Assessment of health-related quality of life of patients with inflammatory bowel diseases in Eastern Province, Saudi Arabia

Abstract

Inflammatory bowel disease patients have impaired quality of life with physical, social and emotional dysfunction. This project aimed to assess the effects of socio-demographic and clinical variables on quality of life and to identify its predictors. In a cross-sectional paper-based study, 50 consecutive non-selected patients attending the teaching hospital completed a disease-specific McMaster quality of life tool. Socio-demographic and clinical data were collected from patients' records. The t-test and Mann-Whitney test were used to determine the probability of significant differences between quality of life domains and independent variables. Multiple linear regression was used to determine quality of life predictors. Younger and highly educated patients had higher social scores. Those with shorter disease durations had higher systemic scores. Patients in remission had higher systemic, social, bowel and overall scores. Relapse was a significant predictor of decreased systemic, social, bowel and overall scores. Long disease duration was a significant predictor of decreased systemic and overall scores. Younger age at disease onset was a significant predictor of decreased emotional score. However, high education was a significant predictor of improved social score. Relapse, long disease duration, low education and young age at disease onset were associated with low quality of life. Prospective studies should investigate how interventions addressing these predictors may lead to improved quality of life.

Health Related Quality of Life in Patients with Crohn's Disease: A case control Study

“…Poor HRQOL among CD patients has been reported by many studies, but limited studies have examined HRQoL in participants with CD in Saudi Arabia (7,9). The objective of the current study was to compare HRQoL between participants with CD and healthy control individuals and assess the factors that may impact HRQoL in the CD group.…”

“…Additional information was collected from the CD group: age at diagnosis; symptoms related to the disease, including gastrointestinal symptomology (bloody diarrhea, abdominal pain, cramps) and other symptoms reported in different studies (fever, fatigue, mouth ulcer, infection/inflammation in eyes, joint or skin); and drug treatment (7,9).…”

“…There are many factors influencing HRQoL in patients with CD, such as disease symptoms (fatigue), disease activity, number of relapses, and poor sleep quality (2,6). One study examined and compared HRQoL in 31 patients with CD and 19 patients with ulcerative colitis using a disease-specific HRQoL tool in the eastern province of Saudi Arabia (7). The study found that disease activity, disease duration and education level were variables associated with poor HRQoL in patients with CD (7).…”

“…One study examined and compared HRQoL in 31 patients with CD and 19 patients with ulcerative colitis using a disease-specific HRQoL tool in the eastern province of Saudi Arabia (7). The study found that disease activity, disease duration and education level were variables associated with poor HRQoL in patients with CD (7). In addition to the physical factors that may contribute to poor HRQoL in patients with CD, mental and emotional factors such as depression and anxiety have been negatively associated with HRQoL in patients with CD.…”

“…However, limited studies have examined HRQoL in adult patients with CD in Saudi Arabia (7,9). Studies have reported poor HRQoL in patients with CD, but these studies had several limitations, such as small sample size and/or no control group (7,9). The objective of the current study was to assess HRQoL in patients diagnosed with CD in Saudi Arabia, compare…”