Assessment of Quality-of-Life Outcomes

Testa, Marcia A.; Simonson, Donald C.

doi:10.1056/nejm199603283341306

Cited by 2,112 publications

(1,387 citation statements)

References 36 publications

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“…The Verbal Analogue-Scale is a simple instrument to assess current global quality of life [11]. The patient is asked to score their current global quality of life as a number between 0 (completely dissatisfied) and 100 (completely satisfied).…”

Section: Quality Of Life Measuresmentioning

confidence: 99%

“…Quality of life issues have become steadily more important and there has been an almost exponential increase in the use of quality of life evaluation as a technique of clinical research and in defining disease activity and response to treatment [11]. So far, data about the effect of CPAP on quality of life in patients with OSAS are limited [12±19], and there are only few prospective data on longterm effects.…”

mentioning

confidence: 99%

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Long-term treatment with continuous positive airway pressure improves quality of life in obstructive sleep apnoea syndrome

Sanner¹,

Klewer²,

Trumm³

et al. 2000

Eur Respir J

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Continuous positive airway pressure (CPAP) is an established treatment of obstructive sleep apnoea syndrome (OSAS). While it is known that CPAP reverses the pathological breathing pattern and improves daytime sleepiness, there are no sufficient data on the long‐term influence of CPAP on quality of life in patients with OSAS. Thirty‐nine patients with polysomnographically verified OSAS (apnoea/hypopnoea index (AHI): (mean±sd) 46.8±21.8 events·h‐1) were prospectively studied. All patients answered three quality of life measures (Complaint List, Nottingham Health Profile Part 1 (NHP), and Verbal Analogue‐Scale “quality of life”) prior to the initiation of CPAP therapy. After a mean of 9 months they were re‐evaluated by polysomnography, and completed the questionnaires once again. As expected, CPAP was effective in treating the sleep‐related breathing disorder. AHI decreased significantly from (mean±sd) 46.8±21.8 events·h‐1 to 3.3±6.3 events·h‐1, and minimum oxygen saturation increased from 77.1±9.3% to 89.9±3.4%, while body mass index did not change significantly (31.3±5.4 versus 30.8±4.8 kg·m‐2). During long‐term treatment with CPAP the Complaint List revealed a significant improvement of the extent of subjective impairment due to physical and general complaints (26.4±9.9 versus 20.4±11.1), and NHP a significant improvement of emotional reactions (19.8±21.7 versus 11.1±14.0) and energy (50.8±36.6 versus 32.1±36.7), but not of pain, physical mobility, sleep, social isolation, and quality of life as assessed by the Verbal Analogue‐Scale. It is concluded that long‐term continuous positive airway pressure therapy is effective in improving not only pathological breathing patterns but also parameters that estimate quality of life in patients with obstructive sleep apnoea syndrome.

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Section: Quality Of Life Measuresmentioning

confidence: 99%

mentioning

confidence: 99%

Long-term treatment with continuous positive airway pressure improves quality of life in obstructive sleep apnoea syndrome

Sanner¹,

Klewer²,

Trumm³

et al. 2000

Eur Respir J

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“…However, generic HRQL instruments allow comparison of the burden of disease between patient populations with different diseases [12]. Recently, as part of the EuroPrevall project, the first self-administered HRQL questionnaires specific for food allergy have been developed and validated: the Food Allergy Quality of Life Questionnaire-Child Form, -Teenager Form and -Adult Form (FAQLQ-CF, -TF, -AF).…”

Section: Introductionmentioning

confidence: 99%

Test–retest reliability of the Food Allergy Quality of Life Questionnaires (FAQLQ) for children, adolescents and adults

et al. 2009

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Objective The self-administered Food Allergy Quality of Life Questionnaire-Child Form (FAQLQ-CF), -Teenager Form (FAQLQ-TF) and -Adult Form (FAQLQ-AF) were recently developed within EuroPrevall, a multi-centred study of food allergy in Europe. The primary aim of this study was to evaluate the test-retest reliability of the FA-QLQ-CF, -TF and -AF. Methods One hundred and one Dutch patients (31 children, 34 adolescents and 36 adults) completed the FAQLQ twice with a 10-14 day interval. The intraclass correlation coefficient (ICC), Lin's concordance correlation coefficient (CCC) and Bland-Altman plots were used to assess testretest reliability. Results Test-retest reliability was excellent with ICCs and CCCs above 0.907, 0.975 and 0.951 for the FAQLQ-CF, -TF and -AF, respectively. Bland-Altman plots showed that the mean differences of the test and re-test were all close to zero for the FAQLQs. Conclusions The FAQLQs are reliable over a short time interval. The FAQLQs are not only excellent tools for group comparison studies, but also for monitoring individual patients.

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“…However, these indicators have lost part of their predictive value in wealthy societies where disease tends to be chronic, the mortality rate is extremely low and life expectancy has reached new heights. This scenario calls for concepts and measures of health that are more dynamic, and a strictly biomedical model is being replaced by one including patients' assessments of their own health, or Self Rated Health (SRH)[1,2]. …”

Section: Introductionmentioning

confidence: 99%

Opposite poles: A comparison between two Spanish regions in health-related quality of life, with implications for health policy

2010

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BackgroundAlthough health is one of the main determinants of the welfare of societies, few studies have evaluated health related quality of life in representative samples of the population of a region or a country. Our aim is to describe the health-related quality of life of the inhabitants of two quite different Spanish regions (Canary Islands and Catalonia) and to compare the prevalence of health problems between age-sex groups.MethodsWe use data obtained from the 2006 Health Survey of Catalonia and the 2004 Canary Islands Health Survey. With an ordinal composite variable measuring HRQOL we identify the association of characteristics of individuals with self-reported quality of life and test for differences between the regions.ResultsThe prevalence of problems in the five EQ-5 D dimensions increases with age and is generally higher for women than for men. The dimension with the highest prevalence of problems is "anxiety/depression", and there is noteworthy the extent of discomfort and pain among Canary Island women. Education, especially among the elderly, has an important effect on health-related quality of life.ConclusionsThere are substantial structural and compositional differences between the two regions. Regional context is a significant factor, independent of the compositional differences, and the effects of context are manifest above all in women. The findings show the importance of disease prevention and the need for improving the educational level of the population in order to reduce health inequalities.

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Assessment of Quality-of-Life Outcomes

Cited by 2,112 publications

References 36 publications

Long-term treatment with continuous positive airway pressure improves quality of life in obstructive sleep apnoea syndrome

Long-term treatment with continuous positive airway pressure improves quality of life in obstructive sleep apnoea syndrome

Test–retest reliability of the Food Allergy Quality of Life Questionnaires (FAQLQ) for children, adolescents and adults

Opposite poles: A comparison between two Spanish regions in health-related quality of life, with implications for health policy

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