1996
DOI: 10.1136/thx.51.2.202
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Assessment of oxygen supplementation during air travel.

Abstract: Background -The aim of this study was to simulate an in flight environment at sea level with a fractional inspired concentration ofoxygen (Fio2) of0-15 to determine how much supplemental oxygen was needed to restore a subject's oxygen saturation (Sao2) to 90% or to the level previously attained when breathing room air (Fio2 of 0-21). Methods -Three groups were selected with normal, obstructive, and restrictive lung function. Using a sealed body plethysmograph an environment with an Fio2 of0-15 was created and … Show more

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Cited by 62 publications
(55 citation statements)
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“…Because of the relative inaccessability of hypobaric chambers the development of a simple HIT which can be used in respiratory function laboratories for the preflight assessment of patients is potentially beneficial. To ensure the protocol would be applicable in routine laboratories, the use of a plethysmograph [3] and expensive cylinders of hypoxic gas mixtures was avoided. The simple and elegant method of VOHRA and KLOCKE [11] using a Venturi mask supplied with nitrogen was therefore adopted.…”
Section: Discussionmentioning
confidence: 99%
“…Because of the relative inaccessability of hypobaric chambers the development of a simple HIT which can be used in respiratory function laboratories for the preflight assessment of patients is potentially beneficial. To ensure the protocol would be applicable in routine laboratories, the use of a plethysmograph [3] and expensive cylinders of hypoxic gas mixtures was avoided. The simple and elegant method of VOHRA and KLOCKE [11] using a Venturi mask supplied with nitrogen was therefore adopted.…”
Section: Discussionmentioning
confidence: 99%
“…Pressurised aircraft do not maintain a sea level pressure during flight for practical reasons. During commercial flights most cabins are pressurised to an equivalent altitude of 5000-8000 ft, which equates to an inspired oxygen fraction of 0.17-0.15 at sea level [5]. Current US Federal Aviation Regulations specify that pressurised cabins must provide a cabin pressure altitude of not more than 8000 ft (2440 m) at the maximum operating altitude of the ............................................................................................................................................................................................................... (FAA, 1996), in order to maintain the partial pressure of oxygen [12].…”
Section: Discussionmentioning
confidence: 99%
“…Many flights are also of a longer duration than previously, up to 16 h non-stop [1,2]. The reduction in the fraction of inspired oxygen at altitude leads to a reduction in oxygen saturation (S p O 2 ) in both healthy passengers and in those with coexisting medical conditions during actual and simulated aeromedical flights [3][4][5][6][7].…”
mentioning
confidence: 99%
“…CRAMER et al [18] used a modified body plethysmograph as an exposure chamber, a method that has the advantage of eliminating the need for the patient to breathe through a mask, which some patients find uncomfortable or inhibiting. The FI,O 2 within the exposure chamber needs to be closely monitored to ensure that it remains within the desired range.…”
Section: Methods Of Predicting Hypoxiamentioning
confidence: 99%