Assessment of Predictors of Long-Term Effect of Complex Periodontal Treatment in Patients With Rheumatoid Arthritis

Глазунов, О А; Крячкова, Л.В.; Фесенко, Дмитро Володимирович

doi:10.35220/2078-8916-2019-34-4-12-16

Cited by 2 publications

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“…Для оцінки ступеня запального процесу в пародонті до і після лікування використовували папілярномаргінально-альвеолярний індекс (РМА) [8]. Втрату зубоясенного епітеліального прикріплення (ВЕП) визначали за допомогою градуйованого пародонтального зонда і виражали в мм, обраховуючи середнє значення за вимірами в 4 точках навколо кожного зуба [9]. Індекс кровоточивості ясен РВІ (за Mühlemann H. R.) визначали після зондування і виражали в балах -від 0 до 3 [10].…”

Section: матеріали і методи дослідженняunclassified

Index Assessment of Periodontal Tissue and Oral Hygiene of Patients at the Preoperative Stage of Treatment of Generalized Periodontitis Ii-Iii Degree

Futrak

2024

Ukr. Dent. Alm.

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A significant concern in modern dentistry is the increasing prevalence of periodontitis among the Ukrainian population. At present, there is a high frequency of diagnosis for initial-І degree and II-degree periodontitis in our country. However, a comprehensive comparative chronological analysis of index evaluation of periodontal tissues before the beginning of surgical treatment of generalized periodontitis of II and III degree of severity and after its completion has not yet been carried out, which determined the relevance of this study. Therefore, this study aims to address this gap in the literature. The aim of the study was to evaluate the state of periodontal tissues of patients at the preoperative stage of generalized periodontitis ІІ-ІІІІ degree treatment using periodontal and hygienic indices. Materials and Methods. Analysis of periodontal indices (PMA, PBI, Rtg-index, HEC, and tooth mobility score) was performed in 39 patients with GP II degree and 21 patients with GP III degree. Assessment of oral cavity hygiene by the OHI-S index was performed in patients with GP II-III degree and compared with data from 30 practically healthy people without dental diseases. The classification of M.F. Danilevsky (1994) with the additions of I.S. Mashchenko (2002) was used to evaluate the condition of periodontal tissues. Statistical processing of the research results was carried out using the software packages for statistical analysis of data from biomedical research “Microsoft Excel” and “Statistica”. Results and Discussion. As a result of the study, it was found that the values of periodontal indices: PMA ranged from 49.90±2.28% in patients with GP II degree to 64.25±3.22% in patients with GP III degree, p<0.01; PBI in patients with GP III degree was 1.2 times lower than in patients with GP II degree (2.39±0.05 points vs. 2.86±0.07 points, p<0.01; tooth mobility in patients with GP II degree was 2.00±0.10 points and was 1.5 times lower than in patients with GP III degree (2. 98±0.13 points), p<0.01; the value of HEC in patients with GP III degree was 1.5 times higher than in patients with GP II degree (3.57±0.10 mm vs. 2.45±0.08 mm, p<0.01); the values of Rtg-index in patients with GP ranged from 2.45±0.08 points in patients with GP II degree to 1.49±0.06 points in patients with GP III degree. According to the OHI-S index, in the control group and in patients with GP II degree, the values of the analyzed parameter were 1.82±0.13 points and 2.26±0.14 points, p<0. 05, while in patients with GP III degree the value of OHI-S index (2.92±0.16 points) corresponded to poor hygiene of oral cavity and exceeded the value in the control group by 1.6 times, p<0.01, and in patients with GP II degree by 1.3 times, p1<0.01. Conclusions. Thus, the need for comprehensive treatment of GP II-III degree was emphasized by high index scores of periodontal indices, which in patients with GP III degree were significantly higher compared with similar data in patients with GP II degree, p<0.01. The assessment of the hygienic state of the oral cavity in patients of both the comparison group and patients with advanced forms of GP degree the need to strengthen and improve individual, professional and motivational measures in this cohort of subjects.

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Section: матеріали і методи дослідженняunclassified

Index Assessment of Periodontal Tissue and Oral Hygiene of Patients at the Preoperative Stage of Treatment of Generalized Periodontitis Ii-Iii Degree

Futrak

2024

Ukr. Dent. Alm.

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Differential Drug Correction Cytokine and Prostaglandin Content in Blood and Gingival Fluid in Generalized Periodontitis Against the Background of Different Responsiveness of the Organization

Yarov,

Tkachenko,

Skripnikov

et al. 2023

Wiad Lek

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The aim is to study the dynamics of prostaglandins and cytokines in the blood and gingival fluid against the background of differential drug correction in patients with generalized periodontitis with different body reactivity. Materials and methods: 216 people aged 45 between 55 years with a diagnosis of generalized periodontitis of II, III degree of severity, chronic course were examined. Depending on the state of reactivity of the organism, the patients were divided into three groups: the first one consisted of people with normoreaction; the second group included patients with hyperreaction; the third group was made up of people with hyporeaction. The patients underwent patch surgery after the initial therapy. Initially, on the 1st, 2nd, 4th, 6th and 9th day after the operation, the content of prostaglandins (PG) E, E2, F2alpha and cytokines (IL-1β, IL-6, TNF, IL-4) in the blood and gingival fluid was performed. Patients with impaired body reactivity were treated with the proposed differential drug correction of cytokines and prostaglandins. Statistical processing of the obtained digital data was performed using the computer program Statistica 8.0. Results: The proposed differential drug correction in patients with generalized periodontitis against the background of hyper- and hyporeactivity of the body brings the content of IL-1β, IL-6, TNF, IL-4 to that of normal body reactivity, which ultimately restores the disturbed balance of pro- and anti-inflammatory cytokines in the blood and gingival fluid. On the 9th day, the content of all proinflammatory cytokines in the main groups was normalized and was commensurate with that of the body’s normal response (p>0.05). Differential drug correction led to normalization of the prostaglandin balance index on day 9 after flap surgery (p>0.05), indicating the establishment of a normal balance of eicosanoids in the blood and approximating the values of pro- and anti-inflammatory fractions of prostaglandins to those of normal body reactivity. Conclusion: Correction of altered parameters in patients with generalized periodontitis accompanied by impaired (hyper- and hypo-) reactivity of the body with bringing them to values that are typical for normoreactivity is considered to be a condition for optimizing mucosal wound healing after surgery and further stabilization of periodontal tissues.

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Assessment of Predictors of Long-Term Effect of Complex Periodontal Treatment in Patients With Rheumatoid Arthritis

Cited by 2 publications

References 4 publications

Index Assessment of Periodontal Tissue and Oral Hygiene of Patients at the Preoperative Stage of Treatment of Generalized Periodontitis Ii-Iii Degree

Index Assessment of Periodontal Tissue and Oral Hygiene of Patients at the Preoperative Stage of Treatment of Generalized Periodontitis Ii-Iii Degree

Differential Drug Correction Cytokine and Prostaglandin Content in Blood and Gingival Fluid in Generalized Periodontitis Against the Background of Different Responsiveness of the Organization

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