Assessment of left ventricular function in chronic alcoholics by real-time three-dimensional echocardiography

Wang, Yuanzheng; Shan, Guoxin; Shen, Jiemin; Zhou, Qiao; Tan, Bijun; Liu, Yue; Luo, Runlan; Zhao, Shifen; Wen-jun, BI; Yao, Fangyi; Li, Guangsen

doi:10.1097/md.0000000000006033

Cited by 6 publications

(8 citation statements)

References 54 publications

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“…We obtained a C-SDI of 8.0 ± 3.4% in the control group, higher than previously published ranges, [25] though differences in design and methodology as well as the sample size, could explain the differences. We cannot compare our findings in CA with other reports, but equivalent results have been shown in alcohol induced cardiomyopathy with realtime 3D echocardiography, with increased SDI in addicts compared to controls [49].…”

Section: Dyssynchrony Indexcontrasting

confidence: 58%

Detection of subclinical myocardial dysfunction in cocaine addicts with feature tracking cardiovascular magnetic resonance

Maceira

Guardiola²,

Ripoll

et al. 2020

Journal of Cardiovascular Magnetic Resonance

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Background Cocaine is an addictive, sympathomimetic drug with potentially lethal effects. We have previously shown with cardiovascular magnetic resonance (CMR) the presence of cardiovascular involvement in a significant percentage of consecutive asymptomatic cocaine addicts. CMR with feature-tracking analysis (CMR-FT) allows for the quantification of myocardial deformation which may detect preclinical involvement. Therefore, we aimed to assess the effects of cocaine on the left ventricular myocardium in a group of asymptomatic cocaine users with CMR-FT. Methods In a cohort of asymptomatic cocaine addicts (CA) who had been submitted to CMR at 3 T, we used CMR-FT to measure strain, strain rate and dyssynchrony index in CA with mildly decreased left ventricular ejection fraction (CA-LVEFd) and in CA with preserved ejection fraction (CA-LVEFp). We also measured these parameters in 30 age-matched healthy subjects. Results There were no differences according to age. Significant differences were seen in global longitudinal, radial and circumferential strain, in global longitudinal and radial strain rate and in radial and circumferential dyssynchrony index among the groups, with the lowest values in CA-LVEFd and intermediate values in CA-LVEFp. Longitudinal, radial and circumferential strain values were significantly lower in CA-LVEFp with respect to controls. Conclusions CA-LVEFp show decreased systolic strain and strain rate values, with intermediate values between healthy controls and CA-LVEFd. Signs suggestive of dyssynchrony were also detected. In CA, CMR-FT based strain analysis can detect early subclinical myocardial involvement.

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Section: Dyssynchrony Indexcontrasting

confidence: 58%

Detection of subclinical myocardial dysfunction in cocaine addicts with feature tracking cardiovascular magnetic resonance

Maceira

Guardiola²,

Ripoll

et al. 2020

Journal of Cardiovascular Magnetic Resonance

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“…Some epidemiological studies have shown beneficial effect of low alcohol consumption [6][7][8][9][10][11][12][13]. Although low alcohol consumption has some beneficial effects, the number of investigations of side effects of alcohol consumption commonly increase, as in our study [6][7][8][9][10][11][12][13]. Alcoholic cardiomyopathy (CMP) is defined as enlarged cardiac chambers with largely hypertrophy and extracellular matrix (ECM) remodeling [1].…”

Section: Discussionmentioning

confidence: 98%

“…Except for LA dimensions, these findings are consistent with our observations regarding the left ventricular ejection fraction. Therefore, diastolic dysfunction associated with alcohol use carries clinical significance as an initial sign of the CMP process [1,9,17,20]. It should also be borne in mind that other factors may have a predictive role in the development of alcoholic cardiac disease and these include the duration, frequency, and amount of alcohol consumption, the type of alcohol consumed, presence of additional substance abuse (cigarette, marihuana), and family history of cardiomyopathy [3,4,12,13].…”

