with cutting efficiency using both flakes and handaxes over extended periods of use and in multiple types of cutting task. Results indicate that (1) both handaxe and flake cutting efficiency is significantly related with biometric variation of individual tool-users, (2) relationships between biometric parameters and efficiency are consistent across extended durations but vary dependent upon task-type conditions, (3) manipulative strength is the most significant biometric trait in terms of predicting flake efficiency, while (4) hand size is the strongest predictor of handaxe cutting efficiency. These results demonstrate the long-term impact that stone tool use likely had on the evolution of hominin biometric variation during the Lower Palaeolithic, while also highlighting the variable influence of different tool use contexts.Most notably, results indicate that the onset of the Acheulean may have been dependent, a priori, upon hand dimensions that are close to the modern human range, and that prior to the appearance of this anatomy, handaxe use would have been an impractical (i.e. inefficient) tool use behaviour compared to the use of flakes.