Assessment of nutritional status in adult patients with cystic fibrosis: Whole-body bioimpedance vs body mass index, skinfolds, and leg-to-leg bioimpedance

Hollander, F.M.; Roos, N.M. de; Vries, J.H.M. de; Berkhout, F. Teding van

doi:10.1016/j.jada.2005.01.030

Cited by 29 publications

(19 citation statements)

References 20 publications

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“…Many patients in this study had nutritional deficit and altered pattern of spirometry, a common situation in adolescents and adults with cystic fibrosis, because the nutritional status, body mass, BMI follow the pulmonary function and indicate a better prognosis (26,27). The use of percentile of BMI in this study is consistent with the literature, because in children over 2 years this indicator is related to adequate growth, besides a lower risk of death (28).…”

Section: Aspectos Clínicos Y Nutricionales De Pacientes Con Fibrosis supporting

confidence: 83%

Clinical and nutritional aspects of cystic fibrosis patients assisted by a home enteral nutrition program in Brazil

Haack¹,

Novaes

2013

Rev. chil. nutr.

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Section: Aspectos Clínicos Y Nutricionales De Pacientes Con Fibrosis supporting

confidence: 83%

Clinical and nutritional aspects of cystic fibrosis patients assisted by a home enteral nutrition program in Brazil

Haack¹,

Novaes

2013

Rev. chil. nutr.

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“…For example, the increase in body fat with age, or changes in composition occurring during weight loss interventions or as a consequence of diseases or drug treatments. [11][12][13][14] This study examines the validity of the leg-to-leg BIA (LTL) device against a multi-compartment model during a period of weight loss and weight regain. Previous studies have shown reasonable agreement in cross-sectional analyses in different populations and situations 10,[13][14][15][16] but it is possible that the change in fatness may be measured with greater accuracy as some of the errors may cancel out.…”

Section: Introductionmentioning

confidence: 99%

Validity of the leg-to-leg bioimpedance to estimate changes in body fat during weight loss and regain in overweight women: a comparison with multi-compartment models

et al. 2006

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Objectives: To investigate changes in body composition and the validity of the leg-to-leg bioimpedance (LTL) method to measure body fat during active weight loss (WL) and weight regain (WR). Design: Longitudinal, 12-week weight loss intervention (3.3-3.8 MJ/day) and subsequent follow-up at 1 year. Subjects: Fifty-eight adult women aged between 24 and 65 years (mean age: 46.878.9 years) and with a body mass index (BMI) X25 kg/m 2 (mean BMI: 31.672.5 kg/m 2 , range ¼ 26.0-48.2 kg/m 2 ) participated in the study. Measurements: Fat mass (FM) was measured at baseline, 12 weeks, 24 weeks and 52 weeks using three-and four-compartment (4-C) models, air displacement plethysmography (ADP), deuterium dilution -total body water (TBW), dual-energy X-ray absorptiometry (DXA), skinfold thickness (SFT), tetrapolar bioelectrical impedance analysis (T-BIA) and LTL. Results: At the end of the weight loss programme, subjects lost 9.973.5 kg weight (Po0.001) and 7.670.5 kg fat (Po0.001) but after 1 year they had regained 4.973.7 kg of weight and 3.772.9 kg of fat. The 4-C model showed that FM and TBW accounted for 76.2 and 23.6% of the loss in body mass and 81.8 and 17.7% of the tissue accrued during weight regain, respectively. The estimate of body fat change by LTL relative to multi-compartment models (WL bias72s.d Conclusions: Weight loss and regain were associated with minimal changes in lean tissue as measured using multicompartment models. The LTL system is a useful method to measure body composition changes during clinical weight management programmes.

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“…Body composition was assessed by bioelectrical impedance (BIA 101 Impedance Analyzer; RJL Systems, Detroit, Mich., USA). Fat-free mass (FFM) was calculated using a specific regression equation [15] and was expressed in kilograms. FM was calculated as total weight minus FFM and expressed in kilograms.…”

Section: Methodsmentioning

confidence: 99%

Association of Nesfatin-1 and Fat Mass in Cystic Fibrosis

et al. 2013

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Background: The mechanisms of fat mass (FM) loss in cystic fibrosis (CF) are poorly understood but could represent complex pathways involving dysregulation of appetite-modulating peptides and an amplified inflammatory response. Nesfatin-1 is a newly described peptide that decreases food intake and FM but has not been studied in CF. Objectives: We hypothesized that changes in the appetite-suppressing hormone nesfatin-1 would be physiological, and levels would be lower in advanced CF patients with lower FM compared to those with milder disease and healthy controls. We determined the levels of the cytokines TNF-α, IL-1β, and IL-6 as they have been associated with weight loss in disease states. Methods: Fifty-four adult CF subjects, i.e. 17 with severe, 22 with moderate, and 15 with mild disease, as well as 18 controls were recruited. PFT and body composition analysis (via bioelectrical impedance) were performed. Nesfatin-1 and cytokine levels were determined by ELISA. Results: Contrary to our proposed hypothesis, nesfatin-1 levels were highest in CF patients with severe disease and the lowest FM. A significant negative correlation between nesfatin-1 levels and FM was found only in the severe CF group (r = -0.7, p = 0.003). In forward stepwise regression analysis, only FM was significantly associated with nesfatin-1 levels. Levels of TNF-α and IL-6 were elevated in the severe CF group, but there was no association with either FM or nesfatin-1. Conclusion: In advanced CF and low FM, nesfatin-1 plasma levels are significantly increased and inversely correlated with the FM. Our results further suggest that nesfatin-1 exerts its effects independently of TNF-α or IL-6.

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Assessment of nutritional status in adult patients with cystic fibrosis: Whole-body bioimpedance vs body mass index, skinfolds, and leg-to-leg bioimpedance

Cited by 29 publications

References 20 publications

Clinical and nutritional aspects of cystic fibrosis patients assisted by a home enteral nutrition program in Brazil

Clinical and nutritional aspects of cystic fibrosis patients assisted by a home enteral nutrition program in Brazil

Validity of the leg-to-leg bioimpedance to estimate changes in body fat during weight loss and regain in overweight women: a comparison with multi-compartment models

Association of Nesfatin-1 and Fat Mass in Cystic Fibrosis

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