everal studies have reported that evaluation of graft patency by transthoracic Doppler echocardiography (TTDE) is useful in patients who undergo left internal thoracic artery (ITA) to left anterior descending coronary artery (LAD) bypass, 1-5 but as those reports did not include patients with ITA proximal stenosis, little is known about the Doppler flow profile in such grafts. We performed surgical repair of a left ITA (LITA) graft proximal stenosis after coronary artery bypass grafting (CABG) and report the changes in the Doppler flow profile of the graft after repair of proximal stenosis using intraoperative ultrasonography.
Case ReportA 54-year-old male patient underwent elective CABG in June 2000, in which the LITA was anastomosed to the LAD segments 7 and 8 sequentially, the free right ITA to the distal circumflex and first diagonal branch of the left coronary artery sequentially, and the right gastroepiploic artery to segment 4PD of the right coronary artery. The follow-up coronary angiography in January 2001 revealed no ostial stenosis of the LITA graft. Soon after, the patient developed effort angina, so coronary angiography was repeated in July 2001 and a 90% ostial stenosis of the LITA was detected. He underwent surgical intervention, including stent implantation to this lesion 5 times. For a while the symptoms were relieved, but recurrent effort angina developed. The latest coronary angiography examination revealed 90%Circulation Journal Vol. 69, February 2005 stenosis in the stent implanted to the ITA with total occlusion in the proximal LAD ( Fig 1A). It also showed good run-off in the distal LAD. Scintigraphy showed reversible ischemia in the anteroseptal region. Surgical repair of the LITA proximal stenosis was recommended and the patient underwent elective surgery. The left radial artery was taken down in a skeletonized fashion. An arterial catheter was inserted in the femoral artery for continuous coronary artery perfusion. Left lateral thoracotomy was performed because median sternotomy was thought to have a risk of injuring the LITA graft, which was the main vessel perfusing the LAD region. An ultrasonographic probe was attached to the ITA directly and Doppler signals of ITA flow were recorded (Fig 2A). The measurement site was in the middle portion of the ITA graft. Intraoperative ultrasonography was performed with a 7.5 MHz linear array transducer that had been sterilized and connected to an Aloka SSD 5500 Prosound ultrasound system. We placed sterilized jelly between the ITA graft and the transducer for clear visualization. The graft flow pattern obtained consisted of 2 phases of flow corresponding to systole and diastole, as reported previously 1-5 and shown in Table 1. All parameters of ITA flow showed an increase by 2-fold or more compared with before repair, except for peak diastolic-to-systolic velocity ratio, mean diastolic-to-systolic velocity ratio and diastolic fraction, which were almost the same as before repair.After dissecting out the LITA for the anastomosis, it was cut dow...