Assessment of intracranial translucency (IT) in the detection of spina bifida at the 11–13‐week scan

Chaoui, Rabih; Benoit, B.; Mitkowska-Woźniak, Hanna; Heling, K. S.; Nicolaides, Kypros H.

doi:10.1002/uog.7329

Cited by 280 publications

(343 citation statements)

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“…If the fetal head remains the answer for the early detection of OSB, should we use axial or parasagittal planes for screening? 60,61,63,65,[68][69][70] The first question, probably the most important one, is extremely difficult to answer, due to the conflict between ethical principles and available human and technical resources, especially in developing countries.…”

Section: Discussionmentioning

confidence: 99%

“…At this GA, as said before, the direct diagnosis on the basis of the myelomeningocele remained extremely challenging, due probably to size restrictions. Posterior brain anomalies, usually having subtle changes, can be yet identified in the parasagittal plane, used for the NT thickness measurement: compression of the fourth ventricle, leading to decrease or disappearance of the normal intracranial translucency (IT), [60][61][62] altered ranges of the brain stem, 63 nonvisualization of the cisterna magna 64,65 (changes that give the subjective impression of the caudal displacement of the brainstem), decreased fronto maxillary facial (FMF) angle.…”

Section: Osb Diagnosis At the End Of The Ft Of Pregnancy -The Limits mentioning

confidence: 99%

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First Trimester Anomaly Scan—The Last Redoubt Won: Open Spina Bifida

Novac¹,

Tudorache²,

Gabriel³

et al. 2015

Donald School Journal of Ultrasound in Obstetrics and Gynecology

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Open spina bifida (OSB) is a non-lethal fetal anomaly, yet often leads to severe disability. Most cases of open spina bifida are detected at the second trimester fetal anomaly ultrasound scan. The 11 to 13 weeks of amenorrhea scan evolved over the last 20 years from essentially a dating scan, to a genetic scan, and recently to one which includes, in addition to the genetic markers, a basic checklist for examination of the whole fetal anatomy. The direct visualization of the spine at the first trimester (FT) scan remained difficult, despite the wider use of high-reso lution ultrasound machines and the volumetric approach. Thus, indirect intracranial morphological markers for OSB were proposed to diagnose this neural tube defect.The present review aims to describe the specific anatomical feature of the spine and the posterior brain, both on parasagittal and on axial planes, recently proposed for the early detection of OSB.Specialists involved in the prenatal diagnosis will eventually elaborate in the future a screening protocol for OSB in the FT of pregnancy, using the most valuable and easy to obtain marker, in a single 2D plane.The offer of an early diagnosis of possible severe anomalies, such as OSB, is a tool enhancing the autonomy of the pregnant woman.

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Section: Discussionmentioning

confidence: 99%

Section: Osb Diagnosis At the End Of The Ft Of Pregnancy -The Limits mentioning

confidence: 99%

First Trimester Anomaly Scan—The Last Redoubt Won: Open Spina Bifida

Novac¹,

Tudorache²,

Gabriel³

et al. 2015

Donald School Journal of Ultrasound in Obstetrics and Gynecology

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show abstract

“…The main method of screening of open spina bifida was by maternal serum alpha-fetoprotein at around 16th gestational weeks in the 1980s [5] . Spinal defects may be detected directly on ultrasonography (US), however it is hard to visualize spine defects in second trimester.…”

Section: Introductionmentioning

confidence: 99%

Intracranial translucency as a sonographic marker of open spina bifida at first trimester

Kara¹

2014

IJDI

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Spina bifida is the one of the most common severe congenital abnormality of the central nervous system. Scalloping of the frontal bones called "the lemon sign" and caudal displacement of the cerebellum called "the banana sign" are known as cranial signs of open spina bifida on ultrasonography at the second trimester. Although these signs are useful methods in diagnosing of open spina bifida in the second trimester, detection rates of open spina bifida by using these signs in the first trimester are low. Intracranial translucency is a new sonographic landmark that may be valuable for the early detection of open spina bifida in the first trimester.In this study using of intracranial translucency as a sonographic marker of open spina bifida at first trimester is discussed with the light of recent literature.

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“…Thanks to Prof R. Choui for the introduction and correlation of the fourth ventricle in the 11-13 ? 6 weeks scan as the intracranial translucency [2]. The chapter on the anatomy in the 11-13 ?…”

mentioning

confidence: 99%