One of the biggest problems of environmental protection in Serbia is landfills. It is often a case that the economic interests are predominant in the landfill sitting; thus, most landfills are not located according to standards. This study shows that detailed geological data assets combined with geographical modeling represents a reliable way to define and locate the landfill site. Geological evaluation is discussed in detail with regard to bedrock lithology, quaternary geology, geological structure, hydrogeology, surface runoff patterns, and topography. An approach combining geographical modeling and geology is presented for determining the sites suitable for landfill selection with respect to their geologic favorability. As opposed to numerous research papers on this topic, in the methodological procedure, special importance is devoted to the analysis of the geological criteria. In this way, it is significantly easier to determine the landfill area with the best characteristics due to geological structure and lithology which unequivocally and precisely indicates inadequate territories for candidate sites. The multicriteria decision analysis (MCDA) is based on geological criteria upgraded with road (primary, residential, secondary, and tertiary), settlements network, railway, airport, infrastructure, land use, hypsometry aquifer, wetland, and surface water. The score values are divided into four classes, i.e., restricted areas, suitable but avoid, suitable, and most suitable. Combining geographical modeling with geology led to the recognition of two locations to be most favorable for landfill site located in the most suitable area, which represents 25.3% of the study area.