Background: Sedentary lifestyle are public health concerns that threatening human health, and sedentary behavior(SB) intervention in the workplace has attracted wide attention in the field of public health.Methods: A quasi-experimental design with randomized treatment assignment will be used to test the effect of breaking up prolonged sitting during work hours on SB and cardiometabolic risk in professional office workers in China. There are two intervention protocols: A) Interrupting SB prompted by timer app every 60min of sitting during work hours; B) Participating in 30 min of moderate to vigorous physical activity at work. The intervention will be implemented in 2 worksite locations for 12 months. Study outcomes include SB and physical activity measured by accelerometry, and cardiometabolic risk factors and will be assessed at baseline and 12-month posttest.
Discussion and conclusion:The intervention protocols integrate a few health behavior promotion theories, will provide a reference for selecting appropriate intervention measures to conduct an effectiveness on SB interruption at work, decrease in SB duration, and influence on cardiovascular risk factors.