Assessment of population exposure to air pollution by benzene

Tchepel, Oxana; Penedo, Ana; Gomes, Mónica

doi:10.1016/j.ijheh.2007.01.008

Cited by 10 publications

(4 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Benzene penetrates the body even at low concentrations [2] and was recognized as a priority pollutant by the US Environmental Protection Agency (EPA) [3]. Benzene concentrations vary depending on geographic location [4,5], duration or route of exposure, and individual susceptibility factors such as age, gender or lifestyle. Various sources of benzene exposure include drinking contaminated water or food, smoking cigarettes, breathing secondhand cigarette smoke, vehicle exhaust or petroleum fuels, vaping e-cigarettes, using paint or detergent products [6][7][8][9][10][11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Acarbose Protects From Central and Peripheral Metabolic Imbalance Induced by Benzene Exposure

Debarba

Mulka

Lima

et al. 2020

Preprint

View full text Add to dashboard Cite

Abbreviations:CNS, central nervous system; ARC, arcuate nucleus of the hypothalamus; DMH, dorsomedial hypothalamic nucleus; LHA, lateral hypothalamus; PVH, paraventricular hypothalamic nucleus; AbstractBenzene is a well-known human carcinogen that is one of the major components of air pollution. Sources of benzene in ambient air include cigarette smoke, e-cigarettes vaping and evaporation of benzene containing petrol processes. While carcinogenic effects of benzene exposure have been well studied, less is known about metabolic effects of benzene exposure.We show that chronic exposure to benzene at low levels induces severe metabolic imbalance in a sex-specific manner, which is associated with hypothalamic inflammation and endoplasmic reticulum (ER) stress. Benzene exposure rapidly activates hypothalamic ER stress and neuroinflammatory responses in male mice, while pharmacological inhibition of ER stress response by inhibiting IRE1α-XBP1 pathway significantly alleviates benzene-induced glial inflammatory responses. Additionally, feeding mice with Acarbose, a clinically available anti-diabetes drug, protected against benzene induced central and peripheral metabolic imbalance. Acarbose imitates the slowing of dietary carbohydrate digestion, suggesting that choosing a diet with a low glycemic index might be a potential strategy for reducing the negative metabolic effect of chronic exposure to benzene for smokers or for people living/working in urban environments with high concentrations of exposure to automobile exhausts.

show abstract

Section: Introductionmentioning

confidence: 99%

Acarbose Protects From Central and Peripheral Metabolic Imbalance Induced by Benzene Exposure

Debarba

Mulka

Lima

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…Until recently the risk posed by current air benzene concentrations to soil organisms has been difficult to model, due to uncertainties related to exposure and effect, susceptibility variations, and the limitations related to multiple or mixed exposures to many chemicals (Strebel et al, 2013;Tchepel et al, 2007). Overall, the present data suggest that A. officinalis is a good indicator of benzene exposure and seem to validate this species as a new experimental animal model.…”

Section: Resultsmentioning

confidence: 65%

Validation of Armadillo officinalis Dumèril, 1816 (Crustacea, Isopoda, Oniscidea) as a bioindicator: In vivo study of air benzene exposure

Agodi

Conti

Barchitta

et al. 2015

Ecotoxicology and Environmental Safety

View full text Add to dashboard Cite

“…Benzene can be emitted from traffic activity, industrial activities, gas stations, biomass burning, etc. Several studies highlighted the risk to human health when exposed to benzene (Li et al, 2014;Schiavon et al, 2015;Tchepel, Penedo, & Gomes, 2007). There are several studies on benzene pollution, the primary sources of benzene emission, and the suggestion to reduce benzene concentrations (Park et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Identify benzene pollution, sources of benzene emission and suggest mitigation measures for Ho Chi Minh City, Vietnam

Bang Ho,

Khue Vu,

Nguyen

et al. 2023

IOP Conf. Ser.: Earth Environ. Sci.

View full text Add to dashboard Cite

In Ho Chi Minh City (HCMC), benzene concentration was higher than the benzene standard of Vietnam technical regulation for ambient air. However, there is a lack of consideration for benzene sources and mitigation suggestions. This study aims (1) to analyze benzene concentration in HCMC and (2) to calculate benzene emission from primary sources to identify the contribution of benzene from the main sources. Besides, we gave measures to reduce benzene pollution. Our case study is in Ho Chi Minh City (HCMC), Vietnam. Firstly, we analyzed benzene concentration data from the Department of Environment and Resources. The data included 30 sampling locations in Ho Chi Minh City from familiar pollution sources: traffic (19 locations), industry (4 locations), resident areas (4 locations), and ambient regions (3 locations). Secondly, we used benzene emission results to identify the primary sources. Thirdly, we suggested mitigation measures to reduce the benzene concentration in HCMC. Compared to the National technical regulation of hazardous substances in the ambient air of Vietnam (QCVN 06:2009/BTNMT), the benzene concentration exceeded the Vietnamese standard. Significantly, the traffic had the highest contribution, up to 90% of total benzene emission, followed by industry and residential activity. Our findings gave a comprehensive picture of benzene pollution and the contribution of primary sources. We also suggested ten solutions to reduce benzene concentration in HCMC.The results can help the local government’s decision to focus to the significant sources and reduce the benzene pollution in HCMC.

show abstract

Assessment of population exposure to air pollution by benzene

Cited by 10 publications

References 6 publications

Acarbose Protects From Central and Peripheral Metabolic Imbalance Induced by Benzene Exposure

Acarbose Protects From Central and Peripheral Metabolic Imbalance Induced by Benzene Exposure

Validation of Armadillo officinalis Dumèril, 1816 (Crustacea, Isopoda, Oniscidea) as a bioindicator: In vivo study of air benzene exposure

Identify benzene pollution, sources of benzene emission and suggest mitigation measures for Ho Chi Minh City, Vietnam

Contact Info

Product

Resources

About