The study was done on the effect of water contamination on human health. The review revealed a complex network of factors contributing to water contamination, including home sewage, industrial discharges, pesticides, plastics, and systemic management deficiencies. The study highlighted the widespread effects on human health, including skin disorders, serious illnesses like cancer and diarrheal infections, particularly affecting children. It emphasized the need for synchronized efforts to alleviate pollution sources, focusing on sustainable farming methodologies and responsible waste management. The study also explored advanced wastewater treatment techniques, highlighting the urgent need for their widespread use worldwide. However, the study acknowledged limitations, such as geographical scope and contamination origins. Recommendations included a comprehensive strategy involving sustainable behaviors, strict laws, and advanced treatment technology. The study emphasized the need for governments, companies, and communities to work together to implement strong legislation, improve infrastructure, and increase knowledge about water quality. Addressing these challenges requires a holistic approach, focusing on mitigating constraints through ongoing research, innovation, and international collaboration.