Assessment of protein-calorie malnutrition.

Haider, Masood; Haider, Seemab

doi:10.1093/clinchem/30.8.1286

Cited by 86 publications

(29 citation statements)

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“…Gómez-Ambrosi et al observed a decrease in RBP-4 levels only after gastric bypass surgery with concomitant pronounced reductions in total-fat mass, postulating that RBP-4 might be considered as a dynamic marker of negative energy balance (41). Decreasing RBP-4 levels being associated with malnutrition has also been shown in previous investigations (42). However, in our study, data from intermediate routine follow-ups showed that all but four patients were weight stable (<5% variation) within 3 months before follow-up.…”

Section: Table 3 Cross-correlation Matrix For Changes In Parameters Omentioning

confidence: 54%

“…However, in our study, data from intermediate routine follow-ups showed that all but four patients were weight stable (<5% variation) within 3 months before follow-up. In addition, measurements of transferrin, which can also serve as a marker for malnutrition (42), were performed. Despite a significant decrease, baseline and follow-up values of all subjects were within the normal range and analysis revealed no association between RBP-4 and transferrin levels with regard to baseline, follow-up, or longitudinal measurements.…”

Section: Table 3 Cross-correlation Matrix For Changes In Parameters Omentioning

confidence: 99%

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Retinol‐binding Protein 4, Visceral Fat, and the Metabolic Syndrome: Effects of Weight Loss

Tschoner¹,

Sturm²,

Engl³

et al. 2008

Obesity

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1Retinol-binding protein 4 (RBP-4) has been reported to be associated with visceral-fat accumulation and parameters of the metabolic syndrome (MetS). In this study, we investigated the relationship between RBP-4, visceral fat, and the MetS during pronounced weight loss after bariatric surgery. Thirty-six subjects were examined before and 2 years after surgery. Abdominal-fat distribution was determined by ultrasound, metabolic parameters, and serum RBP-4 levels by standard methods. After surgery BMI decreased by 9.07 kg/m 2 , visceral-fat diameter (VFD) decreased by 60.6%, and RBP-4 serum levels by 16.6%. Change of RBP-4 levels was associated with reductions of waist (r = 0.364, P = 0.037), waist-to-hip ratio (WHR) (r = 0.415, P = 0.016), and VFD (r = 0.425, P = 0.010). MetS, as defined by International Diabetes Federation (IDF), was present in 19 patients at baseline and in nine patients at follow-up. Change in RBP-4 levels was the best predictor for the diagnosis of MetS at follow-up. In the subgroup without MetS at baseline, the decrease in RBP-4 levels (-28.1% vs. -6.3%, P = 0.020) and reduction in VFD (-66.9% vs. -55.0%, P = 0.038) were significantly greater compared to the subgroup with MetS. We demonstrate a marked decrease of RBP-4 levels after bariatric surgery, which correlates with reduction in visceral-fat mass. Furthermore, the extent of changes in RBP-4 levels differs according to the severity of the MetS.

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Section: Table 3 Cross-correlation Matrix For Changes In Parameters Omentioning

confidence: 54%

Section: Table 3 Cross-correlation Matrix For Changes In Parameters Omentioning

confidence: 99%

Retinol‐binding Protein 4, Visceral Fat, and the Metabolic Syndrome: Effects of Weight Loss

Tschoner¹,

Sturm²,

Engl³

et al. 2008

Obesity

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“…The different groups of nutritional status are those defined by Waterlow [ 161. The following levels of plasma proteins were considered abnormal as proposed in the literature [17]: Alb < 3.5 g/dl, RBP < 3 mg/dl, Tr < 200 mg/dl.…”

Section: Patientsmentioning

confidence: 99%

Nutritional status of children with leukemia

Kuvibidila

Ducos

et al. 1994

Med. Pediatr. Oncol.

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Children with cancer represent a high-risk group for protein-energy malnutrition due to side effects associated with treatment. Assessment of nutritional status at the time of diagnosis and during treatment is, therefore, essential for planning nutritional intervention. We studied the nutritional status of 25 children with leukemia [9 newly diagnosed/relapsed (D/R) leukemic patients and 16 children with leukemia in remission (REM)]. Plasma proteins (prealbumin, PA; albumin, Alb; transferrin, Tr; retinol-binding protein, RBP) and acute phase-reactant proteins (alpha 1-acid glycoprotein, AGP; C-reactive protein, CRP; ceruloplasmin, CER) were measured by radial immunodiffusion. Results show that there were no significant deficits in anthropometric measurements among leukemic children. In contrast, the mean levels of all plasma proteins, especially PA (P < 0.005), were significantly lower in the D/R group than in the REM group. All D/R children, compared to 59% of those in remission, had PA levels < 20 mg/dl. Only the D/R group had abnormal levels of RBP, Tr, and Alb. Children who were treated with prednisone had significantly higher mean levels of PA, RBP, and AGP than those who were not receiving prednisone. The mean levels of acute phase-reactant proteins in these leukemic children were comparable to those of healthy children. We conclude that mild/moderate malnutrition is common in leukemic patients at D/R and that PA seems to be the most sensitive indicator of visceral protein status.

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“…To detect depletion of protein supplied as well as metabolic alterations related to the malnutrition of tissues, invasive techniques such as measurement of biochemical indicators are required. The most widely used chemical indicators are visceral circulating proteins secreted by the liver (Haider and Haider 1984). These proteins, especially those with a quick turnover and a medium half-life, such as C reactive protein or prealbumin (Ingenbleek et al 1972), are useful for detecting subclinical and early stages of malnutrition.…”

Section: Biochemical Methodsmentioning

confidence: 99%

Measuring Nutrition Status, Physical Activity, and Fitness, with Special Emphasis on Populations at Nutritional Risk

Matsudo

2009

Nutrition Reviews

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Assessment of protein-calorie malnutrition.

Cited by 86 publications

References 0 publications

Retinol‐binding Protein 4, Visceral Fat, and the Metabolic Syndrome: Effects of Weight Loss

Retinol‐binding Protein 4, Visceral Fat, and the Metabolic Syndrome: Effects of Weight Loss

Nutritional status of children with leukemia

Measuring Nutrition Status, Physical Activity, and Fitness, with Special Emphasis on Populations at Nutritional Risk

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