Assessment of mitral regurgitation

Irvine, Timothy; Li, X. K.; Sahn, David J.; Kenny, Antoinette

doi:10.1136/heart.88.suppl_4.iv11

Cited by 37 publications

(47 citation statements)

References 45 publications

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“…Among CV risk factors, hypertension and type II diabetes were present in 26 and 21% of the patients; respectively. Chronic kidney disease, classified according to the National Kidney Foundation [7], was found in 35% of the patients.…”

Section: Resultsmentioning

confidence: 99%

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NT-ProBNP and hsTnI: A Multistate Survival Analysis in Outpatients with Reduced Left-Ventricular Ejection Fraction

et al. 2019

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Heart failure (HF) with reduced ejection fraction (HFrEF) has a well-known epidemic relevance in western countries. It affects up to 1–2% of patients > 60 years and reaches a prevalence of 12% in octogenarian patients. The role of N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitive troponin I (hsTnI) in risk stratifying HFrEF patients has been established; at present, evidence is exclusively based on one-time assessments, and the prognostic usefulness of serial biochemical assessments in this population still remains to be determined. We prospectively recruited 226 patients with chronic HFrEF, who were all referred to the Outpatient Clinic of our institution from November 2011 through September 2014. Recruited patients underwent full clinical evaluation with complete history taking and physical examination as well as ECG, biochemical assessment, and standard 2D and Doppler flow echocardiography at the first visit, and then again at each visit during the follow-up, repeated every 6 months. During the follow-up period, cardiovascular (CV) death, which occurred in 16 patients, was not statistically correlated with gender (p = 0.088) or age (p = 0.1636); however, baseline serum levels of NT-proBNP, which were 3 times higher in deceased patients, were significantly related to this clinical event (p = 0.001). We found that NT-proBNP represents a strong and independent predictor of CV outcome; serum levels of hsTnI, which are significantly related to an increased risk of hospitalization, cannot properly predict the relative risk of CV mortality. Our study validates, eventually, the multimarker strategy, which reflects the complexity of the HF pathophysiology.

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Section: Resultsmentioning

confidence: 99%

“…TAPSE was measured as the total displacement of the tricuspid annulus (in cm) from end diastole to end systole. Right-ventricular systolic pressure was calculated by inserting the tricuspid regurgitation velocity, obtained with continuous-wave Doppler, into the simplified Bernoulli equation [6, 7]. …”

Section: Methodsmentioning

confidence: 99%

NT-ProBNP and hsTnI: A Multistate Survival Analysis in Outpatients with Reduced Left-Ventricular Ejection Fraction

et al. 2019

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“…3 A perception on the degree of MR is formed by delineating the anatomical lesions (a flail leaflet is highly suggestive of severe MR), by observing the left atrial penetration and direction of the jet (an eccentric jet is suspicious for severe MR), by noting the size Approach 2: the "vena contracta" is a simple and useful tool The vena contracta is the narrowest neck of the regurgitant flow through and immediately below the regurgitant orifice. 16 The width of the vena contracta seen by colour flow imaging is a surrogate for the regurgitant orifice size.…”

Section: Approach To Quantitation Of Mrmentioning

confidence: 99%

“…In the past decade new methods and new concepts have been developed for the quantitation of MR, which have been detailed by Irvine and colleagues in this supplement to Heart. 3 As one may ponder the incremental benefit of new approaches, it is important to review their rationale, to delineate how to integrate them in a global approach, and how to interpret these new results.…”

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confidence: 99%

Stuck mitral valve replacement

Pemberton¹,

Irvine²,

Kenny³

2002

Heart

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“…Ressalte-se que o emprego de métodos baseados em imagens planares bidimensionais podem ser insuficientes para demonstrar uma localização espacial exata da patologia e das estruturas, e sendo necessária uma reconstrução mental tridimensional anatômica da válvula pelo examinador, tamanho do jato regurgitante e na presunção de sua geométrica dentro do AE (37) .…”

Section: Métodosunclassified

Fibrose miocárdica associada à insuficiência mitral crônica: estudo pela ressonância magnética

Mansano¹

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Assessment of mitral regurgitation

Cited by 37 publications

References 45 publications

NT-ProBNP and hsTnI: A Multistate Survival Analysis in Outpatients with Reduced Left-Ventricular Ejection Fraction

NT-ProBNP and hsTnI: A Multistate Survival Analysis in Outpatients with Reduced Left-Ventricular Ejection Fraction

Stuck mitral valve replacement

Fibrose miocárdica associada à insuficiência mitral crônica: estudo pela ressonância magnética

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