SummaryPercutaneous coronary intervention (PCI) of ostial lesions is complex and is technically very demanding. Intravascular ultrasound (IVUS) is considered the gold standard method to guide PCI but has several limitations. Stent boost subtract (SBS) imaging is an enhancement of the radiologic edge of the stent by digital management of regular X-ray images. The purpose of this study was to determine the availability of stent enhancement with SBS during ostial PCI by comparison with IVUS.We investigated SBS and IVUS after stent implantation in 58 ostial lesions in 55 patients. SBS and IVUS were performed in all patients to obtain improved stent location and to detect optimal release and deployment. We defined the SBS and IVUS criteria for accuracy of stent location and adequate stent deployment. IVUS findings showed that stent location was generally good. The location was accurate in 48 (82.8%) and inadequate stent deployment was observed in 10 of 58 (17.2%). Eight SBS images showed inadequate stent expansion. SBS predicted inadequate findings of IVUS with 100% specificity and 80% sensitivity, while a significant positive correlation was observed between SBS-MSA and MSA by IVUS with a regression coefficient of 0.95.Imaging techniques have a primary role during ostial PCI. SBS is a simple and quick method that offers several advantages, enabling improved stent location, adequate stent expansion, and optimal apposition of the struts to the wall. SBS imaging could be conventionally used during ostial PCI, especially in centers where IVUS is not used routinely. (Int Heart J 2015; 56: 37-42) Key words: Percutaneous coronary intervention, Apposition, Stent location, Stent expansion P ercutaneous coronary intervention (PCI) of coronary ostial lesions is technically difficult leading to higher rates of adverse cardiac events compared with PCI of non-ostial coronary lesions.1-4) The challenges of PCI of an ostial lesion may depend not only upon the lesion location (ie, aorto-ostial versus non-aorto-ostial), but also on the plaque burden and lesion morphology. Ostial lesions are less compliant compared with non-ostial lesions due to increased fibrosis, calcification, and muscular/elastic tissue, the latter of which is especially evident in aorto-ostial disease.5) Complete stent coverage of ostial lesions can be problematic, with inaccurate stent placement leading to higher rates of restenosis. 6) Compared with coronary angiography, intravascular ultrasound (IVUS) allows for a more detailed assessment of coronary anatomy, including plaque characteristics and morphology, vessel size, and precise localization of the true ostium.7) The only reliable way to exclude insufficient stent deployment with certainty is IVUS.8-10) However, in daily practice, this technique is not used routinely because it is expensive, time-consuming, and there is a learning curve (requiring trained operators and laboratory staff).11) Moreover, it is difficult to obtain an accurate location of the stent before the stent is released. Stent boost sub...