Section: Discussionmentioning

confidence: 99%

“…In these individuals, the mechanisms of alcohol toxicity and potential cardio-protective effects continue to be investigated due to different outcomes in various studies [5,6,7]. Chronic heavy alcohol drinking may lead to cardiovascular, metabolic, and toxic disorders, abnormalities in ventricular diastolic and/or systolic dysfunction, elevated arterial blood pressure, angina pectoris, coronary artery disease, arrhythmia, and even sudden cardiac death, increased risk of stroke, obesity, cancer, liver diseases, etc [6][7][8][9][10][11][12][13]. Therefore, early detection of the sub-clinical cardiac abnormalities is essential to chronic heavy alcohol drinkers which can be detected with electrocardiographic and echocardiographic evaluation and, benefit from early treatment.…”

Section: Introductionmentioning

confidence: 99%

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Chronic heavy alcohol consumption and asymptomatic cardiovascular effects: An observational study

2020

Ann Clin Anal Med

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Aim: The association between chronic heavy alcohol consumption and a number of adverse cardiovascular consequences such as hypertension, dyslipidemia, dysrhythmia, coronary artery disease, sudden cardiac death, and particularly dilated cardiomyopathy is becoming increasingly more evident. In this study, our objective was to determine the preclinical cardiac effects of chronic heavy alcohol consumption in young and middle-aged asymptomatic healthy individuals. Material and Methods: The study is planned as cross-sectional and observational. A total of 40 men between 25 and 55 years of age with weekly alcohol consumption of ≥ 850 g for a minimum duration of 8 years (chronic heavy alcohol group) and 40 men with no alcohol use (control group) were included. The demographic characteristics, results of echocardiographic and electrocardiographic assessments and epicardial adipose tissue thickness were recorded. Results: Individuals with alcohol use had significantly higher systolic and diastolic blood pressures, increased left atrial antero-posterior diameter, increased interventricular septum and posterior wall thickness, and higher incidence of stage 1 diastolic dysfunction (p< 0.05). Epicardial adipose tissue thickness was higher in alcohol users group compared to the control group (5.46±1.65 vs 3.20±1.03, p = 0.0001). Also, the incidence of atrial fibrillation and right bundle branch block were increased compared to the control group. Discussion: Our results have shown that chronic heavy alcohol consumption is associated with diastolic dysfunction, increased epicardial adipose tissue thickness, electrocardiographic disturbances, and atrial fibrillation. These findings show that alcohol use leads to a variety of asymptomatic changes in cardiac functions.

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“…68%) followed by alcohol consumption between 5 to 8 years of age group (i.e. 32%) (Wang et al, 2017).…”

Section: Literature Reviewmentioning

confidence: 99%

Assessment of Cardiac Functions in Chronic Alcoholics

Toshniwal

Patil

2020

ijrps

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The present observational study was conducted to evaluate the cardiological manifestations in chronic alcoholic in relation with Electrocardiographic and 2-Dimensional Transthoracic Echocardiogram and Doppler findings. In Present study we observed most common 2-D echocardiographic finding being Grade 1 Diastolic Dysfunction (i.e. 28.35%), followed by Left ventricular Dysfunction (i.e.7.87%) being second most common finding, followed by mild Pulmonary Hypertension (i.e. 5.51%). In present study, the observed most common Electrocardiographic finding being sinus rhythm ( i.e. 34.6%) followed by second most common finding being atrial fibrillation (i.e. 13.38%) followed by sinus tachycardia ( i.e. 11.18%) so most common abnormal elctro-cardiographic finding is Atrial fibrillation. The present study was crosssectional, descriptive, hospital based observational study to assess cardiac function in chronic alcoholic by use of Electrocardiogram and Two Dimensional Transthoracic Echocardiogram and Doppler function. Duration of Study is 18 months and Study Setting is conducted in patients admitted in wards and ICU under Department of Medicine, Krishna Hospital and Medical Research Centre, Karad. There is Study Population is all alcoholic patients admitted in wards and ICU during the period from October 2016 to March 2018 under Department of Medicine, Krishna Hospital and Medical Research Centre Karad with alcohol consumption duration more than 5 years.

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Assessment of left ventricular function in chronic alcoholics by real-time three-dimensional echocardiography

Cited by 6 publications

References 54 publications

Detection of subclinical myocardial dysfunction in cocaine addicts with feature tracking cardiovascular magnetic resonance

Detection of subclinical myocardial dysfunction in cocaine addicts with feature tracking cardiovascular magnetic resonance

Chronic heavy alcohol consumption and asymptomatic cardiovascular effects: An observational study

Assessment of Cardiac Functions in Chronic Alcoholics

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