Assessment of Portal Venous and Hepatic Artery Haemodynamic Variation in Non-Alcoholic Fatty Liver Disease (NAFLD) Patients

Balasubramanian, Padhmini; Boopathy, Vinoth; Ezhumalai, G; Venkatesh, Basavaiya Prabhu

doi:10.7860/jcdr/2016/20697.8267

Cited by 15 publications

(27 citation statements)

References 17 publications

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“…Another significant finding of our study was that the liver span of fatty liver was positively correlated with the steatosis percentage. In line with this finding, the study conducted by Balasubramanian et al addressing adults has reported that the liver span of adult patients with NAFLD was significantly higher than that of healthy controls and was correlated with the severity of the fatty liver (28).…”

Section: Discussionsupporting

confidence: 56%

“…Balasubramanian et al reported that the velocity of the portal flow and the portal vein pulsatility index in patients with fatty liver were significantly lower than those of the controls and were inversely correlated with the severity of fatty liver (28). In addition, some studies have reported similar findings with respect to the velocity of the portal flow and the portal vein pulsatility index (29,30).…”

Section: Discussionmentioning

confidence: 92%

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Doppler perfusion index in adolescents with non-alcoholic fatty liver disease

et al. 2020

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Introduction: Non-alcoholic fatty liver disease (NAFLD) as a multi-factorial disorder is the most common cause of abnormal liver function tests in adolescents. Objectives: The present study aimed to assess Doppler perfusion index (DPI) in adolescents with NAFLD as compared with healthy subjects. Patients and Methods: Thirty-seven adolescents with NAFLD and 25 healthy individuals were enrolled in the study. Hemodynamic indices were measured using a color Doppler ultrasound machine. Severity of fatty liver disease and steatosis grade were assessed using FibroScan. The measured indices were peak systolic velocity (PSV), resistive index (RI), end-diastolic velocity (EDV), time-averaged mean velocity (TAMV), time-averaged peak velocity (TAPV), portal venous blood flow (PVBF) volume, hepatic arterial blood flow (HABF) volume, and DPI. Results: The mean of DPI in the case and control groups was 0.31±0.11 and 0.31±0.09, respectively (P=0.972). HABF volume was significantly lower in the case group as compared with the control group (103.8 versus 153.3 respectively, P=0.015). PSV, TAMV, mean velocity, and PVBF volume were significantly lower in the case group as compared with the control group (P<0.05). Patients with a higher steatosis grade indicated a significantly lower mean of PSV and TAMV portal than controls (P<0.05). Conclusion: DPI was similar in adolescents with NAFLD and healthy subjects and was not associated with severity of fatty liver disease and steatosis grade. In addition, the percentage of steatosis would be increased with increased liver span.

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Section: Discussionsupporting

confidence: 56%

Section: Discussionmentioning

confidence: 92%

Doppler perfusion index in adolescents with non-alcoholic fatty liver disease

et al. 2020

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“…17,18 A compensatory increase in hepatic artery blood flow, which results in relatively normal values of total liver blood flow in these patients, as shown in our results, has been reported in patients with NAFLD. 39 As ICGePDR and ICG-R15 account for the global liver blood flow, the specific role of hepatic artery and portal vein cannot be determined.…”

Section: Discussionmentioning

confidence: 99%

Dexmedetomidine metabolic clearance is not affected by fat mass in obese patients

Rolle

Paredes

Cortínez

et al. 2018

British Journal of Anaesthesia

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“…Abnormal waveforms of the hepatic veins (normal triphasic pattern disappears) [81] Velocity of the portal flow (flow peak maximum velocity and mean flow velocity) and the portal vein pulsatility index (VPI) are significantly lower in patients with fatty liver when compared to the controls; it also corelates with the severity of the fatty liver [82] US elastography Fibrosis assessment by means of hepatic stiffness measurement Steatosis evaluation by the instrumentality of the Controlled Attenuation Parameter (CAP) [14]…”

Section: Doppler Usmentioning

confidence: 99%

Performance of Ultrasound Techniques and the Potential of Artificial Intelligence in the Evaluation of Hepatocellular Carcinoma and Non-Alcoholic Fatty Liver Disease

Lupșor-Platon

Şerban

Silion

et al. 2021

Cancers

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Global statistics show an increasing percentage of patients that develop non-alcoholic fatty liver disease (NAFLD) and NAFLD-related hepatocellular carcinoma (HCC), even in the absence of cirrhosis. In the present review, we analyzed the diagnostic performance of ultrasonography (US) in the non-invasive evaluation of NAFLD and NAFLD-related HCC, as well as possibilities of optimizing US diagnosis with the help of artificial intelligence (AI) assistance. To date, US is the first-line examination recommended in the screening of patients with clinical suspicion of NAFLD, as it is readily available and leads to a better disease-specific surveillance. However, the conventional US presents limitations that significantly hamper its applicability in quantifying NAFLD and accurately characterizing a given focal liver lesion (FLL). Ultrasound contrast agents (UCAs) are an essential add-on to the conventional B-mode US and to the Doppler US that further empower this method, allowing the evaluation of the enhancement properties and the vascular architecture of FLLs, in comparison to the background parenchyma. The current paper also explores the new universe of AI and the various implications of deep learning algorithms in the evaluation of NAFLD and NAFLD-related HCC through US methods, concluding that it could potentially be a game changer for patient care.

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Assessment of Portal Venous and Hepatic Artery Haemodynamic Variation in Non-Alcoholic Fatty Liver Disease (NAFLD) Patients

Cited by 15 publications

References 17 publications

Doppler perfusion index in adolescents with non-alcoholic fatty liver disease

Doppler perfusion index in adolescents with non-alcoholic fatty liver disease

Dexmedetomidine metabolic clearance is not affected by fat mass in obese patients

Performance of Ultrasound Techniques and the Potential of Artificial Intelligence in the Evaluation of Hepatocellular Carcinoma and Non-Alcoholic Fatty Liver Disease

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