Assessment of left ventricular ejection fraction after myocardial infarction using contrast echocardiography

Galema, Tjebbe W.; Geleijnse, Marcel L.; Yap, Sing-Chien; Domburg, Ron T. van; Biagini, Elena; Vletter, Wim B.; Cate, Folkert J. ten

doi:10.1016/j.euje.2007.03.025

Cited by 20 publications

(18 citation statements)

References 22 publications

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“…Moreover, it is comparable to the variability of e LL that has previously been reported for 3D deformation imaging by block matching [15]. Nevertheless even the intra-observer variability of such a widely recognized parameter as LV ejection fraction exceeds 10%, when no contrast enhancement is used [21,22].…”

Section: Discussionsupporting

confidence: 62%

Comparison of a new methodology for the assessment of 3D myocardial strain from volumetric ultrasound with 2D speckle tracking

Jasaitytė

Heyde

Ferferieva

et al. 2011

Int J Cardiovasc Imaging

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An alternative approach to extract 3D myocardial strain based on elastic registration of the ultrasound images (3DSE) was developed by our lab. The aim of the present study was to test its clinical performance by comparing strain values obtained by 3DSE with the ones obtained with 2D speckle tracking (2DST). Standard 2D B-mode and volumetric datasets were acquired in 12 patients with coronary heart disease (CHD) and in 12 control subjects. Longitudinal (ε(LL)), circumferential (ε(CC)) and radial (ε(RR)) strain values were obtained from 2D datasets using commercially available 2DST software and from volumetric datasets using the 3DSE approach. 3DSE provided lower strain values than 2DST. With both approaches global ε(LL) and ε(CC) were significantly lower in patients with CHD than in controls. Global ε(LL) and ε(CC) correlated well between both methods (R = 0.83, R = 0.86, respectively), while segmental correlations were moderate [R = 0.63 (ε(LL)), R = 0.41 (ε(CC))]. The highest differences in ε(LL) values obtained by the two methods and the highest number of erroneous ε(LL) with 3DSE were observed in the basal LV segments. This study shows that in real-life datasets our 3DSE method provides global and regional ε(LL) and ε(CC) values that are comparable with the ones obtained from 2DST, even though they are not interchangeable with each other. As only a single acquisition is required, 3D methods may offer advantages over the current 2D techniques. However, the accuracy of the 3DSE can still be improved by solving the problems that appear with deformation estimation in the basal segments.

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Section: Discussionsupporting

confidence: 62%

Comparison of a new methodology for the assessment of 3D myocardial strain from volumetric ultrasound with 2D speckle tracking

Jasaitytė

Heyde

Ferferieva

et al. 2011

Int J Cardiovasc Imaging

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“…Cine loops of 2–4 cardiac cycles from the parasternal short axis (papillary muscle level) and apical four chamber views were digitized at a high rate and stored offline in DICOM format. Each study was assessed for image quality by an experienced operator, blinded to all other clinical and echocardiographic data, using a 4-point scale based on the degree of endocardial border visualized (1 = 0–25%; 2 = 25%–50%; 3 = 50%–75%; 4 = 75%–100%), similar to scales used previously (21,22). …”

Section: Methodsmentioning

confidence: 99%

Association of Estimated Sodium Intake With Adverse Cardiac Structure and Function

