Assessment of phenolic content and free radical-scavenging capacity of some Thai indigenous plants

Maisuthisakul, Pitchaon; Suttajit, Maitree; Pongsawatmanit, Rungnaphar

doi:10.1016/j.foodchem.2005.11.032

Cited by 477 publications

(327 citation statements)

References 23 publications

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“…DPPH (2,2 Diphenyl -1 -picryhydrazyl radical) radical scavenging was assessed according to the literature procedure (Gadow et al, 1997;Maisuthisakul et al, 2007). 100 μL of the diluted extract (prepared at four different concentrations to provide 10 to 90% inhibition) were added into 4 mL of freshly prepared DPPH solutions (6 x 10 -5 M in MeOH).…”

Section: Determination Of Antioxidant Capacity Using Dpphmentioning

confidence: 99%

Influence of shooting period and extraction conditions on bioactive compounds in Turkish green tea

Balci

Özdemir

2016

Food Sci. Technol

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Section: Determination Of Antioxidant Capacity Using Dpphmentioning

confidence: 99%

Influence of shooting period and extraction conditions on bioactive compounds in Turkish green tea

Balci

Özdemir

2016

Food Sci. Technol

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“…Besides, free radicals react with food lipids and cause lipid peroxidation that deteriorates food quality, affecting the colour, flavour, taste, texture and nutritional value of foods (Ferreira et al 2007, Biglari et al 2008. Antioxidants are used in lipid-containing foods to minimize rancidity, preventing off-flavour, delay the formation of oxidation products, maintain nutritional quality and prolong the shelf life of food products (Maisuthisakul et al 2007). …”

Section: Introductionmentioning

confidence: 99%

Optimization of extraction time and temperature on antioxidant activity of Schizophyllum commune aqueous extract using response surface methodology

Yim

Chye²,

Rao

et al. 2011

J Food Sci Technol

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Central composite design of response surface methodology (RSM) was employed to optimize the extraction time (X 1 : 99.5-290.5 min) and temperature (X 2 : 30.1-54.9°C) of Schizophyllum commune aqueous extract with high antioxidant activities and total phenolic content (TPC). Results indicated that the data were adequately fitted into four second-order polynomial models. The extraction time and temperature were found to have significant linear, quadratic and interaction effects on antioxidant activities and TPC. The optimal extraction time and temperature were: 290.5 min and 35.7°C (DPPH • scavenging ability); 180.7 min and 41.7°C (ABTS •+ inhibition ability); 185.2 min and 42.4°C (ferric reducing antioxidant power, FRAP); 290.5 min and 40.3°C (TPC). These optimum conditions yielded 85.10%; 94.31%; 0.74 mM Fe 2+ equivalent/100 g; 635.76 mg gallic acid equivalent/100 g, respectively. The yields of antioxidant activities and TPC obtained experimentally were close to its predicted values. The establishment of such model provides a good experimental basis employing RSM for optimizing the extraction time and temperature on antioxidants from S. commune aqueous extract.

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“…LSFJ contains polyphenolic compounds (6.8 mg/10 mL of juice, obtained by our group). The antioxidant activity of polyphenolic compounds from others plants have been reported earlier (Karou et al, 2005;Maisuthisakul et al, 2007).…”

Section: Discussionmentioning

confidence: 58%

Cardioprotective Effect of Lagenaria siceraria (Molina) Standley (Cucurbitaceae) Fruit Juice on Doxorubicin Induced Cardiotoxicity in Rats

Fard¹,

Naseh²,

Bodhankar³

et al. 2010

American J. of Pharmacology and Toxicology

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Problem statement:The cardio toxicity of Doxorubicin (Dox) has limited its use as an anticancer drug. The aim of present study was to investigate the cardio protective effect of Lagenaria Siceraria (Cucurbitaceous) Fruit Juice (LSFJ) against the cardio toxicity of Dox in rats. Approach: Male wistar rats (250-300 g) were randomly divided into four groups. Group I-was control, Group II-Dox (10 mg kg −1 ), groups III and IV-Dox + LSFJ (5 and 10 mL kg −1 for 18 days). Dox (10 mg kg −1 iv) was administered in group II, III and IV on day 16. After anesthetizing the animals on the 18th day, Electrocardiogram (ECG) was recorded and blood was investigated for Creatine Kinase-MB is enzyme (CK-MB), Lactate Dehydrogenase (LDH) and Aspartate Aminotransferase (AST) while determination of Superoxide Dismutase (SOD), Reduced Glutathione (GSH), Lipid Per Oxidation (LPO) and histopathology was carried out for heart. Results: Group 3 and 4 of animals showed decreased QT interval (p<0.05) and was non significant in ST interval and heart rate compared to Group 2. Significant decrease in serum CK-MB and AST of group 3 (p<0.05) and group 4(p<0.01) of animals was observed as compared to group II. In group 4 significant increase in the level of GSH (p<0.01) and decrease in MDA content (p<0.001) was observed as compared to group 2, whereas SOD was non-significant. Histopathological study of LSFJ10 mL kg −1 treated group showed protection against myocardial toxicity induced by doxorubicin. Conclusion: It is concluded that Lagenaria siceraria fruit juice possessed cardio protective effect at dose of 10 mL kg −1 against doxorubicin induced cardio toxicity in rats.

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Assessment of phenolic content and free radical-scavenging capacity of some Thai indigenous plants

Cited by 477 publications

References 23 publications

Influence of shooting period and extraction conditions on bioactive compounds in Turkish green tea

Influence of shooting period and extraction conditions on bioactive compounds in Turkish green tea

Optimization of extraction time and temperature on antioxidant activity of Schizophyllum commune aqueous extract using response surface methodology

Cardioprotective Effect of Lagenaria siceraria (Molina) Standley (Cucurbitaceae) Fruit Juice on Doxorubicin Induced Cardiotoxicity in Rats

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