Assessment of Potential Duo Out of Syzigium aromaticum L., Zingiber officinale and Ocimum basilicum L. Leaves Extract for Extermination of Clinical Pathogens

Abstract

In last three decades numbers of new antibiotics have produced, but clinical efficacy of these existing antibiotics is being threatened by the emergence of multi drug resistant pathogens. This has forced scientist to search for new antimicrobial substances from various sources like the medicinal plants. Scope of this study is to evaluate the potential duo of Syzigium aromaticum L., Zingiber Officinale and Ocimum basilicum L against clinical pathogens; E. coli, S. aureus, B. cereus and P. vulgaris. Well diffusion method was adopted to study antimicrobial properties. The maximum zone of inhibition is produced by Syzigium aromaticum than other extracts S. aureus (17 mm) followed by B. cereus and P. vulgaris. Duo of Syzigium aromaticum and Zingiber officinale shown to have maximum antimicrobial property against E. coli, S. aureus, B. cereus and P. vulgaris which is expressed to be a best duo of extract and it is more potent (25 mm) for B. cereus. Duo of Zingiber Officinale and Ocimum basilicum and Ocimum basilicum and Syzigium aromaticum was least effective but in conclusion combined action of these extract is more enhanced than the individual extract. Our study indicates that phytoconstituents in combination can act better than individual. Therefore, they can be used for preserving various foodstuffs against microbial spoilage and it can be incorporated into medications for topical antifungal or antibacterial therapy.