Assessment of medication therapy adherence in glaucoma: scoping review

Rosu, Amalia Mihaela; Coelho, André; Camacho, Pedro

doi:10.1080/17469899.2020.1842197

Cited by 1 publication

(2 citation statements)

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“…In fact, almost one out of five patients under 45y interrupted their glaucoma treatment after the first dispensing. Similar results for other components of medication adherence were found by Rosu et al [13] . Different factors may play a role in this decision: as we already mentioned, it's well known that the asymptomatic nature of glaucoma reduces patient motivation to take the drugs as prescribed, which might be more relevant for younger patients.…”

Section: Discussionsupporting

confidence: 90%

“…The process starts with initiation of the treatment, which occurs when the patient takes the first dose of a prescribed medication, after its acquisition from a pharmacy and it ends (discontinuation) when the patient stops taking the prescribed medication [12] . Typically, the literature on medication adherence focuses on the implementation of therapy, skipping its first element, initiation [13] . Also, many patients interrupt their treatment after the acquisition in a pharmacy of their first prescription, phenomena called early discontinuation or short persistence [14] .…”

Section: Introductionmentioning

confidence: 99%

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Initial medication adherence in newly diagnosed glaucoma patients: three adherence measures

Menino¹,

Coelho²

2023

Int J Ophthalmol

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AIM: To determine initial medication adherence in newly diagnosed glaucoma patients treated with anti-glaucoma drugs. METHODS: This retrospective and observational study included all patients diagnosed with glaucoma in the Primary Health Care units in Portugal during the years 2012 and 2013, which in consequence received a first prescription for anti-glaucoma drugs. Data was collected from electronic prescribing records of the primary care units and from pharmacy claims records. Initiation of glaucoma treatment and early discontinuation were measured, and the combination of (non)-initiation and early discontinuation accounted for initial medication (non)-adherence. RESULTS: A total of 3548 new glaucoma patients (40.1% male; 59.9% female) were included. The 1133 (31.9%) patients were initially classified as non-users, since there was no pharmacy claim found for their first prescription for glaucoma treatment. Additionally, 277 (11.5%) patients early discontinued their treatment, acquiring only their first prescription. Overall, the initial medication non-adherence rate was 39.7% since 1410 patients either didn’t initiate treatment or discontinued it early. CONCLUSION: This study, reveals a major opportunity to improve glaucoma treatment and its control, since a large proportion of patients fail to engage with their prescribed therapy, which implies that implementation of individual or group strategies that enable patients with glaucoma to correctly perform their treatment is still needed.

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Section: Discussionsupporting

confidence: 90%