Assessment of intellectual functioning of patients with parkinson's disease using the satz-mogel (1962) short form of the wechsler adult intelligence scale

Abstract

The purpose of the present study was to compare the Satz-Mogel (S-M) short form of the Wechsler Adult Intelligence Scale--Revised (WAIS-R) with the full-scale WAIS-R to establish its utility in the assessment of intellectual functioning in patients with Parkinson's disease (PD). PD patients and elderly control subjects were administered a neuropsychological test battery that included the complete WAIS-R or the S-M. Results indicated that the S-M was a reliable measure of IQ. The PD subjects' Verbal, Performance, and Full-Scale IQ scores were inferior to that of controls, regardless of test form. Adjustments for depression and age did not alter these results. PD patients with more severe disease scored lower on some visual-spatial measures. Verbal decrements among PD patients may relate to problems in verbal fluency, categorical thinking, and impaired retrieval of verbal material. PD patients may experience patterns of subtle cognitive changes that include deterioration of some specific abilities as the disease progresses.

Genetic and Environmental Mediation of the Associations Between Self-rated Health and Cognitive Abilities

“…It may also be that particular CNS problems have some direct impact on both health and cognition. Parkinson’s patients may experience subtle cognitive changes that are related to verbal fluency and impaired retrieval of verbal material (Albrecht et al, 1994). Attention and verbal abilities have also shown to be affected among patients with multiple sclerosis (Achiron & Barak, 2003).…”

“…In addition, hypertension and Type 2 diabetes mellitus combined were also associated with detectable cognitive decrements in persons less than 60 years of age (Knopman et al, 2001; Pavlik, Hyman, & Doody, 2005). Neurological problems such as Parkinson’s disease and multiple sclerosis have shown to be related to decrements in cognition (Achiron & Barak, 2003; Albrecht et al, 1994). It has also been reported that cancer- or rather cancer treatment- is related to decrements in cognitive functioning (Ahles & Saykin, 2001).…”

Whole-Brain Voxel-Based Correlation Analysis between Regional Cerebral Blood Flow and Intelligence Quotient Score in Parkinson’s Disease

“…In patients with Parkinson’s disease (PD), general intelligence, as estimated by the intelligence quotient (IQ) score of the Revised Wechsler Adult Intelligence Scale (WAIS-R), declines with disease progression [1, 2]. Neuropathologically, depletion of multiple neuronal networks [3]or cortical changes such as Lewy bodies [4]or Alzheimer-type lesions [5]may account for the decline in IQ, although the specific causal mechanism remains controversial [6].…”