Selvaraj

Djoussé

Aguilar

et al. 2017

Journal of the American College of Cardiology

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Background The optimal level of sodium intake remains controversial. Objective To determine whether examination of left ventricular (LV) longitudinal and circumferential strain (LS, CS) and e′ velocity can provide insight into thresholds for the detrimental effects of estimated sodium intake (ESI) on subclinical cardiovascular disease. Methods We performed speckle-tracking analysis on Hypertension Genetic Epidemiology study echocardiograms with available urinary sodium data (N = 2,996). We evaluated the association between ESI and LS, CS, and e′ velocity using multivariable-adjusted linear mixed effects models (to account for relatedness among subjects) with linear splines (spline 1: ESI ≤3.7g/day, spline 2: ESI >3.7g/day based upon visual inspection of fractional polynomial plots of the association between ESI and indices of strain and e′ velocity). We performed mediation analysis to understand the indirect effects of systolic blood pressure (SBP) and serum aldosterone on the relationship between ESI and strain and e′ velocity. Results Mean age was 49 ± 14 years, 57% were female, 50% were African American, and 54% had hypertension. The median (25th–75th percentile) ESI was 3.73 (3.24–4.25) g/day. ESI >3.7g/day was associated with larger left atrial and LV dimensions (p <0.05). After adjusting for speckle-tracking analyst, image quality, study site, age, sex, smoking status, alcohol use, daily blocks walked, diuretic use, estimated glomerular filtration rate, LV mass, ejection fraction, and wall motion score index, ESI >3.7g/day was associated with all strain parameters and e′ velocity in (p <0.05 for all comparisons), but ESI ≤3.7g/day was not (p >0.05 for all comparisons). There were significant interactions by potassium excretion for CS. Mediation analysis suggested that SBP explained 14% and 20% of the indirect effects between ESI and LS and e′ velocity, respectively, while serum aldosterone explained 19% of the indirect effects between ESI and LS. Conclusions ESI >3.7 g/day is associated with adverse cardiac remodeling and worse systolic strain and diastolic e′ velocity.

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“…Each study was assessed for image quality by an experienced operator, blinded to all other clinical and echocardiographic data, using a 4-point scale based on the degree of endocardial border visualized (1 = 0-25%; 2 = 25%-50%; 3 = 50%-75%; 4 = 75%-100%), similar to scales used previously. 17, 18 …”

Section: Methodsmentioning

confidence: 99%

Association of Central Adiposity With Adverse Cardiac Mechanics

Selvaraj

Martinez

Aguilar

et al. 2016

Circ: Cardiovascular Imaging

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Background Central obesity, defined by increased waist circumference (WC) or waist-hip ratio (WHR), is associated with increased cardiovascular (CV) events, including heart failure. However, the pathophysiological link between central obesity and adverse CV outcomes remains poorly understood. We hypothesized that central obesity and larger WHR are independently associated with worse cardiac mechanics (reduced left ventricular [LV] strain and systolic [s’] and early diastolic [e’] tissue velocities). Methods and Results We performed speckle-tracking analysis of echocardiograms from participants in the HyperGEN study, a population- and family-based epidemiologic study (N=2181). Multiple indices of systolic and diastolic cardiac mechanics were measured. We evaluated the association between central obesity and cardiac mechanics using multivariable-adjusted linear mixed effects models to account for relatedness among participants. The mean age of the cohort was 51±14 years, 58% were female, and 47% were African-American. Mean body-mass index (BMI) was 30.8±7.1 kg/m2, WC 102±17 cm, WHR 0.91±0.08, and 80% had central obesity based on WC and WHR criteria. After adjusting for multiple potential confounders, including age, sex, race, physical activity, BMI, heart rate, smoking status, systolic blood pressure, fasting glucose, total cholesterol, anti-hypertensive medication use, glomerular filtration rate, LV mass index, wall motion abnormalities, and ejection fraction, central obesity and WHR remained associated with worse global longitudinal strain, early diastolic strain rate, s’ velocity, and e’ velocity (P < 0.05 for all comparisons). There were no significant statistical interactions between WHR and obesity status. Conclusions In this cross-sectional study of participants with multiple comorbidities, central obesity was found to be associated with adverse cardiac mechanics.

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Assessment of left ventricular ejection fraction after myocardial infarction using contrast echocardiography

Cited by 20 publications

References 22 publications

Comparison of a new methodology for the assessment of 3D myocardial strain from volumetric ultrasound with 2D speckle tracking

Comparison of a new methodology for the assessment of 3D myocardial strain from volumetric ultrasound with 2D speckle tracking

Association of Estimated Sodium Intake With Adverse Cardiac Structure and Function

Association of Central Adiposity With Adverse Cardiac Mechanics

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