Assessment of Hematological Parameters in Malaria, among Adult Patients Attending the Bamenda Regional Hospital

Abstract

Malaria, which is responsible for a substantial amount of deaths in endemic countries, has been shown to have both direct and indirect effects on the hematological parameters. Notwithstanding, some hematological parameters among populations living in malaria endemic regions have not been described consistently, as a standard for measuring malaria burden. Based on the above fact, this study was designed to assess some hematological changes and their diagnostic values in malaria infected patients. A total of 160 malaria positive adult patients, together with 81 healthy control adults were recruited for the study. For the malaria positive group, the female to male ratio was 1.38 : 1. Specifically, 74.38%, 10.00%, and 15.62% of those in the malaria positive group had mild, moderate, and severe parasitaemia, respectively. Leukemia, anemia, and thrombocytopenia were found to be significantly associated with malaria and were all estimated to be specific for the diagnosis of malaria. Anemia was, however, estimated to be both sensitive and specific for malaria diagnosis. Therefore, anemia offers the most diagnostic value in the malaria infected patients of this study.

Haematological Derrangement Due to <i>P. falciparum</i> Infection in Patients of Selected Health Centres in Ardo-Kola Local Government Area, Taraba State

“…Haematological parameters as an investigating tool for cases of early malaria infection may help to detect early complications associated with serious malaria infections so as to help in the cure for the patients and prevent death that may result from such complications. The hematological parameters changes in malaria infected blood sample have been reported [12,13]. The study also revealed that the infected patients tend to have significantly lower platelet, PCV and high FSR, which is in agreement with the present study where platelet counts and PCV where significantly lower in infected than the non-infected subjects.…”

Evaluation of malaria preventive measures among adult patients attending the Bamendjou and Foumbot district hospitals of the West Region of Cameroon

“…Therefore, in addition to females constituting the majority of the study participants, they were also more infected. In line with findings from other studies, higher malaria prevalence among females can be associated with exposure patterns, influenced by socio-economic roles [ 32 , 33 ]. An earlier study suggested that poverty-related issues affected female adoption of malaria control methods [ 34 ].…”

Elevation of free triiodothyronine (fT3) levels by Plasmodium falciparum independent of thyroid stimulating hormone (TSH) in children with uncomplicated malaria

“…parameters 30,[37][38][39] as has been widely published. The mean temperature reading of the malaria patients was 38.78 ± 1.39°C with a significant reduction in erythrocytes, hemoglobin, hematocrit, platelet levels, mean platelet volume, and plateletcrit.…”