Assessment of Microneedling Devices as Transepidermal Drug Delivering System for Corticosteroid in Treatment of Hypertrophic Scars

Abstract

Background: Hypertrophic scars are one of dermal fibroproliferative disorders which can lead to pruritus, disfigurement and pain. The use of microneedling to introduce topical agents or drugs into the dermis is a rapidly growing and popular skin/scar treatment.Patients and Methods: This is a prospective randomized study that included 30 patients suffering from Hypertrophic scars and they are candidate for the proposed technique. Microneedling by Dermapen device with application of topical triamcinolone acetonide solution on scar tissue for three sessions with 3 weeks interval in between.Results: During one year, 30 patients were recruited in our study, the mean age of the patients was 28.16±11.24 (range 21-58 year) and 52% of patients were female. Lesions location were anterior chest (8), extremities (18) and back (4). Mean zero VSS scores were achieved with triamcinolone transepidermal injection in respect of scar height (week 15 th ) and pliability (week 15 th ). Conclusion:Our results did support the capability of triamcinolone transepidermal injection using Dermapen in treatment of hypertrophic scars, with an efficient, less painful and cost-effective procedure.