2021
DOI: 10.3748/wjg.v27.i23.3223
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Assessment of liver disease in patients with chronic hepatitis C and unhealthy alcohol use

Abstract: Hepatitis C virus (HCV) infection and unhealthy alcohol use are major drivers of the burden of liver disease worldwide and commonly co-occur. Assessment of underlying liver damage is a cornerstone of the clinical care of patients with chronic HCV infection and/or unhealthy alcohol use because many of them are diagnosed at advanced stages of disease. Early diagnosis of liver disease before decompensated liver cirrhosis becomes established is essential for treatment with direct acting antivirals and/or abstinenc… Show more

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Cited by 3 publications
(3 citation statements)
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“…Combined use of ultrasound and elastography, commonly referred to as sonoelastography, has successfully been used as a diagnostic tool in various pathologies, such as breast tumors, chronic liver disease, lung lesions or prostate cancer [ 16 , 17 , 18 , 19 ]. Application of TVUS combined with elastography in gynecology has been highlighted by studies, proving its efficacy in diagnosing and differentiating cervical, uterine wall and endometrial lesions [ 20 , 21 , 22 ].…”
Section: Discussionmentioning
confidence: 99%
“…Combined use of ultrasound and elastography, commonly referred to as sonoelastography, has successfully been used as a diagnostic tool in various pathologies, such as breast tumors, chronic liver disease, lung lesions or prostate cancer [ 16 , 17 , 18 , 19 ]. Application of TVUS combined with elastography in gynecology has been highlighted by studies, proving its efficacy in diagnosing and differentiating cervical, uterine wall and endometrial lesions [ 20 , 21 , 22 ].…”
Section: Discussionmentioning
confidence: 99%
“…This non-invasive elastography test is currently the most reliable noninvasive method for the diagnosis of advanced liver fibrosis and cirrhosis in ALD [ 25 ]. In a prospective, direct comparison of tests, Enhanced Liver Fibrosis test (ELF) and Fibroscan ® identified advanced liver fibrosis in alcoholic patients from primary and secondary care with high diagnostic accuracy (AUROC values of 0.90 or higher using biopsy as reference) [ 26 ] and several studies have used transient elastography in patients with ALD [ 25 , 27 31 ].…”
Section: Alcohol-related Liver Diseasementioning
confidence: 99%
“…This non-invasive elastography test is currently the most reliable noninvasive method for the diagnosis of advanced liver fibrosis and cirrhosis in ALD [25]. In a prospective, direct comparison of tests, Enhanced Liver Fibrosis test (ELF) and Fibroscan ® identified advanced liver fibrosis in alcoholic patients from primary and secondary care with high diagnostic accuracy (AUROC values of 0.90 or higher using biopsy as reference) [26] and several studies have used transient elastography in patients with ALD [25,[27][28][29][30][31].…”
Section: Supplementary Testsmentioning
confidence: 99%