Assessment of Oral Health and Healthy Habits in Adult Patients with Congenital Hemophilia

Abstract

Objectives The objective of our study was to assess the current knowledge, the oral health status, and the pro-health needs of patients with hemophilia. Materials and Methods The study included 77 patients with known hemophilia. The study included the assessment of dental indicators related to caries incidence (decayed, missing, and filled teeth [DMFT] and decayed, missing, and filled permanent teeth or surfaces [DMFS]), caries treatment (treatment index), oral hygiene status (Approximal Plaque Index [API] and simplified oral hygiene index [OHI-S]), and periodontal status (bleeding on probing [BoP]). A questionnaire addressed symptoms of hemorrhagic diathesis and health-promoting habits. The influence of routine management (“on-demand” vs. prophylactic therapy), type of hemophilia (A, B), and severity of clotting factor deficiency (mild, moderate, or severe) on oral health was assessed. Statistical Analysis The tests used in the study were Shapiro–Wilk, Mann–Whitney, Kruskal–Wallis, and Dunn's tests. The level of significance was set at p < 0.05. Results Patients with hemophilia showed a higher prevalence of caries compared with patients without hemorrhagic diathesis (DMFT 14 and 9, and DMFS 30 and 15, respectively), and they also presented a higher bleeding index value during probing and worse effectiveness of hygienic interdental procedures. The type of therapy and secondary prophylaxis used and the type and severity of hemophilia did not affect the oral health status. Conclusions Patients with hemophilia have an increased risk of developing dental caries. Undertaking educational activities related to the prevention of oral diseases is necessary to improve oral health.

Oral health in individuals with bleeding disorders: A systematic review and meta‐analysis

“…Subsequently, the full texts of the 26 records were read and assessed. Finally, 22 articles were included in the final analysis 1–7,11–25 . Of the 22 articles assessed, nine quantitative assessments were included in the Meta analysis (Figure 1).…”

“…Finally, 22 articles were included in the final analysis. [1][2][3][4][5][6][7][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25] Of the 22 articles assessed, nine quantitative assessments were included in the Meta analysis (Figure 1).…”

A Panoramic X-ray as a Supportive Diagnostic Tool for the Screening of Osteoporosis in Patients with Hemophilia A and B

“…The study group comprises 50 men aged 19 to 65 (median 36.5) diagnosed with mild, moderate or severe congenital hemophilia A or B, treated at the Department of Hematology and Bone Marrow Transplantation (DHBM). Oral examination was performed in 77 patients, over 70% of patients under the care of the center [16]. Radiographs were assessed in 50 patients; patients for whom it was not possible to obtain a technically correct radiograph and patients who refused to undergo radiological diagnostics were excluded from the study.…”

Current Status and Challenges in Delivering Comprehensive Care for Patients with Hemophilia

“… 57 Conversely, tooth decay and periodontal disease, if severe and untreated, are not infrequent causes of irreversible bleeding. 58 Properly maintained gums are less susceptible to bleeding during activities such as brushing. Thus, individuals with hemophilia should become familiar with daily oral care practices.…”