Assessment of predictors of the development of heavy forms of SARS-CoV-2 during pregnancy

Abstract

Aim: To evaluate the clinical significance of factors predisposing to the severe form of SARS-CoV-2 virus infection during pregnancy.Material and methods of study. 240 pregnant women with signs of acute respiratory disease were examined. All pregnant women were subjected to general clinical, obstetrical, and clinical-laboratory methods of examination (general analysis of blood, urine, biochemical blood tests, coagulogram, and PCR diagnostic test to verify SARS-CoV-2). To confirm the diagnosis of “community-acquired pneumonia” chest X-ray in two projections or computed tomography was performed.Results. Severe forms of coronavirus infection were most frequently diagnosed in the 20–29-year (34.3%) and 30–39-year (51.4%) age groups, in pregnant women who lived in an urban setting (82.9%), in pregnant women with a low level of education (85.7%), in pregnant women with a high index of extragenital pathology (100%), and women in the third trimester of pregnancy (67.7%).Conclusion. Risk factors for the severe form of SARS-CoV-2 include pregnant women in the age ranges 20-39 years; pregnant women who live in the urban setting; pregnant women with a low level of education; pregnant women with extragenital pathology; third-trimester pregnant women.