Assessment of PM2.5 exposure risk towards SDG indicator 11.6.2 – A case study in Beijing

Dong, Junwu; Wang, Yanhui; Wang, Lili; Zhao, Wenji; Huang, Chenguang

doi:10.1016/j.scs.2022.103864

Cited by 19 publications

(10 citation statements)

References 38 publications

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“…Authors such as Ehrlich et al (2018) consider density to be an essential variable in the analysis of climate risks. Furthermore, given the same concentration of PM2.5, more populated areas face greater risks of exposure (Dong et al, 2022). Therefore, it would be a variable worth taking into account in other geographical contexts.…”

Section: Resultsmentioning

confidence: 99%

Regional analysis of the sustainable development of two Mediterranean countries: Spain and Italy

Puertas

Martí

2022

Sustainable Development

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The 17 Sustainable Development Goals (SDGs) require the implementation of 167 targets aimed at eradicating poverty, protecting the planet and improving the quality of life of humankind. The United Nations calls for uniform sustainable development at the global, local and individual levels. This research pursues a twofold objective: first, to obtain evidence on the extent to which the achievement of the (SDGs) may be uniform across territories; second, to identify the socioeconomic characteristics that contribute to sustainable development. The empirical analysis has been carried out using clustering, cross efficiency and contingency tables applied to statistical information from 101 municipalities in Spain and Italy. The results provide evidence of inequalities between territories, revealing that only in the dimensions People (SDGs 1, 2, 3, 4, and 5) and Prosperity (SDGs 7, 8, 9, 10, and 11) has the desired homogeneity been attained. Notable differences are found in the degree of compliance with the other SDGs. Furthermore, it is shown that the socioeconomic characteristics associated with the geographical location contribute substantially to the gap between municipalities. In order to ensure countries' sustainable development, there is a need for environmental policies adapted to the specific features of each region.

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Section: Resultsmentioning

confidence: 99%

Regional analysis of the sustainable development of two Mediterranean countries: Spain and Italy

Puertas

Martí

2022

Sustainable Development

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“…Just as differences in the size of PM particles affect lung health, the composition of PM particles produced by vehicle emissions, industrial processes, construction activities, and natural sources such as pollen and dust is also important. Particulate matter is used as a key indicator of ambient air quality and to measure its potential impact on human health and the environment [ 54 ]. Significant research efforts are underway to improve the composition and properties of particulate matter, providing the basis for accurate and reliable air quality measurements.…”

Section: Discussionmentioning

confidence: 99%

Particulate Matter Induces Oxidative Stress and Ferroptosis in Human Lung Epithelial Cells

Ahn,

Yim,

Yoo

2024

Toxics

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Numerous toxicological studies have highlighted the association between urban particulate matter (PM) and increased respiratory infections and lung diseases. The adverse impact on the lungs is directly linked to the complex composition of particulate matter, initiating reactive oxygen species’ (ROS’) production and consequent lipid peroxidation. Excessive ROS, particularly within mitochondria, can destroy subcellular organelles through various pathways. In this study, we confirmed the induction of ferroptosis, an iron-dependent cell death, upon exposure to an urban PM using RT-qPCR and signaling pathway analysis. We used KRISS CRM 109-02-004, the certified reference material for the analysis of particulate matter, produced by the Korea Research Institute of Standards and Science (KRISS). To validate that ferroptosis causes lung endothelial toxicity, we assessed intracellular mitochondrial potential, ROS overproduction, lipid peroxidation, and specific ferroptosis biomarkers. Following exposure to the urban PM, a significant increase in ROS generation and a decrease in mitochondrial potential were observed. Furthermore, it induced hallmarks of ferroptosis, including the accumulation of lipid peroxidation, the loss of antioxidant defenses, and cellular iron accumulation. In addition, the occurrence of oxidative stress as a key feature of ferroptosis was confirmed by increased expression levels of specific oxidative stress markers such as NQO1, CYP1B1, FTH1, SOD2, and NRF. Finally, a significant increase in key ferroptosis markers was observed, including xCT/SLC7A11, NQO1, TRIM16, HMOX-1, FTL, FTH1, CYP1B1, CHAC1, and GPX4. This provides evidence that elevated ROS levels induce oxidative stress, which ultimately triggers ferroptosis. In conclusion, our results show that the urban PM, KRISS CRM, induces cellular and mitochondrial ROS production, leading to oxidative stress and subsequent ferroptosis. These results suggest that it may induce ferroptosis through ROS generation and may offer potential strategies for the treatment of lung diseases.

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“…Therefore, the intersection and integration of multiple subjects may become the trend of research in the future. In addition, Liu, Shen, Dong, and other scholars have shown how to reasonably evaluate the temporal and spatial distribution pattern of PM 2.5 and quantitatively analyze the PM 2.5 exposure and the health risks are a key problem to be solved [44,62,63]. Meanwhile, Miranda, Santana, and other scholars pointed out that predicting air pollution levels such as PM 2.5 in different cities under different environmental conditions through modeling and data simulation can be an important research direction for future research [64,65].…”

Section: Discussionmentioning

confidence: 99%

“…Take China as an example, there has been a significant increase in cases of atherosclerosis, congenital malformations, and childhood respiratory diseases during this period [41,42]. This trend has garnered global attention, leading to the formulation of Sustainable Development Goals (SDGs) with a specific target (11.6.2) for controlling PM 2.5 , which were first proposed by governments worldwide during the Rio+20 UN Conference in June 2012 [43,44]. In response, countries began to enact a series of policies to promote greener, more sustainable development after 2012 [45,46].…”

Section: Descriptive Bibliometric Analysis Of Publicationsmentioning

confidence: 99%

A Review of Global PM2.5 Exposure Research Trends from 1992 to 2022

Jia

Chen

et al. 2023

Sustainability

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Exposure to air pollutants of fine particulate matter (PM2.5) is a major threat to human health. Research on PM2.5 exposure has been on the rise in recent years, but there has been a lack of systematic literature analysis in this field. To address this research gap, we conducted a bibliometric analysis of the existing publications on PM2.5 exposure over the past three decades and analyzed the current state and historical trends of research using the open-access tool, KNIME. Our results show that the number of publications on PM2.5 exposure has been increasing at an accelerating rate over the last 30 years. The authors of the publications are primarily from developed nations, such as countries in North America, Europe, East Asia, and Oceania. Published research is mainly from the fields of Environmental Sciences and Ecology, Environmental Sciences, and Public, Environmental and Occupational Health. The main research hotspots are exposure, air pollution, and PM2.5. Research is trending toward the intersection and integration of multiple subjects. Our results highlight the rapid growth of PM2.5-related research and provide insights into the structure, impact, and trends of this interdisciplinary field.

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Assessment of PM2.5 exposure risk towards SDG indicator 11.6.2 – A case study in Beijing

Cited by 19 publications

References 38 publications

Regional analysis of the sustainable development of two Mediterranean countries: Spain and Italy

Regional analysis of the sustainable development of two Mediterranean countries: Spain and Italy

Particulate Matter Induces Oxidative Stress and Ferroptosis in Human Lung Epithelial Cells

A Review of Global PM2.5 Exposure Research Trends from 1992 to 2022

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