“…The potential value of PLR evaluations in normal and disease conditions have been investigated in many studies in areas such as the autonomic nervous system, cognitive function, drug metabolism, pain response, psychology, fatigue, and sleep disorders. 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 There is a growing interest in diagnosis in these areas, and our custom-made pupillometer may be useful as an easily-applicable, non-invasive diagnostic tool.…”