Vis-À-Vis Evaluating the Quality of Life

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