Assessment of predisposing factors in myofascial pain syndrome and the analgesic effect of trigger point injections - A primary therapeutic interventional clinical trial

Parthasarathy, Srinivasan; Sundar, Siyam; Mishra, Gayatri

doi:10.4103/ija.ija_6_19

Cited by 9 publications

(3 citation statements)

References 11 publications

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“…In addition to causing local pain in head, trunk, limbs, and other local muscles, CMPS also leads to muscle rigidity, limited joint movement, myasthenia and balance disorder 38. The morbidity of CMPS varies among different departments, such as 21% in department of orthopedics, 30% in department of internal medicine and 85–93% in the department of pain management 39. Currently, CMPS models have been well established in a variety of animals for medical research.…”

Section: Discussionmentioning

confidence: 99%

<p>Effects Of Heat-Conduction Dry Needling Therapy On TRPV1 Channel In Rats</p>

Wang¹,

Wang²,

Gao³

et al. 2019

JPR

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PurposeThis study was aimed to investigate the effects of heat-conduction dry needling therapy on chronic myofascial pain syndrome (CMPS) in rats and explore the analgesic mechanisms by measuring the mRNA expression of transient receptor potential cation channel subfamily V member 1 (TRPV1) in musculus gastrocnemius.MethodsSeventy-two rats were randomly divided into five groups. Group A was the control group containing eight normal rats. Group B was the model group where 16 rats developed CMPS in musculus gastrocnemius but received no treatments. Groups C, D, and E containing 16 CMPS rats in each group were the trial groups receiving heat-conduction dry needling therapy. In detail, rats in Group C received dry needling treatment at the heating temperature of 44°C. Rats in Group D received intramuscular injection of capsazepine before receiving dry needling treatment with the heating temperature at 44°C. Rats in Group E received dry needling treatment with the heating temperature at 40°C. The mRNA expression of TRPV1, protein kinase C (PKC), and interleukin (IL)-6 in the needle insertion points of musculus gastrocnemius was measured at 24 hrs and 7 days after dry needling therapy.ResultsCompared with untreated CMPS rats, the mRNA expression of TRPV1, PKC, and interleukin-6 (IL-6) was increased in rats receiving dry needling therapy with the heating temperature at 44°C for 24 hrs. However, the mRNA expression of TRPV1, PKC, and IL-6 in CMPS rats receiving injection of TRPV1 antagonist capsazepine into musculus gastrocnemius followed by temperature-needling at 44°C was analogous to that in untreated CMPS rats.ConclusionDry needling therapy with needles heated to 44°C could impact the activity of TRPV1/PKC/IL-6 pathway.

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Section: Discussionmentioning

confidence: 99%

<p>Effects Of Heat-Conduction Dry Needling Therapy On TRPV1 Channel In Rats</p>

Wang¹,

Wang²,

Gao³

et al. 2019

JPR

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“…Critical to this approach is the meticulous assessment of trigger point pain, which necessitates accurate localization of pain points, characterization of their nature, and evaluation of their impact on the patient’s quality of life ( 41 ). This assessment process encompasses an extensive collection of medical history, thorough physical examinations, detailed functional assessments, and comprehensive neurological evaluations.…”

Section: Discussionmentioning

confidence: 99%

Advancing musculoskeletal diagnosis and therapy: a comprehensive review of trigger point theory and muscle pain patterns

Zhai,

Jiang,

Chen

et al. 2024

Front. Med.

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Musculoskeletal disorders, especially chronic muscle pain, have a significant impact on public health, affecting millions worldwide. This review examines recent advancements in the diagnosis and management of myofascial pain, with a focus on the refined application of trigger point theory. This theory now incorporates an intricate model that blends biomechanical and neurophysiological mechanisms, essential for understanding the initiation and persistence of pain, and necessitating targeted therapeutic interventions. Utilizing a methodical approach, this paper categorizes muscle pain into three types: Muscle Belly Pain, Origin-Insertion Pain, and Referred Pain, as delineated in the most recent edition of “Myofascial Pain and Dysfunction—The Trigger Point Manual.” Such classification enhances diagnostic precision and therapeutic effectiveness by establishing a specific treatment protocol for each type of pain. The paper discusses the implications of various treatments, such as dry needling and manual therapy, which are informed by empirically derived trigger point charts. These charts are instrumental in pinpointing the exact locations of pain sources and customizing treatment plans. Moreover, this review critically assesses the evolving nature of trigger point charts and champions a holistic approach to pain management. It underscores the necessity of integrating biomechanics, kinesiology, and compensatory mechanisms to provide a comprehensive understanding that allows practitioners to address not only symptomatic pain but also the root causes of musculoskeletal disorders, thereby enhancing long-term patient care outcomes in clinical environments.

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“…Many studies have shown the success of TrPs injections in MPS. [3,8,9,[21][22][23][24] Some of the studies designed on the comparison of the injections such as lidocaine, botulinum toxin, and dry needling TrPs. [8,23] Kamanlı et al [23] found that all injections were effective but the most effective on pain was the lidocaine group.…”

Section: Discussionmentioning

confidence: 99%

Comparison Of Kinesiotaping, Trigger Point Injection, And Neural Therapy In The Treatment Of Acute Myofascial Pain Syndrome: A Randomized Controlled Study

Evcik¹

2023

Agri

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Objectives: Myofascial pain syndrome (MPS) is a regional painful soft-tissue disorder, characterized by trigger points (TrPs) and taut bands in the muscles. In this study, we aimed to compare the effectiveness of kinesio taping (KT), TrPs injection, and neural therapy (NT) on pain and disability in acute MPS. Methods: 104 patients with MPS in the cervical region were allocated into three groups. Group 1 (n=35) were treated with KT, Group 2 (n=35) received local anesthetic (LA) (lidocaine of 0.5%) TrPs injection, and Group 3 (n=34) received NT with the same LA solution. Patients were assessed by means of pain, pressure pain threshold (PPT), and disability. Pain severity was measured by Visual Analog Scale. The neck pain disability scale was used for assessing disability. PPT was measured by using an algometer. Measurements were taken before and after treatment of 3 rd and 7 th days. Results: There were improvements on pain and disability in all groups at the end of treatments at 3 rd day and during follow-up period (p<0.001) and no differences were found between the groups. There was significant difference in PPT values in TrPs injection and NT groups in comparisons between all time periods, however, the change, depending on time in the KT group, was not statistically significant. Conclusion:The results of this study show that all these three treatment methods found to be effective on pain relief and disability in acute MPS. In terms of PPT, injection treatments seem to be superior than KT.

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Assessment of predisposing factors in myofascial pain syndrome and the analgesic effect of trigger point injections - A primary therapeutic interventional clinical trial

Cited by 9 publications

References 11 publications

<p>Effects Of Heat-Conduction Dry Needling Therapy On TRPV1 Channel In Rats</p>

<p>Effects Of Heat-Conduction Dry Needling Therapy On TRPV1 Channel In Rats</p>

Advancing musculoskeletal diagnosis and therapy: a comprehensive review of trigger point theory and muscle pain patterns

Comparison Of Kinesiotaping, Trigger Point Injection, And Neural Therapy In The Treatment Of Acute Myofascial Pain Syndrome: A Randomized Controlled Study

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