Wastes are generated as a result of anthropogenic activities. The rapid industrialization of human society in the twenty-first century has led to an increase in the generation of industrial wastes that have negatively impacted humans and the environment. While industrial operations and techniques have improved globally, leading to a higher standard of living, economic prosperity, and healthcare delivery, industries have continued to produce waste on a scale never before seen. This chapter discussed industrial wastes, waste generation, and industries involved, waste disposal, landfilling as a disposal method, effects of waste disposal, modern techniques in industrial waste management, landfill sustainability, and regulations.