Assessment of Neuropathic Pain in Primary Care

Is an easy and reliable diagnosis of localized neuropathic pain (LNP) possible in general practice? Development of a screening tool based on IASP criteria

“…However, evidence-based medications were only documented for 22% of patients with LNP in the present study. General pain treatment usually begins with NSAIDs or paracetamol which can provide relief for the nociceptive component in mixed pain such as low back pain but were found to be largely ineffective in neuropathic pain 32 , and are neither suitable nor safe for long-term chronic pain treatment. An early diagnosis of NP and LNP allows a revision of this initial treatment decision.…”

The association between prescribed opioid use for mothers and children: a record-linkage study

“…This number has been increasing steadily over the years parallel to that of many other developed countries [2][3][4][5][6][7][8][9][10]. Increased efforts to address the assumed under-treatment of pain [11] may be one explanation, as extensive literature has shown that pain management is critical in order to achieve a favorable quality of life and improve medical outcome [12].…”

A Synthetic Cell-Penetrating Peptide Antagonizing TrkA Function Suppresses Neuropathic Pain in Mice

“…Chronic pain is classified into 3 categories: nociceptive pain, neuropathic pain, and pain without a known somatic background (1). Neuropathic pain is a common symptom, defined as pain resulting from lesions or diseases of the sensory transmission pathways in the peripheral or central nervous system (2,3).…”